IntechOpen eBooks, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 4, 2024

Precision medicine has revolutionized the approach to breast cancer treatment by leveraging molecular subtyping, biomarker identification, genomic profiling, and targeted therapies. This comprehensive review explores significance of subtypes—Luminal A, Luminal B, HER2+, triple-negative—and their respective characteristics prognoses. It discusses pivotal role biomarkers such as HER2, estrogen receptors (ER), progesterone (PR) in predicting prognosis therapy response. The delves into advanced profiling techniques, including next-generation sequencing (NGS) fluorescence situ hybridization (FISH), implications for personalized plans. Furthermore, it highlights potential liquid biopsies circulating tumor DNA (ctDNA) non-invasive diagnostics monitoring. integration machine learning artificial intelligence predictive modeling algorithms is examined, along with challenges posed heterogeneity access testing. Future prospects, expansion CRISPR-based technologies learning, are also discussed. Finally, strategies integrating precision clinical practice future innovations field highlighted, emphasizing importance collaboration, patient education, shared decision-making.

Язык: Английский