Microbiome of pregnancy (literature review)
Vestnik ohrany materinstva i mladenčestva.,
Год журнала:
2025,
Номер
1(3), С. 25 - 41
Опубликована: Янв. 14, 2025
Background.
Pregnancy
represents
a
unique
immunological
and
physiological
period
during
which
microbial
communities
can
have
significant
impact
on
both
maternal
health
birth
outcomes.
Hormonal,
immunological,
metabolic
changes
pregnancy
influence
the
microbiome
clinical
outcomes,
potentially
impacting
well-being
of
mother
child.
Objective:
generalization
modern
scientific
concepts
about
relationship
between
composition
mother’s
microbiota
its
complications,
discussion
possibility
predicting
complications
using
microbiome.
Materials
methods.
An
extensive
literature
review
was
conducted
MEDLINE
(PubMed)
database
as
December
2024
with
following
keywords
filter:
randomized
controlled
trial,
meta-analysis,
systematic
review.
Research
results:
Extensive
research
links
dominance
certain
Lactobacillus
strains
to
different
L.
cripatus
being
most
favorable
strain.
Only
by
existing
in
normal
symbiotic
organism
is
it
possible
maintain
homeostasis.
Any
shift
balance
this
system
leads
growth
opportunistic
flora,
turn
triggers
cascade
disorders.
GDM,
PCOS,
premature
—
these
conditions
features
vaginal
microbiocenosis.
Conclusion.
The
female
reproductive
tract
intestine
dynamic
influenced
number
factors.
More
evidence
suggests
that
dysbiosis
associated
various
adverse
Knowledge
has
potential
improve
accuracy
diagnosis,
develop
targeted
interventions,
reduce
risk
perinatal
complications.
Язык: Английский
Resilience to Global Health Challenges Through Nutritional Gut Microbiome Modulation
Nutrients,
Год журнала:
2025,
Номер
17(3), С. 396 - 396
Опубликована: Янв. 22, 2025
As
the
world
faces
an
escalating
challenge
of
non-communicable
diseases
(NCDs),
with
phenotypes
ranging
from
allergic
chronic
immuno-inflammatory
to
neuropsychiatric
disorders,
it
becomes
evident
that
their
seeds
are
sown
during
early
stages
life.
Furthermore,
within
only
a
few
decades,
human
obesity
has
reached
epidemic
proportions
and
now
represents
most
serious
public
health
our
time.
Recent
demonstrations
growing
number
these
conditions
linked
aberrant
gut
microbiota
composition
function
have
evoked
active
scientific
interest
in
host-microbe
crosstalk,
characterizing
modulating
at-risk
circumstances.
These
efforts
appear
particularly
justified
critical
period
developmental
plasticity
when
child’s
immune,
metabolic,
microbiological
constitutions
lend
themselves
long-term
adjustment.
Pregnancy
infancy
epitomize
ideal
juncture
for
preventive
measures
aiming
reduce
risk
NCDs;
by
promoting
pregnant
lactating
women
today,
next
generation(s)
may
be
successfully
improved.
The
perfect
tools
this
initiative
derive
earliest
massive
source
environmental
exposures,
namely
microbiome
nutrition,
due
fundamental
interactions
host
immune
metabolic
maturation.
Язык: Английский
Mikrobiom im Fokus: Braucht es einen Paradigmenwechsel in der Geburtshilfe?
Hebamme,
Год журнала:
2025,
Номер
38(01), С. 25 - 33
Опубликована: Фев. 1, 2025
Healthy food design based on gut microbiota metabolic flux
Trends in Food Science & Technology,
Год журнала:
2024,
Номер
154, С. 104790 - 104790
Опубликована: Ноя. 12, 2024
Язык: Английский
Nutraceuticals as Modulators of Molecular Placental Pathways: Their Potential to Prevent and Support the Treatment of Preeclampsia
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(22), С. 12167 - 12167
Опубликована: Ноя. 13, 2024
Preeclampsia
(PE)
is
a
serious
condition
characterized
by
new-onset
hypertension
and
proteinuria
or
organ
dysfunction
after
the
20th
week
of
gestation,
making
it
leading
cause
maternal
fetal
mortality
worldwide.
Despite
extensive
research,
significant
gaps
remain
in
understanding
mechanisms
underlying
PE,
contributing
to
ineffectiveness
current
prevention
treatment
strategies.
Consequently,
premature
cesarean
sections
often
become
primary
intervention
safeguard
health.
Emerging
evidence
indicates
that
placental
insufficiency,
driven
molecular
disturbances,
plays
central
role
development
PE.
Additionally,
microbiome
may
be
implicated
pathomechanism
preeclampsia
secreting
metabolites
influence
inflammation
oxidative
stress,
thereby
affecting
Given
limitations
pharmaceuticals
during
pregnancy
due
potential
risks
concerns
about
teratogenic
effects,
nutraceuticals
provide
safer
alternatives.
Nutraceuticals
are
food
products
dietary
supplements
offer
health
benefits
beyond
basic
nutrition,
including
plant
extracts
probiotics.
Their
historical
use
traditional
medicine
has
provided
valuable
insights
into
their
safety
efficacy,
for
pregnant
women.
This
review
will
examine
how
adoption
can
enhance
dysregulated
pathways,
potentially
offering
preeclampsia.
Язык: Английский