The potential of natural herbal plants in the treatment and prevention of non-small cell lung cancer: An encounter between ferroptosis and mitophagy

Journal of Ethnopharmacology, Год журнала: 2025, Номер unknown, С. 119555 - 119555

Опубликована: Фев. 1, 2025

Язык: Английский

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Targeting ferroptosis: a novel pathway in oral, oropharyngeal, hypopharyngeal, and laryngeal cancers

Naunyn-Schmiedeberg s Archives of Pharmacology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 14, 2025

Язык: Английский

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Crosstalk Between Sickle Cell Disease and Ferroptosis

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(8), С. 3675 - 3675

Опубликована: Апрель 13, 2025

Sickle cell disease (SCD) is an inherited hemoglobin disorder that widespread across the globe. It characterized by a very complex pathogenesis, but at basis of mutation HBB gene, which determines production mutated hemoglobin: sickle (HbS). The polymerization HbS, occurs when protein in deoxygenated state, and greater fragility red blood cells (sRBCs) determine release iron, free heme, HbS blood, favoring oxidative stress reactive oxygen species (ROS). These features are common to new model death known as ferroptosis, increase iron ROS concentrations inhibition glutathione peroxidase 4 (GPx4) System Xc−. In this context, review aims discuss potential molecular biochemical pathways ferroptosis involved SCD, aiming highlight possible tags treating inhibiting ferroptosis.

Язык: Английский

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Epigenetic and Post-Translational Modifications in Ferroptosis Regulation and Hepatocellular Carcinoma: New Frontiers in Therapeutic Targeting

Pathology - Research and Practice, Год журнала: 2025, Номер unknown, С. 155991 - 155991

Опубликована: Апрель 1, 2025

Язык: Английский

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Ferroptosis driven by nanoparticles for tackling glioblastoma

Cancer Letters, Год журнала: 2024, Номер unknown, С. 217392 - 217392

Опубликована: Дек. 1, 2024

Язык: Английский

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