Characterization and comparative analysis of antimicrobial resistance in Escherichia coli from hospital and municipal wastewater treatment plants DOI Creative Commons

Gauri Kumar,

Keshava Balakrishna, Chiranjay Mukhopadhyay

и другие.

Journal of Water and Health, Год журнала: 2024, Номер 22(12), С. 2276 - 2288

Опубликована: Ноя. 21, 2024

ABSTRACT The spread of antimicrobial resistance (AMR) poses global health threats, with wastewater treatment plants (WWTPs) as hotspots for its development. Horizontal gene transfer facilitates acquisition genes, particularly through integrons in Escherichia coli. Our study investigates E. coli isolates from hospital and municipal WWTPs, focusing on integrons, their temporal correlation phenotypic molecular characterization AMR. Samples WWTPs were collected over two seasons, pre-monsoon (March–May) post-monsoon (December–February). From the (hWWTP) (mWWTP) influents, 45 172 obtained, respectively. hWWTP exhibited significantly higher rates than mWWTP to most tested antimicrobials except tetracycline. showed a prevalence (86.7%) multidrug (MDR) compared (48.3%). proportion MDR nearly doubled season. Integron positivity was 17.7% 19.7% common cassettes conferring trimethoprim aminoglycosides. Phylogroup analysis predominance group A B1 mWWTP. highlights role disseminating AMR, high class 1 detected.

Язык: Английский

Seasonal assessment of surface water and sediments pollution in Rachiine River, Northern Lebanon, using multivariate statistical analysis DOI Creative Commons

Rosette Mansour,

Jalal Halwani, Mohammad H. El‐Dakdouki

и другие.

Heliyon, Год журнала: 2024, Номер 10(19), С. e39016 - e39016

Опубликована: Окт. 1, 2024

Urbanization has caused severe negative impacts on intra-urban river water worldwide. In this study, the WHO drinking standards (2024) were used as reference to assess physicochemical properties, heavy metals (HMs) content and microbial load in sediment samples collected from 25 locations along Rachiine River, located Northern Lebanon, during wet dry periods. Multivariate statistical analysis was applied evaluate seasonal variations quality, determine pollution sources. The assessment indicated high levels by

Язык: Английский

Процитировано

2
Characterization and comparative analysis of antimicrobial resistance in Escherichia coli from hospital and municipal wastewater treatment plants DOI Creative Commons

Gauri Kumar,

Keshava Balakrishna, Chiranjay Mukhopadhyay

и другие.

Journal of Water and Health, Год журнала: 2024, Номер 22(12), С. 2276 - 2288

Опубликована: Ноя. 21, 2024

ABSTRACT The spread of antimicrobial resistance (AMR) poses global health threats, with wastewater treatment plants (WWTPs) as hotspots for its development. Horizontal gene transfer facilitates acquisition genes, particularly through integrons in Escherichia coli. Our study investigates E. coli isolates from hospital and municipal WWTPs, focusing on integrons, their temporal correlation phenotypic molecular characterization AMR. Samples WWTPs were collected over two seasons, pre-monsoon (March–May) post-monsoon (December–February). From the (hWWTP) (mWWTP) influents, 45 172 obtained, respectively. hWWTP exhibited significantly higher rates than mWWTP to most tested antimicrobials except tetracycline. showed a prevalence (86.7%) multidrug (MDR) compared (48.3%). proportion MDR nearly doubled season. Integron positivity was 17.7% 19.7% common cassettes conferring trimethoprim aminoglycosides. Phylogroup analysis predominance group A B1 mWWTP. highlights role disseminating AMR, high class 1 detected.

Язык: Английский

Процитировано

0