Loss of function of <i>CENH3</i> causes genome instability in soybean DOI Creative Commons
Jing Wang, Xiaofei Wang, Wei‐Cai Yang

и другие.

Seed Biology, Год журнала: 2023, Номер 2(1), С. 0 - 0

Опубликована: Янв. 1, 2023

Centromeres are the site where kinetochores assemble and spindle microtubules anchor to chromosome during cell division. epigenetically specified by centromeric histone H3 (CENH3). The imbalance of CENH3 loading rate or dosage on parental centromeres often leads uniparental elimination in offspring. A body studies genome stability have been reported Arabidopsis, cotton, many other monocots, but not soybean (Glycine max), an important dicot crop. In our study, we identified a single-copy functional CENH3 found its role parent-of-origin effect caused mutation conserved glycine genetic background. This study provide evidence that knockout has potential induce would shed light future development CENH3-based haploid induction (HI) system centromere biology soybean.

Язык: Английский

From gametes to zygote: Mechanistic advances and emerging possibilities in plant reproduction DOI Creative Commons
Sheng Zhong, Peng Zhao, Xiongbo Peng

и другие.

PLANT PHYSIOLOGY, Год журнала: 2024, Номер 195(1), С. 4 - 35

Опубликована: Март 2, 2024

Язык: Английский

Процитировано

8

In vivo Haploid Induction via Parthenogenesis Gene ToPAR in Rice DOI Creative Commons
Jie Xiong, Ya-Jie Ji,

Yang Shenlin

и другие.

Rice Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Perspectives of Genome Editing Mediated Haploid Inducer Systems in Legumes DOI Open Access
Yiqian Liu, Elshan Musazade,

Geng Li

и другие.

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(3), С. 1154 - 1154

Опубликована: Янв. 29, 2025

Genome editing-mediated haploid inducer systems (HISs) present a promising strategy for enhancing breeding efficiency in legume crops, which are vital sustainable agriculture due to their nutritional benefits and ability fix nitrogen. Traditional is often slow complicated by the complexity of legumes’ genomes challenges associated with tissue culture. Recent advancements have broadened applicability HISs facilitating reduction duration cycle. By integrating genome editing technology systems, researchers can achieve precise genetic modifications rapidly produce homozygous lines, thereby significantly accelerating development desired traits. This review explores current status future prospects legumes, emphasizing mechanisms induction; recent breakthroughs; existing technical challenges. Furthermore, we highlight necessity additional research optimize these across various species, has potential greatly enhance contribute sustainability production.

Язык: Английский

Процитировано

0

Widespread application of apomixis in agriculture requires further study of natural apomicts DOI Creative Commons
Charity Z. Goeckeritz, Xixi Zheng,

Alex Harkess

и другие.

iScience, Год журнала: 2024, Номер 27(9), С. 110720 - 110720

Опубликована: Авг. 14, 2024

Apomixis, or asexual reproduction through seeds, is frequent in nature but does not exist any major crop species, yet the phenomenon has captivated researchers for decades given its potential clonal seed production and plant breeding. A discussion on whether this field will benefit from continued study of natural apomicts warranted recent outstanding progress engineering apomixis. Here, we summarize what known about genetic control status applying synthetic apomixis agriculture. We argue there still much to be learned apomicts, learning them necessary improve current guarantee effective application beyond few genera it shown promise so far. Specifically, stress value studying repeated evolution a phylogenetic comparative -omics context. Finally, identify questions discuss how technological advancements can used help close these knowledge gaps. In particular, genomic resources are lacking must remedied widespread use

Язык: Английский

Процитировано

3

Self-propagated clonal seed production in dicotyledonous Arabidopsis DOI
Wen‐Qiang Chen,

Liping Xu,

Yuchun Rao

и другие.

Science Bulletin, Год журнала: 2024, Номер unknown

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

3

Meiosis requires m6A modification for selection of targets in plants DOI Open Access
Cong Wang, Yingxiang Wang

New Phytologist, Год журнала: 2024, Номер unknown

Опубликована: Сен. 2, 2024

'These observations provide evidence that posttranscriptional m6A modification is required for maintaining the activity of meiotic genes, and stage-specific deposition removal ensure orderly progression meiosis.' Meiosis, a specialized form cell division, halves diploid chromosome numbers to generate haploid gametophytes, which essential sexual reproduction in most eukaryotes. Meiotic recombination not only facilitates exchange genetic information between homologous chromosomes (homologs), but also assures their subsequent proper segregation, has great impact on diversity genomic integrity progenies. initiated from programmed formation DSBs, catalyzed by evolutionarily conserved type-II DNA topoisomerase SPO11-1 MTOPVIB complex. The repair DSBs can result homologs known as crossovers (COs) noncrossovers (NCOs) (Wang & Copenhaver, 2018; Zickler Kleckner, 2023). In past 30 years, molecular studies have identified dozens genes involved regulating plants, including some epigenetic factors 2018). However, function RNA related this process largely unknown. Xue et al. made first step towards understanding mechanism eraser ALKBH5 DSB rice meiosis. They started project identifying male sterile mutant gamma-irradiated library. author further cloned target OsALKBH5 gene demonstrated its mutations affected during meiosis I, thus leading sterility. preferentially localizes cytoplasm nucleoplasm pollen mother cells (PMCs), microspores, tapetal cells. confirmed demethylase vitro vivo, mutation impacts modifications stability mRNA Further showed Osalkbh5 displays upmethylated associated downregulated such PAIR2, PAIR3, OsCOM1, OsZIP4, HEIP1, are recombination. These results suggest participates mediating targeted maintain (Fig. 1). Similarly, deficiency mice Alkbh5 homolog resulted increased infertility spermatocytes (Zheng al., 2013). study ALKBH5-mediated erasure mRNAs correct splicing selective degradation long 3′UTR transcripts spermatids (Tang Therefore, may serve fundamental basis shared plants animals, while appear be diversified across different species 2013; Tang As expected, very recent revealed comprehensive maps at single-base precision tissues throughout life cycle both Arabidopsis. Comparative analysis with mammals uncovered existence comparable distribution patterns sites 2024). It been observed expression numerous occurs before initiation maize meiosis, certain exhibit varying levels transcript abundance stages (Nelms Walbot, 2019). mammals, 'writer' Mettl3 'eraser' reported regulate (Xu 2017; By contrast, regulates spermatogonia differentiation initiation, whereas functions spermatogenic round spermatids. Consistently, inactivation METTL3 causes much earlier arrest than Alkbh5-knockout Xu 2017). ensures This conclusion supported finding multiple meiosis-specific regulated OsALKBH5-induced erasure. identification responsible well relationship 'eraser', special targets, needs investigated. al.'s raises other interesting questions. For example, expressed meiocytes tapetum, indicating potential role either tapetum or development. pointed out that, large number unexpected decreased methylation mutant, OsMTOPVIB formation. presents question: how does knockout reduce transcripts. Recent closely correlated factors, methylation, histone modifications, microRNAs, noncoding RNAs, chromatin remodeling (Hu 2024), more complex manner. A tomatoes SlALKBH2 SlDML2 feedback loop fruit ripening (Zhou mammalian cells, H3K36me3 recognized bound directly writer complex, subsequently mark onto actively transcribed RNAs (Huang bidirectional interactions regulators commonly exist among deserves exploration Funding provided Guangdong Laboratory Lingnan Modern Agriculture (NG2022002), National Natural Science Foundation China (Grant Nos. 31925005 32000246), Double first-class discipline promotion SCAU (2023B10564004).

Язык: Английский

Процитировано

0

Microspore embryogenesis: in vitro cultivation induced cell reprogramming for plant breeding DOI
Fan Yang, Xinyu Liu, Ying Qiao

и другие.

Seed Biology, Год журнала: 2020, Номер 0(0), С. 1 - 11

Опубликована: Янв. 1, 2020

Язык: Английский

Процитировано

1

Loss of function of <i>CENH3</i> causes genome instability in soybean DOI Creative Commons
Jing Wang, Xiaofei Wang, Wei‐Cai Yang

и другие.

Seed Biology, Год журнала: 2023, Номер 2(1), С. 0 - 0

Опубликована: Янв. 1, 2023

Centromeres are the site where kinetochores assemble and spindle microtubules anchor to chromosome during cell division. epigenetically specified by centromeric histone H3 (CENH3). The imbalance of CENH3 loading rate or dosage on parental centromeres often leads uniparental elimination in offspring. A body studies genome stability have been reported Arabidopsis, cotton, many other monocots, but not soybean (Glycine max), an important dicot crop. In our study, we identified a single-copy functional CENH3 found its role parent-of-origin effect caused mutation conserved glycine genetic background. This study provide evidence that knockout has potential induce would shed light future development CENH3-based haploid induction (HI) system centromere biology soybean.

Язык: Английский

Процитировано

0