Neuronal identity control at the resolution of a single transcription factor isoform DOI Creative Commons
Natalie Smolin, Mark Dombrovski, Bryce W. Hina

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Июнь 14, 2024

The brain exhibits remarkable neuronal diversity which is critical for its functional integrity. From the sheer number of cell types emerging from extensive transcriptional, morphological, and connectome datasets, question arises how capable generating so many unique identities. 'Terminal selectors' are transcription factors hypothesized to determine final identity characteristics in post-mitotic cells. Which function as terminal selectors level control they exert over different not well defined. Here, we establish a novel role factor

Язык: Английский

Neuronal identity control at the resolution of a single transcription factor isoform DOI Creative Commons
Natalie Smolin, Mark Dombrovski, Bryce W. Hina

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Июнь 14, 2024

The brain exhibits remarkable neuronal diversity which is critical for its functional integrity. From the sheer number of cell types emerging from extensive transcriptional, morphological, and connectome datasets, question arises how capable generating so many unique identities. 'Terminal selectors' are transcription factors hypothesized to determine final identity characteristics in post-mitotic cells. Which function as terminal selectors level control they exert over different not well defined. Here, we establish a novel role factor

Язык: Английский

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