Vanishing twins, selection in utero, and infant mortality in the United States
Evolution Medicine and Public Health,
Год журнала:
2025,
Номер
13(1), С. 5 - 13
Опубликована: Янв. 1, 2025
ABSTRACT
Background
and
Objectives
Research
to
identify
fetal
predictors
of
infant
mortality
among
singletons
born
in
the
United
States
(US)
concludes
that
poorly
understood
unmeasured
“confounders”
produce
a
spurious
association
between
size
death.
We
argue
these
confounders
include
Vanishing
Twin
Syndrome
(VTS)—the
clinical
manifestation
selection
against
frail
male
twins
utero.
test
our
argument
276
monthly
conception
cohorts
conceived
US
from
January
1995
through
December
2017.
Methodology
use
Box-Jenkins
transfer
function
modeling
hypothesis
infants
2017,
sex
ratio
37th
week
gestation
will
correlate
inversely
with
singleton
males
at
40th
gestation.
Results
find
support
for
infer
contribution
survivors
VTS
temporal
variation
hardiest
infants,
those
40
weeks
gestation,
ranged
decrease
about
7%
an
increase
5%
over
cohorts.
Conclusions
Implications
conclude
evolutionary
perspective
on
loss
makes
heretofore
“unmeasured
confounder”
relationship
both
explicable
measurable.
This
finding
may
help
clinicians
better
anticipate
changes
time
incidence
mortality.
Язык: Английский
sCEACAM-1 levels in maternal blood in case of threatened preterm birth
European Journal of Obstetrics & Gynecology and Reproductive Biology,
Год журнала:
2025,
Номер
307, С. 230 - 235
Опубликована: Фев. 14, 2025
Язык: Английский
Call to include breastfeeding as a synergistic approach to vaccines for prevention of respiratory syncytial virus disease
International Breastfeeding Journal,
Год журнала:
2025,
Номер
20(1)
Опубликована: Март 3, 2025
Abstract
Background
Infections
with
respiratory
syncytial
virus
(RSV)
in
infancy
and
early
childhood
are
very
common.
RSV
is
the
leading
cause
of
bronchiolitis
pneumonia
substantially
contributes
to
morbidity
mortality
infants
young
children
worldwide.
Until
recently,
there
have
been
no
vaccines
available
for
prevention
curative
treatments
RSV.
Two
novel
pharmaceutical
approaches
became
2024
namely
immunization
mothers
during
pregnancy
immunoprophylaxis
infants.
Since
then,
a
series
scientific
papers
as
well
national
international
guidance
published
encourage
parents
vaccinate
themselves
or
their
children.
Despite
strong
evidence
that
breastfeeding
an
important
non-pharmacological
approach
severe
outcomes,
recent
public
health
communications
neglected
core
RSV-preventive
strategy.
This
commentary
highlights
epidemiological
protective
effects
key
intervention,
discussing
its
synergistic
role
supportive
care
sick
Breastfeeding
has
shown
reduce
rate
severity
RSV-associated
including
hospitalization
mortality.
While
exclusive
most
protective,
even
one
month
was
associated
reduced
likelihood
Intensive
Care
Unit
admission
need
mechanical
ventilation
RSV-infected
The
benefits
demonstrated
studies
low-,
middle-
high-income
settings
especially
small,
premature
Conclusion
overlooked
sustainable
strategy
universal
outcomes
serves
disease
infancy,
vulnerable
population
groups.
should
be
encouraged
alongside
all
communication,
by
providers
pre-
postnatal
visits
infant
check-ups.
Further,
critically-ill
not
overlooked.
Язык: Английский
Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021
Frontiers in Medicine,
Год журнала:
2025,
Номер
12
Опубликована: Апрель 4, 2025
Background
Neonatal
infections,
particularly
neonatal
sepsis,
remain
significant
contributors
to
morbidity
and
mortality
in
pediatrics.
This
study
aims
provide
data
support
for
health
authorities
control
infections
by
analyzing
the
burden
of
sepsis
other
infectious
(NSNIs)
globally
trends
their
risk
factors.
Methods
is
based
on
Global
Burden
Disease
(GBD)
database,
reviewing
diseases
from
1990
2021
at
global,
regional,
national
levels.
Descriptive
statistics
Joinpoint
regression
analyses
were
employed
assess
incidence
rates,
prevalence
Disability-Adjusted
Life
Years
(DALYs),
with
Average
Annual
Percent
Change
(AAPC)
used
quantify
these
trends.
Results
The
findings
reveal
that
2021,
global
(AAPC
=
−0.8%,
p
<
0.01),
DALYs
−0.9%,
rates
0.01)
showed
a
downward
trend.
was
notably
higher
males
than
females.
Regional
analysis
indicated
disease
remains
high
Africa
Southeast
Asia,
367,540.10/100,000
180,599.79/100,000,
respectively.
Conversely,
Eastern
Mediterranean
Western
Pacific
regions
has
been
rising,
increasing
53,165.45/100,000
2016
57,179.59/100,000
125,896.44/100,000
2018
131,698.77/100,000
2021.
National-level
revealed
Sierra
Leone,
Chad,
Burkina
Faso
had
significantly
burdens
compared
countries,
534,090.25/100,000,
520,317.08/100,000,
505,365.73/100,000
An
factors
associated
ambient
particulate
matter
pollution
increased
0.7%
since
1990,
while
Household
air
solid
fuels
decreased
1.4%.
Although
related
low
birth
weight
short
gestation
declined
many
an
upward
trend
observed
(DALYs
88,653.41/100,000
93,752.24/100,000
28,813.84/100,000
2017
32,280.55/100,000
Pacific).
Conclusion
indicates
NSNIs
decreased,
situation
serious
continuing
rise
recent
years.
Policymakers
should
prioritize
improving
healthcare
facilities,
access
medical
resources,
investing
maternal
care
effectively
reduce
NSNIs.
Язык: Английский
Birth weight and school absences and attainment: a longitudinal linked cohort study of compulsory schooling in England
Archives of Disease in Childhood,
Год журнала:
2025,
Номер
unknown, С. archdischild - 328611
Опубликована: Апрель 25, 2025
Objective
To
explore
how
birth
weight
and
size-for-gestation
may
contribute
to
school
absences
educational
attainment
whether
there
are
different
associations
across
sex
income
groups.
Design
Longitudinal
linked
cohort
study.
Methods
Data
were
drawn
from
the
Millennium
Cohort
Study,
a
nationally
representative
of
children
born
in
2000–2001;
percentage
authorised
unauthorised
Year
1
11,
Key
Stage
test
scores
at
ages
7,
11
16
English
Maths
National
Pupil
Database.
Birth
outcomes
covariates
derived
9-month
survey,
linear
regressions
with
complex
survey
weights
fitted.
Results
Being
small-for-gestational-age
(vs
average-for-gestational-age)
was
associated
an
increase
0.47%,
0.55%
0.40%
Years
1,
3
4
(n=6659)
reduction
0.16–0.26
SD
all
(n=6204).
Similar
found
for
weight.
After
adjusting
prior
scores,
(b=0.07)
(b=0.05)
performance
age
remained
Socioeconomic
status
modified
associations:
larger
disparities
among
higher-income
families,
suggesting
that
higher
did
not
compensate
being
small-for-gestational-age.
Conclusion
Children
smaller
missed
slightly
more
classes
(~1
day
per
year)
during
primary
had
lower
compulsory
education.
Exploring
specific
health
conditions
understanding
education
systems
can
work
together
support
help
reduce
burden.
Язык: Английский
Descriptive analysis of risk factors for preterm infants with birth weight
Journal of Nursing, Education Sciences, and Medical Practice. /$c Fatima Zohra Rezouki,
Год журнала:
2024,
Номер
1(1), С. 13 - 20
Опубликована: Дек. 12, 2024
Introduction:
Prematurity
is
defined
as
a
birth
occurring
before
the
37th
week
of
amenorrhea,
calculated
from
1st
day
last
menstrual
period
and/or
an
ultrasound
scan
performed
during
first
trimester
pregnancy.
Premature
continues
to
be
world's
leading
cause
infant
and
child
mortality,
sensorimotor
disability,
neurodevelopmental
difficulties.
Objective:
Our
work
aims
describe
incidence
risk
factors
prematurity
compare
our
results
with
those
other
studies.
Materials
methods:
This
cross-sectional,
retrospective,
descriptive
study
conducted
over
two
years,
June
1,
2021,
30,
2023,
at
neonatology
neonatal
intensive
care
unit
CHU
HASSAN
II
in
Fez.
Statistical
analyses
were
using
JAMOVI
software.
Qualitative
variables
expressed
frequencies
percentages,
while
quantitative
presented
means
standard
deviations
(SD)
or
medians
interquartile
ranges
(IQR).
Results:
The
resuscitation
department
welcomed
241
premature
newborns
weight
≤
1500g,
representing
8.80%
all
hospitalizations
department.
127
(53%)
female,
114
(47%)
male.
mean
gestational
age
was
30.6
±
2.4
weeks
amenorrhea.
71%
(170)
born
spontaneously
preterm,
29%
(71)
induced
preterm.
Factors
associated
mainly
threat
preterm
delivery
(36%),
lack
medical
follow-up
pregnancy
(21%),
gravidic
hypertension
18.67%,
diabetes
5.80%
cases.
Conclusion:
determined
frequency
identified
certain
factors,
some
which
are
already
targeted
by
national
perinatal
program.
intended
sound
alarm
about
need
implement
management
plan
improve
monitoring
pregnancies
births
levels
care.
Язык: Английский