Vaginal Dysbiosis in Infertility: A Comparative Analysis Between Women with Primary and Secondary Infertility DOI Creative Commons
Iliana Alejandra Cortés-Ortíz,

Gustavo Acosta‐Altamirano,

Rafael Nambo‐Venegas

и другие.

Microorganisms, Год журнала: 2025, Номер 13(1), С. 188 - 188

Опубликована: Янв. 17, 2025

Infertility, both primary and secondary, is strongly influenced by microbiological factors, with the vaginal microbiota playing a key role in reproductive health. The aim of this study was to characterize 136 Mexican women diagnosed infertility-primary (n = 58) secondary 78)-by evaluating presence pathogenic bacterial species their associations infertility conditions. Samples were obtained through cervical swabs, microorganism identification performed using qPCR techniques. Analysis revealed positive correlation between increased age likelihood infertility, as well negative infertility. Significant differences microbial composition also observed two groups. Lactobacillus crispatus gasseri dominant addition high prevalence Gardnerella vaginalis Fannyhessea vaginae. Additionally, correlations found human papillomavirus (HPV) sexually transmitted bacteria, vaginalis. Our findings suggest that may play decisive highlighting need for personalized therapeutic strategies based on profiles.

Язык: Английский

Vaginal Dysbiosis in Infertility: A Comparative Analysis Between Women with Primary and Secondary Infertility DOI Creative Commons
Iliana Alejandra Cortés-Ortíz,

Gustavo Acosta‐Altamirano,

Rafael Nambo‐Venegas

и другие.

Microorganisms, Год журнала: 2025, Номер 13(1), С. 188 - 188

Опубликована: Янв. 17, 2025

Infertility, both primary and secondary, is strongly influenced by microbiological factors, with the vaginal microbiota playing a key role in reproductive health. The aim of this study was to characterize 136 Mexican women diagnosed infertility-primary (n = 58) secondary 78)-by evaluating presence pathogenic bacterial species their associations infertility conditions. Samples were obtained through cervical swabs, microorganism identification performed using qPCR techniques. Analysis revealed positive correlation between increased age likelihood infertility, as well negative infertility. Significant differences microbial composition also observed two groups. Lactobacillus crispatus gasseri dominant addition high prevalence Gardnerella vaginalis Fannyhessea vaginae. Additionally, correlations found human papillomavirus (HPV) sexually transmitted bacteria, vaginalis. Our findings suggest that may play decisive highlighting need for personalized therapeutic strategies based on profiles.

Язык: Английский

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