Abstract
Background
Recent
advances
in
large
language
models
(LLM)
have
enabled
human-like
qualities
of
natural
competency.
Applied
to
oncology,
LLMs
been
proposed
serve
as
an
information
resource
and
interpret
vast
amounts
data
a
clinical
decision-support
tool
improve
outcomes.
Objective
This
review
aims
describe
the
current
status
medical
accuracy
oncology-related
LLM
applications
research
trends
for
further
areas
investigation.
Methods
A
scoping
literature
search
was
conducted
on
Ovid
Medline
peer-reviewed
studies
published
since
2000.
We
included
primary
that
evaluated
model
applied
oncology
settings.
Study
characteristics
outcomes
were
extracted
landscape
LLMs.
Results
Sixty
based
inclusion
exclusion
criteria.
The
majority
health
question-answer
style
examinations
(48%),
followed
by
diagnosis
(20%)
management
(17%).
number
utility
fine-tuning
prompt-engineering
increased
over
time
from
2022
2024.
Studies
reported
advantages
accurate
resource,
reduction
clinician
workload,
improved
accessibility
readability
information,
while
noting
disadvantages
such
poor
reliability,
hallucinations,
need
oversight.
Discussion
There
exists
significant
interest
application
with
particular
focus
decision
support
tool.
However,
is
needed
validate
these
tools
external
hold-out
datasets
generalizability
across
diverse
scenarios,
underscoring
supervision
tools.
Applied Ergonomics,
Год журнала:
2025,
Номер
128, С. 104515 - 104515
Опубликована: Апрель 17, 2025
The
emergence
of
large
language
models
offers
new
opportunities
to
deliver
effective
healthcare
information
through
web-based
chatbots.
Health
is
often
complex
and
technical,
making
it
crucial
design
human-AI
interactions
that
effectively
meet
user
needs.
Employing
a
2x2
between
subjects
design,
we
controlled
for
two
independent
variables:
communication
style
(conversational
vs.
informative)
(technical
non-technical).
We
used
hierarchical
Bayesian
regression
assess
the
impact
varying
presentation
styles
on
effectiveness,
trustworthiness,
usability.
findings
revealed
perceptions
low
usability
significantly
decreased
effectiveness
chatbot.
Additionally,
participants
exposed
conversational
chatbot
had
increased
likelihoods
perceive
with
higher
but
were
also
more
likely
be
less
trusting
These
results
indicate
can
experience
insights
future
research
chatbots
other
AI
systems.
Abstract
Background
Recent
advances
in
large
language
models
(LLM)
have
enabled
human-like
qualities
of
natural
competency.
Applied
to
oncology,
LLMs
been
proposed
serve
as
an
information
resource
and
interpret
vast
amounts
data
a
clinical
decision-support
tool
improve
outcomes.
Objective
This
review
aims
describe
the
current
status
medical
accuracy
oncology-related
LLM
applications
research
trends
for
further
areas
investigation.
Methods
A
scoping
literature
search
was
conducted
on
Ovid
Medline
peer-reviewed
studies
published
since
2000.
We
included
primary
that
evaluated
model
applied
oncology
settings.
Study
characteristics
outcomes
were
extracted
landscape
LLMs.
Results
Sixty
based
inclusion
exclusion
criteria.
The
majority
health
question-answer
style
examinations
(48%),
followed
by
diagnosis
(20%)
management
(17%).
number
utility
fine-tuning
prompt-engineering
increased
over
time
from
2022
2024.
Studies
reported
advantages
accurate
resource,
reduction
clinician
workload,
improved
accessibility
readability
information,
while
noting
disadvantages
such
poor
reliability,
hallucinations,
need
oversight.
Discussion
There
exists
significant
interest
application
with
particular
focus
decision
support
tool.
However,
is
needed
validate
these
tools
external
hold-out
datasets
generalizability
across
diverse
scenarios,
underscoring
supervision
tools.