The National Sleep Research Resource: towards a sleep data commons

Journal of the American Medical Informatics Association, Год журнала: 2018, Номер 25(10), С. 1351 - 1358

Опубликована: Апрель 26, 2018

The gold standard for diagnosing sleep disorders is polysomnography, which generates extensive data about biophysical changes occurring during sleep. We developed the National Sleep Research Resource (NSRR), a comprehensive system sharing data. NSRR embodies elements of commons aimed at accelerating research to address critical questions impact on important health outcomes.We used metadata-guided approach, with set common sleep-specific terms enforcing uniform semantic interpretation across three main components: (1) annotated datasets; (2) user interfaces accessing data; and (3) computational tools analysis polysomnography recordings. incorporated process managing dataset-specific use agreements, evidence Institutional Review Board review, corresponding access control in web portal. approach facilitates structural interoperability, ultimately leading enhanced reusability scientific rigor.The authors curated deposited retrospective from 10 large, NIH-funded cohort studies, including several Trans-Omics Precision Medicine (TOPMed) program, into NSRR. currently contains 26 808 subjects 31 166 signal files European Data Format. Launched April 2014, over 3000 registered users have downloaded 130 terabytes data.The offers case an example creating full-fledged commons. It provides single point analysis-ready physiological signals obtained multiple sources, wide variety clinical facilitate research.

Язык: Английский

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Use of Actigraphy for the Evaluation of Sleep Disorders and Circadian Rhythm Sleep-Wake Disorders: An American Academy of Sleep Medicine Systematic Review, Meta-Analysis, and GRADE Assessment

Journal of Clinical Sleep Medicine, Год журнала: 2018, Номер 14(07), С. 1209 - 1230

Опубликована: Июль 13, 2018

The purpose of this systematic review is to provide supporting evidence for a clinical practice guideline on the use actigraphy.The American Academy Sleep Medicine commissioned task force experts in sleep medicine. A was conducted identify studies that compared actigraphy, logs, and/or polysomnography. Statistical analyses were performed determine significance using actigraphy as an objective measure and circadian parameters. Finally, Grading Recommendations Assessment, Development, Evaluation (GRADE) process used assess making recommendations.The literature search resulted 81 met inclusion criteria; all provided data suitable statistical analyses. These demonstrate provides consistent often unique from patient-reported logs some parameters adult pediatric patients with suspected or diagnosed insomnia, rhythm sleep-wake disorders, sleep-disordered breathing, central disorders hypersomnolence, adults insufficient syndrome. also not reliable periodic limb movements patients. detailed summary along quality evidence, balance benefits harms, patient values preferences, resource considerations.

Язык: Английский

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Comparison of Self-Reported Sleep Duration With Actigraphy: Results From the Hispanic Community Health Study/Study of Latinos Sueño Ancillary Study

American Journal of Epidemiology, Год журнала: 2016, Номер 183(6), С. 561 - 573

Опубликована: Март 2, 2016

Most studies of sleep and health outcomes rely on self-reported duration, although correlation with objective measures is poor. In this study, we defined sociodemographic characteristics associated misreporting assessed whether accounting for these factors better explains variation in duration among 2,086 participants the Hispanic Community Health Study/Study Latinos who completed more than 5 nights wrist actigraphy reported habitual bed/wake times from 2010 to 2013. Using linear regression, examined self-report as a predictor actigraphy-assessed duration. Mean amount time spent asleep was 7.85 (standard deviation, 1.12) hours by 6.74 1.02) actigraphy; between them 0.43. For each additional hour sleep, increased 20 minutes (95% confidence interval: 19, 22). Correlations were lower male sex, younger age, efficiency <85%, night-to-night variability ≥1.5 hours. Adding self-reports proportion variance explained slightly (18%-32%). large validation study including Hispanics/Latinos, demonstrated moderate asleep. The performance varied demographic but not subgroup.

Язык: Английский

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Sleep Irregularity and Subclinical Markers of Cardiovascular Disease: The Multi‐Ethnic Study of Atherosclerosis

Journal of the American Heart Association, Год журнала: 2023, Номер 12(4)

Опубликована: Фев. 21, 2023

Background Sleep irregularity has been linked to incident cardiovascular disease. Less is known about associations of sleep regularity with atherosclerosis. We examined cross‐sectional actigraphy‐assessed duration and timing subclinical atherosclerosis in the community‐based MESA (Multi‐Ethnic Study Atherosclerosis). Methods Results Ancillary participants (N=2032; mean age, 68.6±9.2 years; 37.9% White) completed 7‐day wrist actigraphy. Participants underwent assessments coronary artery calcium, carotid plaque presence, intima‐media thickness, ankle‐brachial index. was quantified by with‐in person SD onset timing. Relative risk regression models were used calculate prevalence ratios 95% CIs. Models are adjusted for demographics, disease factors, other objectively assessed characteristics including obstructive apnea, duration, fragmentation. After adjustment, compared more regular durations (SD ≤60 minutes), greater >120 minutes) likely have high calcium burden (>300; ratio, 1.33 [95% CI, 1.03–1.71]) abnormal index (<0.9; 1.75 1.03–2.95]). Compared ≤30 irregular >90 (prevalence 1.39 1.07–1.82]). Associations persisted after adjustment factors average Conclusions irregularity, particularly associated several measures may be a modifiable target reducing risk. Future investigation into reduction interventions targeting warranted.

Язык: Английский

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Practical considerations in using accelerometers to assess physical activity, sedentary behavior, and sleep

Sleep Health, Год журнала: 2015, Номер 1(4), С. 275 - 284

Опубликована: Окт. 23, 2015

Язык: Английский

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Benchmark on a large cohort for sleep-wake classification with machine learning techniques

npj Digital Medicine, Год журнала: 2019, Номер 2(1)

Опубликована: Июнь 7, 2019

Accurately measuring sleep and its quality with polysomnography (PSG) is an expensive task. Actigraphy, alternative, has been proven cheap relatively accurate. However, the largest experiments conducted to date, have had only hundreds of participants. In this work, we processed data recently published Multi-Ethnic Study Atherosclerosis (MESA) Sleep study both PSG actigraphy synchronized. We propose adoption publicly available large dataset, which at least one order magnitude larger than any other systematically compare existing methods for detection sleep-wake stages, thus fostering creation new algorithms. also implemented compared state-of-the-art score range from widely used traditional algorithms recent machine learning approaches. identified among algorithms, two approaches that perform better algorithm by device in MESA experiments. The performance, regards accuracy F1 was superior device's native comparable human annotation. Future research developing scoring particular, approaches, will be highly facilitated cohort here. exemplify potential showing particular deep-learning architectures, CNN LSTM, many created, can achieve scores significantly higher same tasks.

Язык: Английский

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Sleep Patterns and Hypertension Using Actigraphy in the Hispanic Community Health Study/Study of Latinos

CHEST Journal, Год журнала: 2017, Номер 153(1), С. 87 - 93

Опубликована: Сен. 30, 2017

Язык: Английский

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Sleep During Pregnancy: The nuMoM2b Pregnancy and Sleep Duration and Continuity Study

SLEEP, Год журнала: 2017, Номер 40(5)

Опубликована: Март 24, 2017

To characterize sleep duration, timing and continuity measures in pregnancy their association with key demographic variables. Multisite prospective cohort study. Women enrolled the nuMoM2b study (nulliparous women a singleton gestation) were recruited at second visit (16–21 weeks of to participate Sleep Duration Continuity substudy. <18 years age or pregestational diabetes chronic hypertension excluded from participation. wore wrist activity monitor completed log for 7 consecutive days. Time bed, fragmentation index, efficiency, wake after onset, midpoint averaged across valid primary periods each participant. Valid data available 782 mean 27.3 (5.5) years. Median duration was 7.4 hours. Approximately 27.9% had <7 hours; 2.6% >9 In multivariable models including age, race/ethnicity, body mass insurance status, recent smoking history, significantly associated race/ethnicity while time bed only status. all covariates model, exception index onset. Our results demonstrate relationship between important characteristics during pregnancy.

Язык: Английский

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Neighborhood Factors as Predictors of Poor Sleep in the Sueño Ancillary Study of the Hispanic Community Health Study/Study of Latinos

SLEEP, Год журнала: 2016, Номер 40(1)

Опубликована: Дек. 9, 2016

To evaluate whether an adverse neighborhood environment has higher prevalence of poor sleep in a US Hispanic/Latino population. A cross-sectional analysis was performed 2156 participants aged 18–64 years from the Sueño ancillary study Hispanic Community Health Study/Study Latinos (HCHS/SOL). Participants completed surveys including perceived safety, violence and noise, Insomnia Severity Index (ISI), 7 days wrist actigraphy. In age sex-adjusted analyses, short sleep, low efficiency, late midpoint were all more prevalent among those living unsafe neighborhood. After adjustment for background, site, nativity, income, employment, depressive symptoms, apnea, absolute risk sleeping <6 hours 7.7 (95% CI [0.9, 14.6]) percentage points greater compared to safe There no differences insomnia by level safety or violence. noisy adjusted analysis, 4.4 [0.4, 8.4]) non-noisy neighborhoods. Using validated measures duration insomnia, we have demonstrated existence factors. An is established factor variety health outcomes. Our findings suggest negative effects on may represent one pathway which influences health.

Язык: Английский

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Prevalence of sleep disturbances: Sleep disordered breathing, short sleep duration, and non-restorative sleep

Respiratory Investigation, Год журнала: 2019, Номер 57(3), С. 227 - 237

Опубликована: Март 2, 2019

Язык: Английский

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