A long noncoding RNA at the cortex locus controls adaptive coloration in butterflies

Proceedings of the National Academy of Sciences, Год журнала: 2024, Номер 121(36)

Опубликована: Авг. 30, 2024

Evolutionary variation in the wing pigmentation of butterflies and moths offers striking examples adaptation by crypsis mimicry. The

Язык: Английский

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The ivory lncRNA regulates seasonal color patterns in buckeye butterflies

Proceedings of the National Academy of Sciences, Год журнала: 2024, Номер 121(41)

Опубликована: Окт. 1, 2024

Long noncoding RNAs (lncRNAs) are transcribed elements increasingly recognized for their roles in regulating gene expression. Thus far, however, we have little understanding of how lncRNAs contribute to evolution and adaptation. Here, show that a conserved lncRNA, ivory , is an important color patterning the buckeye butterfly Junonia coenia . overlaps with cortex locus linked multiple cases crypsis mimicry Lepidoptera. Along companion paper by Livraghi et al., argue not pattern interest at this locus. In J. cluster cis -regulatory (CREs) first intron genetically associated natural variation seasonal plasticity, targeted deletions these CREs phenocopy phenotypes. Deletions different produce other distinct phenotypes as well, including loss melanic eyespot rings, positive negative changes overall wing pigmentation. We transcription factors Spineless, Bric-a-brac, Ftz-f1 bind promoter during development, suggesting they directly regulate This case study demonstrates -regulation single RNA can exert diverse nuanced effects on development patterns, modulating seasonally plastic patterns.

Язык: Английский

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Mutation in Resilin reveals attachment impairment in Bombyx mori

Insect Science, Год журнала: 2025, Номер unknown

Опубликована: Март 6, 2025

Insects can effortlessly walk on various substrate surfaces using attachment pads their feet, even upside down smooth surfaces. These undergo frequent deformation throughout the lifecycle of insects to achieve stable adhesion. Interest in insect adhesion spans 100s years; studies have indicated special mechanical properties and intricate structural design pads. However, genetic basis function remains unclear. Resilin, an elastic protein widely distributed exoskeletons, plays a crucial role many physiological activities. Here, we identified resilin-like Lepidopteran Bombyx mori generated mutants for this gene. The resulting adults exhibited "slipping" phenotype reduced ability. Further behavioral investigations, microscopic observations performance tests, confirmed that mutation stiffened pads, reducing flexibility effective contact area, which ultimately led decreased adhesive ability adults. Molecular-level analyses revealed differential expression melanin metabolism-related genes, potentially explaining hardening abnormal pigmentation Our results provide phenotypic evidence demonstrating significant resilin attachment.

Язык: Английский

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Silkworm mutagenesis using a ribonucleoprotein-based CRISPR/Cas12a system

Insect Biochemistry and Molecular Biology, Год журнала: 2025, Номер unknown, С. 104329 - 104329

Опубликована: Май 1, 2025

Язык: Английский

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Nature's loom: How to design a spinning tool using chitin-protein based composite material

International Journal of Biological Macromolecules, Год журнала: 2024, Номер unknown, С. 135980 - 135980

Опубликована: Сен. 1, 2024

Язык: Английский

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