Abstract
Acute
environmental
stressors
such
as
short-term
exposure
to
pollutants
can
have
lasting
effects
on
organisms,
potentially
impacting
future
generations.
Parental
toxicants
result
in
changes
the
epigenome
(e.g.,
DNA
methylation)
that
are
passed
down
subsequent,
unexposed
However,
it
is
difficult
gauge
cumulative
population-scale
impacts
of
epigenetic
from
laboratory
experiments
alone.
Here,
we
developed
a
size-
and
age-structured
delay-coordinate
population
model
evaluate
long-term
consequences
modifications
sustainability.
The
emulated
growth,
mortality,
fecundity
F0,
F1,
F2
generations
observed
which
larval
Menidia
beryllina
were
exposed
environmentally
relevant
concentrations
bifenthrin
(Bif),
ethinylestradiol
(EE2),
levonorgestrel
(LV),
or
trenbolone
(TB)
parent
generation
(F0)
reared
clean
water
up
generation.
Our
analysis
suggests
dramatic
population-level
repeated,
chronic
exposures
early-life
stage
fish
not
captured
by
models
accounting
for
those
effects.
Simulated
led
substantial
declines
abundance
(LV
Bif)
near-extinction
(EE2
TB)
with
exact
trajectory
timeline
decline
dependent
combination
produced
each
compound.
Even
acute
one-time
compound
recovery
over
multiple
years
due
lagged
These
results
demonstrate
potential
commonly
used
compounds
impact
dynamics
sustainability
an
ecologically
species
organism.
