Diagnosis and treatment of gestational diabetes mellitus DOI Creative Commons
Hyun Sun Ko, Yoon‐Hee Choi

Journal of Korean Medical Association, Год журнала: 2024, Номер 67(11), С. 686 - 694

Опубликована: Ноя. 10, 2024

Background: The increase in obesity and diabetes, coupled with advanced maternal age, has led to an pregnancies affected by hyperglycemia, including gestational diabetes mellitus (GDM), pre-existing early pregnancy hyperglycemia that does not meet the full criteria for diabetes. This surge necessitates better screening management practices mitigate associated fetal risks.Current Concepts: diagnosis of GDM remains challenging owing inconsistent criteria, such as differences oral glucose tolerance test thresholds various strategies diagnosing managing before 20 weeks gestation. Continuous monitoring emerged a promising tool allows comprehensive profile tracking without timing constraints. Additionally, digital health tools, mobile applications, have shown potential supporting control management. These technologies may enable more personalized care improve compliance lifestyle modifications, although evidence is needed establish standardized guidelines their application.Discussion Conclusion: Given increasing number high-risk pregnancies, diagnostic effective protocols are urgently needed. Further research policy initiatives crucial developing prevention, diagnosis, GDM, ultimately reducing its progression postpartum type 2 Digital can be used improving neonatal outcomes, ensuring long-term mothers offspring.

Язык: Английский

Revisiting maternal age and child health: A nationwide birth cohort study in Taiwan DOI Creative Commons

Yi-Yu Su,

Chi‐Jen Chen, Mei‐Huei Chen

и другие.

Journal of the Formosan Medical Association, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Delayed childbearing is a growing trend globally, with Taiwan experiencing one of the steepest increases in maternal age. Advanced age affects offspring health, including birth outcomes and long-term morbidity. However, its impact remains underexplored. This study investigates these effects using nationwide cohort. retrospective cohort utilized data from Taiwan's National Health Insurance Research Database (NHIRD), covering infants born January 1, 2004, to December 31, 2014. The included 2,068,672 infants, categorized into six groups: <20, 20-24, 25-29, 30-34, 35-40, ≥40 years. Principal were stillbirth, mortality, preterm birth, congenital anomalies, neurodevelopmental outcomes, atopic diseases. Multivariate logistic regression models adjusted for covariates assess associations between health outcomes. Among stillbirth mortality rates highest mothers <20 years, decreased increasing age, then rose again ≥30 showing reverse J-shaped pattern. Similar trends noted Atopic diseases followed nonlinear trend, peaking at 25-34 Maternal significantly impacts child risks associated both younger older ages. These findings are crucial regions delayed childbearing. Further research needed explore underlying mechanisms establish causality.

Язык: Английский

Процитировано

0

Global, regional, and national burden of congenital musculoskeletal and limb anomalies, 1990–2021: a systematic analysis of the global burden of disease in 2021 DOI Creative Commons
Yu Luo, Rubin Zheng, Jiaxi Chen

и другие.

Tropical Medicine and Health, Год журнала: 2025, Номер 53(1)

Опубликована: Май 12, 2025

Abstract Background Congenital musculoskeletal and limb (CML) anomalies are uncommon, multifactorial conditions whose global incidence trends remain underexplored. This study delineates the epidemiology temporal evolution of CML from 1990 to 2021. Methods We extracted data 2021 burden disease (GBD) Study, stratifying by sex, region, country socio-demographic index (SDI). calculated age-standardized rate (ASIR), mortality (ASMR), prevalence (ASPR), estimated annual percentage change (EAPC). Decomposition analysis quantified contributions population growth, aging, epidemiological change. Projections 2031 were made using an autoregressive integrated moving average (ARIMA) model. Health inequities assessed via slope inequality (SII) concentration (CI). Results Global patterns exhibited significant disparities between Brunei Darussalam demonstrated highest ASIR, while Afghanistan United Mexican States recorded ASMR ASPR, respectively. Absolute case death burdens predominantly clustered in populous nations, with India China reporting absolute numbers. ARIMA modeling projected a 0.85% increase incident cases (from 2,437,890.12 2,458,596.45), 25.46% decrease 13,599.83 10,137.02), 3.55% 18,549,408.27 19,207,414.19) 2031. analyses revealed that growth was primary driver increased middle SDI regions, whereas transitions aging main contributors reductions. In lower-middle concurrent demographic expansion changes amplified burdens. significantly increased, CI rising 0.28 0.35 0.34 0.42 Significant correlations observed EAPC baseline ASIR/ASMR, declining driven transitions. Conclusion From 2021, anomalies’ divergent across strata, less favorable outcomes lower-SDI countries. Tailored interventions essential mitigate growing these settings.

Язык: Английский

Процитировано

0

Diagnosis and treatment of gestational diabetes mellitus DOI Creative Commons
Hyun Sun Ko, Yoon‐Hee Choi

Journal of Korean Medical Association, Год журнала: 2024, Номер 67(11), С. 686 - 694

Опубликована: Ноя. 10, 2024

Background: The increase in obesity and diabetes, coupled with advanced maternal age, has led to an pregnancies affected by hyperglycemia, including gestational diabetes mellitus (GDM), pre-existing early pregnancy hyperglycemia that does not meet the full criteria for diabetes. This surge necessitates better screening management practices mitigate associated fetal risks.Current Concepts: diagnosis of GDM remains challenging owing inconsistent criteria, such as differences oral glucose tolerance test thresholds various strategies diagnosing managing before 20 weeks gestation. Continuous monitoring emerged a promising tool allows comprehensive profile tracking without timing constraints. Additionally, digital health tools, mobile applications, have shown potential supporting control management. These technologies may enable more personalized care improve compliance lifestyle modifications, although evidence is needed establish standardized guidelines their application.Discussion Conclusion: Given increasing number high-risk pregnancies, diagnostic effective protocols are urgently needed. Further research policy initiatives crucial developing prevention, diagnosis, GDM, ultimately reducing its progression postpartum type 2 Digital can be used improving neonatal outcomes, ensuring long-term mothers offspring.

Язык: Английский

Процитировано

1