The Influence of Cecal Microbiota Transplantation on Chicken Injurious Behavior: Perspective in Human Neuropsychiatric Research
Biomolecules,
Год журнала:
2024,
Номер
14(8), С. 1017 - 1017
Опубликована: Авг. 16, 2024
Numerous
studies
have
evidenced
that
neuropsychiatric
disorders
(mental
illness
and
emotional
disturbances)
with
aggression
(or
violence)
pose
a
significant
challenge
to
public
health
contribute
substantial
economic
burden
worldwide.
Especially,
social
disorganization
inequality)
associated
childhood
adversity
has
long-lasting
effects
on
mental
health,
increasing
the
risk
of
developing
disorders.
Intestinal
bacteria,
functionally
as
an
endocrine
organ
second
brain,
release
various
immunomodulators
bioactive
compounds
directly
or
indirectly
regulating
host’s
physiological
behavioral
homeostasis.
Under
challenges,
stress-induced
dysbiosis
increases
gut
permeability
causes
serial
reactions:
releasing
neurotoxic
compounds,
leading
neuroinflammation
neuronal
injury,
eventually
aggressive,
violent,
impulsive
behavior
in
humans
animals
via
complex
bidirectional
communication
microbiota–gut–brain
(MGB)
axis.
The
dysregulation
MGB
axis
also
been
recognized
one
reasons
for
prevalence
injurious
behaviors
(feather
pecking,
aggression,
cannibalistic
pecking)
chickens.
However,
existing
knowledge
preventing
treating
these
both
chickens
is
not
well
understood.
In
previous
studies,
we
developed
non-mammal
model
abnormal
investigation
by
rationalizing
microbiota
Based
our
earlier
success,
perspective
article
outlines
possibility
reducing
through
modifying
cecal
transplantation,
potential
providing
biotherapeutic
rationale
among
individuals
restoring
diversity
function.
Язык: Английский
The moderating effect of frailty on the network of depression, anxiety, and loneliness in community-dwelling older adults
Journal of Affective Disorders,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Placebo treatment entails resource-dependent downregulation of negative inputs
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Март 17, 2025
Abstract
Clinical
trials
with
antidepressants
reveal
significant
improvements
in
placebo
groups,
effects
of
up
to
80%
compared
real
treatment.
While
it
has
been
suggested
that
treatment
expectations
rely
on
cognitive
control,
direct
evidence
for
affective
is
sparse.
Here,
we
investigated
how
resources
at
both
the
behavioral
and
neural
levels
influence
positive
emotional
processing.
Forty-nine
healthy
volunteers
participated
a
cross-over
fMRI
study
where
were
induced
through
an
alleged
oxytocin
nasal
spray
verbal
instruction.
Participants
completed
spatial
cueing
task
manipulated
attention
face
distractors
while
being
scanned
characterized
regarding
their
general
control
ability.
Placebo
improved
mood
reduced
distractibility
from
fearful
happy
faces,
particularly
when
more
attentional
available
processing
distractors.
This
aligned
changes
activation
functional
coupling
within
prefrontal-limbic
networks,
suggesting
induce
top-down
regulation
aversive
inputs.
Additionally,
neurobehavioral
correlated
individual
Our
findings
highlight
critical
role
verbally
instructed
effects.
may
be
relevant
patients
major
depressive
disorder,
who
often
demonstrate
enhanced
negativity
but
have
limited
capacity.
Язык: Английский
Midlife “crisis” or midlife awakening? Leisure as obstacle or opportunity
World Leisure Journal,
Год журнала:
2024,
Номер
unknown, С. 1 - 10
Опубликована: Окт. 11, 2024
The
"midlife
crisis"
is
a
popular
phrase
used
to
describe
the
condition
of
being
stuck
during
middle-age
years,
alongside
realization
that
one's
life
approximately
half
over.
It
called
crisis
because
how
it
often
socially
portrayed
and
personally
perceived:
something
must
be
done
ensure
one
makes
most
their
remaining
time.
In
following
sections,
we
assert
there
dearth
research
on
role
meaningful
leisure
pursuits
in
middle
adulthood
little
attempt
has
been
made
at
theoretical
development
transitions
midlife
as
relates
leisure.
We
also
posit
since
longest
stages,
would
valuable
develop
important
insights
into
successful
aging
for
"back
nine"Footnote1
exploring
these
issues
requires
us
understand
"psychological
clock"
resides
within
all.
Язык: Английский
Placebo treatment entails resource-dependent downregulation of negative inputs
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Сен. 5, 2023
Abstract
Background
Clinical
trials
of
antidepressants
show
improvements
in
placebo
groups
up
to
80%
compared
the
real
treatment
arm.
The
mechanism
underlying
this
clinically
important
effect
has
been
linked
expectation
induced
goal-directed
control.
Here,
we
investigated
how
cognitive
resources
influence
effects
positive
expectations
on
emotional
processing.
Methods
Forty-nine
healthy
volunteers
participated
a
cross-over
fMRI
study,
which
expectancy
changes
was
by
an
alleged
oxytocin
nasal
spray
combined
with
verbal
instruction.
Participants
performed
spatial
cueing
paradigm
that
manipulated
attention
face
distractors
scanner
and
were
characterized
regarding
their
general
ability
control
attention.
Results
Behavioral
findings
showed
improve
mood
reduce
distractibility
fearful
over
happy
faces,
specifically
when
more
attentional
available
process
faces.
This
aligned
neural
activation
functional
coupling
lateral
prefrontal-limbic
networks
indicating
top-down
regulation
aversive
inputs.
In
addition,
behavioral
prefrontal-parietal
engagement
directly
correlated
trait
Conclusions
Our
data
instruction
alone
can
recruit
selection.
Changes
processing
critically
depended
context
individual
(i.e.,
contextual
resources).
These
may
be
particularly
relevant
patients
major
depressive
disorder,
who
often
demonstrate
negativity
bias
whom
instructions
limited
due
reduced
capacity.
Язык: Английский