Pneumo News, Год журнала: 2022, Номер 14(2), С. 42 - 42
Опубликована: Май 1, 2022
International Forum of Allergy & Rhinology, Год журнала: 2023, Номер 13(4), С. 293 - 859
Опубликована: Март 6, 2023
In the 5 years that have passed since publication of 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR-Allergic 2018), literature has expanded substantially. The ICAR-Allergic 2023 update presents 144 individual topics allergic rhinitis (AR), by over 40 from document. Originally presented also been reviewed updated. executive summary highlights key evidence-based findings recommendation full
Язык: Английский
Процитировано
231
Allergologie select, Год журнала: 2024, Номер 8(1), С. 70 - 77
Опубликована: Янв. 1, 2024
Evaluation of a new individual wearable air purifier (Respiray Wear A+) for birch pollen, house dust mite (HDM), and cat-allergic rhinoconjunctivitis (ARC) patients in standardized allergen exposure chamber (AEC).
Язык: Английский
Процитировано
6
The Journal of Allergy and Clinical Immunology In Practice, Год журнала: 2024, Номер 12(6), С. 1399 - 1412
Опубликована: Июнь 1, 2024
Язык: Английский
Процитировано
6
PubMed, Год журнала: 2023, Номер 8(Suppl 4), С. 76 - 102
Опубликована: Сен. 1, 2023
Allergic diseases, especially inhalation allergies, have reached epidemic levels and environmental factors play an important role in their development. Climate change influences the occurrence, frequency, severity of allergic diseases.The contents this article were selected by authors developed section according to expertise current state knowledge. The sections then discussed agreed upon amongst all authors.The highlights direct indirect effects climate on allergies. It goes into detail about connections between (new) pollen allergens as well occupational allergens, explains clinical picture atopic dermatitis, discusses air pollutants provides information phenomenon thunderstorm asthma.There is a need for action field fungal spore monitoring, allergy sensitisation urban planning from allergological perspective, changes working environment, among others.
Язык: Английский
Процитировано
12
Journal of Pediatric Health Care, Год журнала: 2025, Номер unknown
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0
Frontiers in Toxicology, Год журнала: 2023, Номер 5
Опубликована: Авг. 23, 2023
Dry eye disease (DED) is a multifactorial condition that often presents with chronic symptoms of pain (that can be characterized as "dryness," "burning," and "irritation," to name few) and/or fluctuating or poor-quality vision. Given its nature, several pathophysiologic mechanisms have been identified underlie symptoms, including tear film, ocular surface, corneal somatosensory nerve abnormalities. Research has focused on understanding how environmental exposures increase the risk for DED flares negatively impact health. common impacts physical mental functioning, managing requires multiple strategies. These include both medical approaches modulating adverse conditions, latter which may cost-effective way avoid flares. Thus, an relate important. This Review summarizes research relationships between DED, in hope this information will engage healthcare professionals patients consider manipulations their management DED.
Язык: Английский
Процитировано
10
Frontiers in Immunology, Год журнала: 2022, Номер 13
Опубликована: Ноя. 9, 2022
The nasal cavity is an important site of allergen entry. Hence, it represents organ where trans-epithelial penetration and subsequent IgE-mediated allergic inflammation can potentially be inhibited. Intercellular adhesion molecule 1 (ICAM-1) highly expressed on the surface respiratory epithelial cells in patients. It was identified as a promising target to immobilize antibody conjugates bispecific for ICAM-1 allergens thereby block We have previously characterized nanobody specific major birch pollen Bet v here we report generation characterization ICAM-1-specific nanobodies. Nanobodies were obtained from camel immunized with high affinity binder selected after phage display (Nb44). Nb44 recombinant protein containing HA- His-tags Escherichia coli (E.coli) purified via chromatography. SDS-PAGE Western blot revealed single band at approximately 20 kDa. bound ELISA, human bronchial cell line 16HBE14o- determined by flow cytometry. Experiments conducted 4°C 37°C, mimic physiological conditions, yielded similar percentages (97.2 ± 1.2% 96.7 1.5% out total live cells). To confirm visualize binding, performed immunofluorescence microscopy. While Texas Red Dextran rapidly internalized remained localized surface. Additionally, strength interaction using plasmon resonance (SPR). (10 -10 M) had slow off-rates -4 s -1 ). In conclusion, our results showed that not internalized. Thus, could further used engineer heterodimers allergen-specific nanobodies order develop topical treatments allergy.
Язык: Английский
Процитировано
15
AIP Advances, Год журнала: 2024, Номер 14(2)
Опубликована: Фев. 1, 2024
Pollen filters play an essential role in protecting people from airborne allergens and ensuring indoor air quality. Allergic reactions to pollen can lead discomfort, reduced productivity, increased healthcare costs. A low pressure drop of these not only enhances the comfort individuals using but also contributes energy savings ventilation systems, thereby promoting environmental sustainability. This research focuses on shape optimization adjoint solver computational fluid dynamics, aiming enhance both human health In a previous study, approach was developed optimize separation efficiency drop. current work, methodology is presented that exploits findings allows design initial structures, subsequent optimization, detailed experimental numerical comparisons with reference filter example filter. To validate effectiveness optimized filter, geometry were fabricated tested test bench. Compared our disk able separate 2.9% more particles size 6 μm lower by 34.2%. work demonstrates method effectively be used improve performance filters. The results obtained validation suggest exhibits higher while keeping compared state-of-the-art
Язык: Английский
Процитировано
1
Scientific Reports, Год журнала: 2023, Номер 13(1)
Опубликована: Дек. 7, 2023
Abstract It has been shown that pollen information services are an important self-management tool for patients with pollen-related allergic rhinitis (AR) and asthma (AA). This study aimed to design online application AR AA, which supports better manage their disease as well evaluate the app present first results of pilot study. The data were obtained from electronic network Bavaria, Germany. Participants asked fill in allergy-related complaints over a 60-day period. Subsequently, was evaluated. Indices diagrams visualized participants’ individual daily concentration air. In order motivate participants complete on basis, we used elements gamification. Two thirds (N = 46) reported feeling informed about counts allergy when using app. app's simple comprehensible rated positively. More than 80% would recommend family friends. can be AA understand disease.
Язык: Английский
Процитировано
3
Futurity Medicine., Год журнала: 2024, Номер unknown, С. 57 - 67
Опубликована: Май 17, 2024
Aims: To improve existing knowledge in aetiology, diagnosis, management and treatment of allergic respiratory disorders military personnel. The paper also discussed specific treatments, best practices, key sources advances the physical environment for optimal health improvement. Study design: A comprehensive review literature spanning from 2019 to 2024. Methodology: on minimising conditions wounded servicemen utilised PubMed search relevant 2019-2024. Following screening, six studies were chosen 321 records. Results: findings summarised this presented valuable information allergy general among soldiers. research included works with large samples, one which over 20 million members active veterans. Major risks demonstrated environmental factors; 77% participants experienced a contact dermatitis adhesive tapes, 61% colophonium. Accident highlighted, especially factors such as fine particulate matter dust storms. Measures treating involved both pharmacological non-pharmacological methods individual evaluations tests like pulmonary function chest CT scans. All these figures implied need combating issues an effective way within framework groups. Scientific Novelty: This contributed about personnel developed personalised treatment, prevention early diagnostics scale epidemiological data promote combat readiness servicemen. Conclusion: mainly focused problems that are more common personnel; hence accurate allergens identification complex plans. use technology application approaches vital population management, improvement its richness, readiness. Therefore, it is important Military healthcare systems incorporate sound practices correspondingly.
Язык: Английский
Процитировано
0