Environment International, Год журнала: 2024, Номер 194, С. 109091 - 109091
Опубликована: Окт. 22, 2024
Язык: Английский
PLoS ONE, Год журнала: 2025, Номер 20(3), С. e0320523 - e0320523
Опубликована: Март 28, 2025
Background Brominated flame retardants (BFRs) are harmful, bioaccumulative, and persistent environmental pollutants, posing significant health risks. Elevated bilirubin levels can cause neurotoxicity damage to the heart, liver, kidneys, other organs. This study utilizes National Health Nutrition Examination Survey (NHANES) data investigate association between exposure BFRs total (TB) in adult participants. Methods Based on from NHANES 2007-2016, TB were divided into tertiles. Spearman’s rank correlation was used analyze relationship individual levels. Weighted linear regression analysis, restricted cubic splines (RCS), stratified analysis conducted assess quantile sum (WQS) quantile-based g-computation (QGC) comprehensively evaluate impact of serum Results The included 5831 results showed that PBB153, PBDE17, PBDE47, PBDE85, PBDE99, PBDE100, PBDE209, PBDE183 significantly correlated with ( p < 0.05), having highest Spearman coefficient 0.292. After adjusting for confounding factors, most BFR remained positively TB, while PBDE153 (β: - 0.031, 95%CI: 0.317, 0.255, = 0.829) PBDE66 0.285, 0.208, 0.777, 0.253) not statistically significant. RCS indicated concentration had a U-shaped PBDE154, PBDE209 an inverted “J”-shaped 0.05). PBDE66, also exhibited nonlinear S-shaped correlations stratification by age gender, WQS QGC mixed 0.553, 0.384, 0.722, 0.001 β: 1.060, 0.587, 1.532, 0.001), contributing most. Conclusions is levels, further suggesting potential humans.
Язык: Английский
Процитировано
0
Frontiers in Cardiovascular Medicine, Год журнала: 2025, Номер 12
Опубликована: Апрель 17, 2025
Hypertension (HTN) is a widespread global health challenge, and its increasing prevalence attributed to individual environmental risk factors. Persistent organic pollutants (POPs), especially polychlorinated biphenyls (PCBs), contribute cardiovascular by accumulating in fatty tissues, which leads oxidative stress vascular inflammation. This review meta-analysis aimed investigate the association between PCB exposure hypertension. Adhering PRISMA 2020 guidelines, data sources such as PubMed, Scopus, Web of Science, Google Scholar were systematically searched up July 2024 find observational studies on link PCBs hypertension risk. Studies reviewed chosen according established inclusion exclusion criteria, focusing examining Independent reviewers conducted extraction, quality was evaluated using JBI critical appraisal tool. A with random-effects model determine combined odds ratios (ORs) for linked total specific types. Of 494 records identified, 21 met comprising 5 cohort studies, 15 cross-sectional one case-control study, totaling 51,514 participants. Exposure correlated an elevated (OR = 1.78, 95% CI: 1.30-2.44). Dioxin-like also associated heightened 1.54, 1.24-1.90), while non-dioxin-like not significantly 1.16, 0.81-1.66). Among congeners, PCB-74, PCB-118, PCB-105, PCB-153 related higher These findings indicate positive correlation hypertension, particularly dioxin-like certain congeners. Additional research necessary clarify mechanisms involved promote measures reducing exposure, high-risk populations. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024595223, PROSPERO (CRD42024595223).
Язык: Английский
Процитировано
0
Reproductive Toxicology, Год журнала: 2025, Номер 135, С. 108938 - 108938
Опубликована: Май 3, 2025
Язык: Английский
Процитировано
0
Microplastics, Год журнала: 2025, Номер 4(2), С. 23 - 23
Опубликована: Май 7, 2025
This review article aims to highlight the potential harm caused by microplastics (MPs) in different organs and systems underscore need for further investigation into their action mechanisms. MPs, such as polystyrene, polypropylene, polyethylene, significantly impact human health, causing inflammation respiratory gastrointestinal systems, compromising immune function, increasing risk of cardiovascular diseases neurotoxicity. These effects are largely attributed role MPs disrupting hormonal regulation, which can lead reproductive disorders an elevated cancer. microscopic particles (less than 5 mm size) now ubiquitous air, water, food. However, much existing research on focuses mechanisms association with health disease, limited emphasis direct humans or long-term consequences. To effectively address plastic toxicity, it is crucial understand policy implications relevance disease development. Recent has highlighted more stringent regulatory oversight these materials better mitigate health.
Язык: Английский
Процитировано
0
Nature Medicine, Год журнала: 2025, Номер 31(5), С. 1431 - 1443
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0
The Journal of School Nursing, Год журнала: 2025, Номер unknown
Опубликована: Май 30, 2025
This study compared the effects of a plastic-free diet program, education and BPA exposure feedback on Bisphenol A levels in adolescents with high use packaged products. As result questionnaires, “high” usage plastic-packaged products “low” attitudes toward healthy eating were assigned to intervention groups simple random sampling method ( n = 108) urinary samples collected. Post-tests conducted after was applied 1, program both Intervention 1 2, 3. All interventions effective reducing levels, decreasing products, improving eating. Implementation implications: (a) training for school nurses stakeholders, (b) families, (c) collaboration (d) enhancing guidance counseling health services.
Язык: Английский
Процитировано
0
Environment International, Год журнала: 2024, Номер 194, С. 109091 - 109091
Опубликована: Окт. 22, 2024
Язык: Английский
Процитировано
2