Breaking the cycle: Psychological and social dimensions of pediatric functional gastrointestinal disorders DOI
Mohammed Al‐Beltagi, Nermin Kamal Saeed, Adel Salah Bediwy

и другие.

World Journal of Clinical Pediatrics, Год журнала: 2025, Номер 14(2)

Опубликована: Март 18, 2025

BACKGROUND Functional gastrointestinal disorders (FGIDs) in children present with chronic symptoms like abdominal pain, diarrhea, and constipation without identifiable structural abnormalities. These are closely linked to gut-brain axis dysfunction, altered gut microbiota, psychosocial stress, leading psychiatric comorbidities such as anxiety, depression, behavioral issues. Understanding this bidirectional relationship is crucial for developing effective, holistic management strategies that address physical mental health. AIM To examine the impacts of FGIDs children, focusing on anxiety depression their association other neurodevelopmental childhood, attention-deficit/hyperactivity disorder, emphasizing role axis, emotional dysregulation, stress. Key mechanisms explored include neurotransmitter microbiota imbalance, central sensitization, heightening stress reactivity, symptom perception. The review also evaluates family dynamics coping exacerbating FGID contributing conditions. METHODS A narrative was conducted using 328 studies sourced from PubMed, Scopus, Google Scholar, covering research published over past 20 years. Inclusion criteria focused examining diagnosis, mechanisms, comorbidities, factors pediatric populations. commonly affecting including functional constipation, irritable bowel syndrome, gastroesophageal reflux, cyclic vomiting were analyzed concerning psychological impacts. RESULTS highlights a strong connection between symptoms, mediated by dysregulated sensitization. physiological disruptions increase children’s vulnerability while - early-life trauma, maladaptive dynamics, ineffective intensify cycle distress. CONCLUSION Effective requires biopsychosocial approach integrating medical, psychological, dietary interventions. Parental education, early intervention, multidisciplinary care coordination critical mitigating long-term improving both health outcomes FGIDs.

Язык: Английский

Factors influencing the quality of life of postpartum women: a systematic review DOI
Mostofa Jamal,

Firoozeh Rakhshani Moghadam,

Bakhtyar Hassan Muhammadamin Malkari

и другие.

Current Psychology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 28, 2025

Язык: Английский

Процитировано

1

Chatbot to Support the Mental Health Needs of Pregnant and Postpartum Women (Moment for Parents): Design and Pilot Study DOI Creative Commons
Kelsey McAlister, Lara Baez, Jennifer Huberty

и другие.

JMIR Formative Research, Год журнала: 2025, Номер 9, С. e72469 - e72469

Опубликована: Апрель 8, 2025

Abstract Background Maternal mental health disorders are prevalent, yet many individuals do not receive adequate support due to stigma, financial constraints, and limited access care. Digital interventions, particularly chatbots, have the potential provide scalable, low-cost support, but few tailored specifically needs of perinatal individuals. Objective This study aimed (1) design develop Moment for Parents, a chatbot education (2) assess usability through engagement, usage patterns, user experience. Methods used human-centered rules-based pregnant postpartum In phase 1, ethnographic interviews (n=43) explored inform development. 2, total 108 were recruited participate in pilot test had unrestricted chatbot. Engagement was tracked over 8 months patterns re-engagement rates. After 1 month, participants completed usability, relevance, satisfaction survey, providing key insights refining Results Key themes that came from included need trusted resources, emotional better guidance. These informed content, including mood-based exercises coping strategies. Re-engagement high (69/108, 63.9%), meaning users who stopped interacting at least week returned once. A large proportion (28/69, 40.6%) re-engaged 3 or more times. Overall, 28/30 (93.3%) found relevant them, though some noted repetitive content response options. Conclusions The Parents successfully engaged with higher-than-typical retention patterns. findings underscore importance flexible, digital needs. Future research should examine how intermittent use influences outcomes refine delivery enhance long-term engagement effectiveness.

Язык: Английский

Процитировано

1

A Comprehensive Review of Motherhood and Mental Health: Postpartum Mood Disorders in Focus DOI Open Access

Anushree Modak,

Vaishnavi Ronghe,

Kavita Gomase

и другие.

Cureus, Год журнала: 2023, Номер unknown

Опубликована: Сен. 29, 2023

The journey of motherhood encompasses a profound array emotions, experiences, and challenges that extend beyond the surface joy elation. This review delves into crucial yet often underexplored realm postpartum mood disorders, aiming to illuminate their significance foster understanding. Postpartum including depression, anxiety psychosis, impact mental well-being mothers during pivotal phase lives. Through comprehensive exploration, this elucidates various dimensions these from definitions classifications prevalence on both families. Identifying diagnosing disorders is discussed in detail, shedding light emotional, cognitive, physical symptoms warrant attention. Screening assessment tools are highlighted as essential instruments for early detection, while diagnosis, overlap with typical experiences influence stigma, explored. further treatment intervention, underscoring importance psychotherapy, pharmacological interventions, individualised plans. roles healthcare providers health professionals offering support guidance emphasised, emphasising collaborative approach. Cultural societal influences shaping perceptions health. explores how can create barriers seeking help highlights destigmatising disorders. It underscores urgency raising awareness fostering supportive environment empowers seek assistance without fear judgment. Looking toward future, points potential research directions, such advances understanding hormonal exploring long-term effects maternal overarching call action resonates - increased awareness, support, dismantling stigma imperative. A hopeful vision presented: future where all receive appropriate care, no mother stands alone her journey, compassion thrive.

Язык: Английский

Процитировано

21

Blood metabolomic and postpartum depression: a mendelian randomization study DOI Creative Commons
Keng Ling,

Minping Hong,

Liqin Jin

и другие.

BMC Pregnancy and Childbirth, Год журнала: 2024, Номер 24(1)

Опубликована: Июнь 14, 2024

Abstract Background Postpartum depression is a complex mental health condition that often occurs after childbirth and characterized by persistent sadness, anxiety, fatigue. Recent research suggests metabolic component to the disorder. This study aims investigate causal relationship between blood metabolites postpartum using mendelian randomization (MR). Methods used bi-directional MR framework 1,400 biomarkers depression. We two specific genome-wide association studies datasets: one with single nucleotide polymorphisms data from mothers diagnosed another metabolite data, both of which focused on people European ancestry. Genetic variants were chosen as instrumental variables datasets strict criteria improve robustness analysis. The combination these enabled thorough examination genetic influences profiles associated Statistical analyses conducted techniques such inverse variance weighting, weighted median, model-based estimation, rigorous inference observed associations. was defined endpoint definitions approved FinnGen study’s clinical expert groups, included leading experts in their respective medical fields. Results analysis identified seven could be linked Out these, found protective, while six an increased risk developing condition. results consistent across multiple methods, indicating significant correlation. Conclusions emphasizes potential metabolomics for understanding discovery sheds new insights its pathophysiology opens up possibilities future into targeted treatment strategies.

Язык: Английский

Процитировано

5

In the Shadows of Motherhood: A Comprehensive Review of Postpartum Depression Screening and Intervention Practices DOI Open Access
Aishwarya Gupta,

Sandhya Pajai,

Anusha Gupta

и другие.

Cureus, Год журнала: 2024, Номер unknown

Опубликована: Фев. 15, 2024

This comprehensive review delves into the multifaceted landscape of postpartum depression (PPD), exploring its prevalence, impact on maternal and infant well-being, efficacy existing screening intervention practices. PPD emerges as a critical concern, with implications extending beyond individual mental health to encompass dynamics mother-infant relationships societal well-being. The analysis underscores complexity addressing PPD, emphasizing challenges associated tools importance evidence-based interventions. A call action resonates throughout, urging healthcare providers, policymakers, stakeholders prioritize support for new mothers through enhanced protocols improved accessibility Furthermore, highlights need destigmatization awareness campaigns foster supportive environment. Future research directions are outlined, refinement tools, developing innovative interventions, cultural socioeconomic influences outcomes. envisions collaborative effort dispel shadows striving future where receive support, ensuring optimal overall

Язык: Английский

Процитировано

4

Cradling disparities: A descriptive qualitative study of maternal experiences of mothers from low‐socioeconomic status in the first month postpartum DOI
Shefaly Shorey,

Jamie Qiao Xin Ng,

V. Liu

и другие.

Journal of Advanced Nursing, Год журнала: 2024, Номер unknown

Опубликована: Май 10, 2024

Abstract Aim To explore the experiences, expectations and needs of mothers from low‐socioeconomic status at 1 month postpartum. Design Descriptive qualitative. Methods Mothers irrespective their parity were invited to participate in one‐to‐one interviews Semi‐structured conducted until data saturation. Interviews audio recorded, transcribed verbatim analysed thematically. Written informed consent was obtained. Results Twenty participated six themes identified: (1) No choice but find meaning; (2) Father as a major pillar support; (3) ‘Kampung’ Spirit; (4) Trials Tribulations Transition Motherhood; (5) Shame, guilt internalized stigma (6) Reclaiming power. Conclusion This study reflected unique struggles with pregnancy, childbirth early postpartum wider health inequities within Singapore's maternal system. provide much‐needed support improved care, stakeholders government, healthcare providers social organizations should consider niche this community. Implications for Patient Care Nurses need reflect on own biases ensure consistent care delivery regardless socioeconomic status. When delivering patient education, patient‐centred sincere advice rooted personal experience can help establish rapport. Impact is first experiences Singapore context. Low‐socioeconomic experienced less autonomy over health, they received childcare options. As adjusted new roles, struggled cope. However, wary surrounding poverty not being ‘good mother’, preferred seek informal family, friends self‐help through learning media, compared formal, external help. Reporting Method COREQ checklist. or Public Contribution public contribution.

Язык: Английский

Процитировано

4

Bridging Neurobiological Insights and Clinical Biomarkers in Postpartum Depression: A Narrative Review DOI Open Access
Keyi Zhang,

Lingxuan He,

Z. B. Li

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(16), С. 8835 - 8835

Опубликована: Авг. 14, 2024

Postpartum depression (PPD) affects 174 million women worldwide and is characterized by profound sadness, anxiety, irritability, debilitating fatigue, which disrupt maternal caregiving the mother–infant relationship. Limited pharmacological interventions are currently available. Our understanding of neurobiological pathophysiology PPD remains incomplete, potentially hindering development novel treatment strategies. Recent hypotheses suggest that driven a complex interplay hormonal changes, neurotransmitter imbalances, inflammation, genetic factors, psychosocial stressors, hypothalamic–pituitary–adrenal (HPA) axis dysregulation. This narrative review examines recent clinical studies on within past 15 years, emphasizing advancements in neuroimaging findings blood biomarker detection. Additionally, we summarize laboratory work using animal models to mimic PPD, focusing hormone withdrawal, HPA dysfunction, perinatal stress theories. We also revisit results from several brain regions associated with negative emotions, such as amygdala, prefrontal cortex, hippocampus, striatum. These insights aim improve our PPD’s mechanisms, guiding future research for better early detection, prevention, personalized strategies affected their families.

Язык: Английский

Процитировано

4

Proactive approaches to preventing postpartum depression in non-depressive pregnant women: a comprehensive scoping review DOI Creative Commons
Nga Nguyen, Supa Pengpid

Frontiers in Global Women s Health, Год журнала: 2025, Номер 6

Опубликована: Апрель 9, 2025

Postpartum depression is a significant global health challenge that affects mothers, infants, and families. Although various preventive strategies show promise, comprehensive reviews evaluating interventions among pregnant women without clinical diagnosis of remain limited. This scoping review aims to identify synthesize the existing evidence on proactive postpartum prevention programs initiated during pregnancy. Following PRISMA guidelines for reviews, we systematically searched PubMed Scopus, supplemented by manual reference reviews. Our search strategy combined terms related depression, pregnancy, interventions. Studies were included if they evaluated conducted targeting assessed PPD outcomes using established diagnostic criteria or validated screening tools. Only English-language articles published between 2013 2023 considered. A total 49 studies met inclusion criteria. Interventions categorized into nine themes: psychoeducation (n = 18), home visits 6), cognitive behavioral therapy (CBT) mindfulness exercise 4), dietary supplements 3), interpersonal (IPT) consultation 1), inhalation aromatherapy 1). Psychoeducational mindfulness-based consistently reduce risk, particularly when delivered in structured, theory-driven formats incorporating family support. Digital CBT demonstrated limited effectiveness due lower engagement, while home-visit consultation-based effective integrated maternal healthcare despite scalability challenges. Exercise supplement yielded inconsistent outcomes, indicating factors such as adherence, duration, intensity are crucial determinants effectiveness. Various available prevent PPD, this maps different used their outcomes. Proactive, theory-based, multi-component interventions, psychoeducational programs, demonstrate promising potential. Future research should emphasize long-term optimizing digital engagement strategies, developing culturally tailored models enhance accessibility across diverse populations, including low-resource settings.

Язык: Английский

Процитировано

0

Heart Rate Variability Measurement Can Be a Point-of-Care Sensing Tool for Screening Postpartum Depression: Differentiation from Adjustment Disorder DOI Creative Commons
Toshikazu Shinba, H. Suzuki,

Michiko Urita

и другие.

Sensors, Год журнала: 2024, Номер 24(5), С. 1459 - 1459

Опубликована: Фев. 23, 2024

Postpartum depression (PPD) is a serious mental health issue among women after childbirth, and screening systems that incorporate questionnaires have been utilized to screen for PPD. These are sensitive but less specific, the additional use of objective measures could be helpful. The present study aimed verify usefulness measure autonomic function, heart rate variability (HRV), which has reported dysregulated in people with depression. Among 935 who had experienced childbirth completed Edinburgh Postnatal Depression Scale (EPDS), HRV was measured EPDS-positive (n = 45) 1 4 weeks using wearable device. measurement based on three-behavioral-state paradigm 5 min duration, consisting rest (Rest), task load (Task), rest-after-task (After) states, low-frequency power (LF), high-frequency (HF), their ratio (LF/HF) were calculated. included this study, 12 diagnosed PPD 33 adjustment disorder (AJD). Women showed lack adequate regulation response load, accompanying high LF/HF score Rest state. On other hand, AJD exhibited HF reduced during After A linear discriminant analysis indices (HR) revealed both differentiation patients from controls possible. sensitivity specificity vs. 75.0% 90.9%, respectively. Using paradigm, an characteristic profiles AJD, suggesting it may serve as point-of-care sensing tool systems.

Язык: Английский

Процитировано

3

Improving parental mental health in the perinatal period: A review and analysis of quality improvement initiatives DOI

Sofia Perazzo,

Margaret K. Hoge, Richard J. Shaw

и другие.

Seminars in Perinatology, Год журнала: 2024, Номер 48(3), С. 151906 - 151906

Опубликована: Апрель 1, 2024

Язык: Английский

Процитировано

3