Current Drug Targets,
Год журнала:
2024,
Номер
25(13), С. 847 - 865
Опубликована: Авг. 22, 2024
Phytochemicals,
the
bioactive
compounds
in
plants,
possess
therapeutic
benefits,
such
as
antimicrobial,
antioxidant,
and
pharmacological
activities.
However,
their
clinical
use
is
often
hindered
by
poor
bioavailability
stability.
Phytosome
technology
enhances
absorption
efficacy
of
these
integrating
vesicular
systems
like
liposomes,
niosomes,
transfersomes,
ethosomes.
Phytosomes
offer
diverse
biological
including
cardiovascular
protection
through
improved
endothelial
function
oxidative
stress
reduction.
They
enhance
cognitive
protect
against
neurodegenerative
diseases
nervous
system,
aid
digestion
reduce
inflammation
gastrointestinal
provide
hepatoprotective
effects
enhancing
liver
detoxification
toxins.
In
genitourinary
phytosomes
improve
renal
exhibit
anti-inflammatory
properties.
also
modulate
immune
system
responses
reducing
stress.
Additionally,
promote
skin
health
protecting
UV
radiation
improving
hydration
elasticity.
Recent
patented
phytosome
technologies
have
led
to
innovative
formulations
that
stability,
bioavailability,
phytochemicals,
although
commercialization
challenges
manufacturing
scalability
regulatory
hurdles
remain.
Secondary
metabolites
from
natural
products
are
classified
into
primary
secondary
metabolites,
with
a
significant
focus
on
terpenoids,
phenolic
compounds,
nitrogen-containing
compounds.
These
notable
activities:
antibiotic,
antiviral,
anti-inflammatory,
anticancer
effects.
summary,
this
review
amalgamates
latest
advancements
metabolite
research,
presenting
holistic
view
potential
advance
interventions
contribute
ever-evolving
landscape
product-based
medicine.
Pharmaceuticals,
Год журнала:
2024,
Номер
17(6), С. 772 - 772
Опубликована: Июнь 13, 2024
The
emergence
of
antibiotic
resistance,
caused
by
the
improper
use
antibiotics,
is
a
significant
challenge
in
combating
infectious
diseases,
leading
to
millions
annual
fatalities.
occurrence
antimicrobial
side
effects
catalyzes
investigation
novel
compounds
and
sources
drugs.
Consequently,
research
on
biological
activity
that
conducted
plants,
plant
extracts,
are
produced
from
components
utmost
significance.
In
this
study,
CtAC/MNPs
were
obtained
reaction
activated
carbon
(AC)
fruits
Celtis
tournefortii
(Ct)
magnetic
nanoparticles
(MNPs),
CtAC/MNPs-Ag
nanocomposite
was
synthesized
reduction
silver
ions
added
reaction.
nanocomposites
analyzed
spectroscopically
(FTIR,
XRD),
microscopically
(SEM,
EDX),
optically
(DLS),
electrochemically
(zeta
potential)
magnetically
(VSM).
antibacterial
activities
against
S.
aureus
E.
coli
investigated
microdilution
method
using
minimal
inhibitory
concentration
(MIC)
disk
diffusion
methods.
Antioxidant
including
total
phenolic
content
DPPH
cuprac
assays,
revealed
remarkable
effect
nanocomposite.
This
study
has
advantages
obtaining
short
time
without
requiring
energy,
most
importantly,
takes
place
any
toxic
substances.
addition,
according
data
thought
shed
light
biomedical
research.
Results in Chemistry,
Год журнала:
2024,
Номер
10, С. 101682 - 101682
Опубликована: Июль 27, 2024
The
multipurpose
properties
of
mixed
metal
oxides
have
garnered
significant
interest.
This
study's
ternary
composite
MnO2/CuO/ZrO2
(MCZ)
exhibited
promising
morphology,
conductivity
and
electrochemical
performance.
MCZ
nanocomposite
was
synthesized
via
hydrothermal
methods.
impact
electrolytes
like
Potassium
hydroxide
(KOH)
on
supercapacitor
features
investigated.
XRD
analysis
determined
the
crystalline
structure,
while
FTIR
confirmed
presence
Cu–O,
O-Mn–O
Zr–O
bonds.
SEM
revealed
uniform
aggregated
particles,
EDAX
elemental
composition.
BET
measured
pore
radius
surface
area.
With
a
1
M
KOH
electrolyte,
performance
evaluated
using
CV,
GCD,
EIS.
electrode
specific
capacitance
869.76
F/g
at
scan
rate
5
mV/s.
symmetric
device
showed
an
energy
density
213.09
Wh/kg
power
3.83
kW/kg,
maintaining
cycling
stability
after
5000
cycles.
displayed
high
ionization
in
solvent,
facilitating
efficient
ion
movement
for
charge
transfer
supercapacitors.
nanocomposite's
areal-specific
119.04
mF/cm2,
with
areal
densities
0.081
mWh/cm2
1.3885
mW/cm2,
respectively.
Increasing
area
materials
enhances
storage
capacity.
study
suggests
that
can
improve
Journal of Translational Medicine,
Год журнала:
2024,
Номер
22(1)
Опубликована: Ноя. 8, 2024
The
complexity
of
tumors
and
the
challenges
associated
with
treatment
often
stem
from
limitations
existing
models
in
accurately
replicating
authentic
tumors.
Recently,
organoid
technology
has
emerged
as
an
innovative
platform
for
tumor
research.
This
bioengineering
approach
enables
researchers
to
simulate,
vitro,
interactions
between
their
microenvironment,
thereby
enhancing
intricate
interplay
cells
surroundings.
Organoids
also
integrate
multidimensional
data,
providing
a
novel
paradigm
understanding
development
progression
while
facilitating
precision
therapy.
Furthermore,
advancements
imaging
genetic
editing
techniques
have
significantly
augmented
potential
organoids
review
explores
application
more
precise
simulations
its
specific
contributions
cancer
research
advancements.
Additionally,
we
discuss
evolving
trends
developing
comprehensive
utilizing
technology.
This
study
investigates
the
transformative
potential
of
mushroom-derived
biomaterials
within
biomedical
engineering,
presenting
them
as
sustainable
and
eco-friendly
alternatives
to
conventional
materials.
By
examining
distinct
characteristics
chemical
compositions
various
mushroom
species,
we
highlight
their
suitability
for
creating
innovative
biomaterials.
The
paper
focuses
on
key
components,
such
polysaccharides,
fungal
mycelium,
chitin/chitosan,
demonstrating
applications
in
tissue
antimicrobial
treatments,
drug
delivery
systems.
biodegradability
cultivation
mushrooms
underscore
environmental
advantages,
aligning
with
global
sustainability
goals.
Through
detailed
case
studies,
illustrate
successful
these
medical
devices,
construction,
packaging,
showcasing
versatility
effectiveness.
also
addresses
current
challenges
proposes
future
research
directions,
emphasizing
need
interdisciplinary
collaboration
ensure
safety,
biocompatibility,
ethical
use
mushroom-based
Our
provides
a
comprehensive
roadmap
harnessing
materials,
paving
way
significant
advancements
devices
contributing
more
future.
We
have
demonstrated
that
are
promising
frontier
material
science,
revolutionize
field
contribute
environment.
