Journal of Organometallic Chemistry, Год журнала: 2021, Номер 948, С. 121912 - 121912
Опубликована: Май 31, 2021
Язык: Английский
Journal of Organometallic Chemistry, Год журнала: 2021, Номер 948, С. 121912 - 121912
Опубликована: Май 31, 2021
Язык: Английский
Tetrahedron Letters, Год журнала: 2013, Номер 54(11), С. 1478 - 1481
Опубликована: Янв. 16, 2013
Язык: Английский
Процитировано
13Heliyon, Год журнала: 2024, Номер 10(22), С. e40373 - e40373
Опубликована: Ноя. 1, 2024
This research dealt with the green methods to react levofloxacin (LF) dicarboxylate acids: oxalic acid (OX), succinic (SA), malonic (MN), and maleic (MA) investigated its impact on LF's stability, solubility, antimicrobial potency, which never been reported before. Solvent-dropped grinding (SDG) using ethanol 95 % was used prepare organic antibiotic salts, reducing solvent usage significantly compared conventional evaporation method, supported solid-state characterization electrothermal, differential scanning calorimetry powder X-ray diffractometry. Next, Fourier Transform Infrared Spectroscopy Nuclear Magnetic Resonance (1H-NMR) confirmed determined interaction structure between LF acids. Afterward, benefits of LF-dicarboxylate salts were investigated, including potency. The results demonstrated that SDG could produce LF-OX hydrate, LF-SA anhydrous LF-MN in a (1:1) molar ratio, diffractogram yet explained. Meanwhile, LF-MA salt identical one. Notably, these LF-dicarboxylates showed better potency than alone, suggesting potential for further dosage formulations.
Язык: Английский
Процитировано
1Photochemical & Photobiological Sciences, Год журнала: 2015, Номер 14(4), С. 833 - 841
Опубликована: Фев. 13, 2015
Язык: Английский
Процитировано
11Tetrahedron Letters, Год журнала: 2014, Номер 55(40), С. 5458 - 5461
Опубликована: Авг. 8, 2014
Язык: Английский
Процитировано
9Journal of Organometallic Chemistry, Год журнала: 2021, Номер 948, С. 121912 - 121912
Опубликована: Май 31, 2021
Язык: Английский
Процитировано
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