Journal of Ophthalmology,
Год журнала:
2024,
Номер
2024(1)
Опубликована: Янв. 1, 2024
To
investigate
the
efficacy
and
safety
of
orthokeratology
(ortho-k)
repeated
low-level
red-light
(RLRL)
therapy
in
treating
poor
responders
ortho-k
myopic
children.
British Journal of Ophthalmology,
Год журнала:
2024,
Номер
108(9), С. 1299 - 1305
Опубликована: Апрель 17, 2024
Background/aims
To
compare
the
effects
of
repeated
low-level
red
light
(RLRL)
treatment
on
axial
length
growth
and
refractive
error
changes
in
myopic
premyopic
children.
Methods
Subjects
were
assigned
randomly
to
four
subgroups:
myopia-RLRL
group
(M-RL),
myopia-control
(M-C),
premyopia-RLRL
(PM-RL)
premyopia-control
(PM-C).
RLRL
completed
a
12-month
composed
3
min
session
twice
daily,
with
an
interval
at
least
4
hours,
for
7
days
per
week.
Visits
scheduled
before
1-month,
3-month,
6-month,
9-month
follow-up
after
treatment.
Repeated-measures
analysis
variance
was
used
spherical
equivalent
errors
(SE)
(AL)
between
groups
across
period.
Results
After
12
months
treatment,
myopia
group,
SE
AL
−0.078±0.375
D
0.033±0.123
mm
M-RL
−0.861±0.556
0.415±0.171
M-C;
premyopia
progression
−0.181±0.417
0.145±0.175
PM-RL
−0.521±0.436
0.292±0.128
PM-C.
indicated
lower
incidence
than
PM-C
(2.5%
vs
19.4%).
Additionally,
percentage
shortening
higher
that
follow-up.
Conclusion
effectively
delayed
children
reduced
Moreover,
exhibited
stronger
impact
compared
individuals.
Nature,
Год журнала:
2024,
Номер
629(8014), С. 989 - 991
Опубликована: Май 29, 2024
Time
spent
outdoors
is
the
best
defence
against
rising
rates
of
short-sightedness,
but
scientists
are
searching
for
other
ways
to
reverse
troubling
trend.
American Journal of Ophthalmology,
Год журнала:
2024,
Номер
269, С. 60 - 68
Опубликована: Авг. 27, 2024
PurposeSpectacle
lenses
with
highly
aspherical
lenslets
(HAL)
have
been
shown
to
effectively
retard
myopia
progression
in
myopic
children.
This
study
aimed
investigate
the
impact
of
spectacle
HAL
on
refractive
and
axial
length
(AL)
changes
Chinese
children
low
amount
hyperopia.DesignRandomized
controlled
trial.MethodsA
total
108
aged
6.0
9.9
years
spherical
equivalent
error
(SERE)
from
0.00
+2.00
D
were
randomly
allocated
into
two
groups:
group
single
vision
lens
(SVL)
group.
Cycloplegic
refraction,
AL,
uncorrected
visual
acuity
measured
at
baseline,
6
12
months
after
dispensing.
The
duration
wear
was
monitored
using
a
wearable
device
attached
frame
by
questionnaire
logs
provided
participants
each
follow-up
visit.ResultsThe
1-year
SERE
change
–0.19
(–0.32,
0.03)
−0.23
(–0.36,
0.05)
SVL
groups
(P
=
.883).
AL
elongation
0.24
(0.18,
0.34)
mm
0.19
(0.12,
0.27)
.057).
In
group,
significantly
correlated
wearing
time
<
.001
P
.024,
respectively).
Participants
who
wore
their
for
more
than
30
hours
per
week
had
slower
(0.11
[0.05,
0.17]
mm)
compared
counterparts
(0.27
[0.21,
0.33]
.001).ConclusionsSpectacle
reduced
hyperopic
over
week.
A
dose-response
relationship
evident
longer
associated
less
change.
American Journal of Ophthalmology,
Год журнала:
2024,
Номер
270, С. 203 - 215
Опубликована: Окт. 16, 2024
To
evaluate
the
effectiveness
and
safety
of
repeated
low-level
red-light
(RLRL)
in
delaying
progression
high
myopes
with
-6.00
diopters
(D)
or
worse.
Multicenter,
randomized,
parallel-group,
single-blind
clinical
trial.
A
total
202
myopic
children
aged
7
to
12
years
cycloplegia
spherical
equivalent
(SE)
refraction
≤-6.00
D,
astigmatism
less
than
2.50
anisometropia
1.50
D
were
enrolled
from
March
2022
December
2022.
Follow-up
was
completed
2023.
Eligible
participants
randomly
allocated
intervention
(RLRL
+
single
vision
spectacle)
control
group
(single
spectacle).
The
RLRL
treatment
administered
every
day
for
3
minutes,
twice
a
day,
an
interval
at
least
4
hours.
primary
outcome
change
axial
length
(AL)
months
compared
baseline.
Secondary
outcomes
included
changes
SE,
choroidal
thickness
(ChT),
retinal
(RT)
different
circle
sectors.
Outcomes
analyzed
by
means
intention-to-treat
per-protocol
methods.
After
treatment,
AL
SE
-0.11
±
0.25
mm
0.18
0.63
0.32
0.09
-0.80
0.42
group,
respectively.
Axial
shortening
>0.05
59%
0%
months.
ChT
RT
center
analyzed.
In
thickened
all
sectors
increased
parafoveal
perifoveal
circles.
only
significantly
thinner
multivariate
linear
regression
model
revealed
significant
correlations
between
central
foveal
1
month
No
fundus
structure
changes,
afterimage
exceeding
6
best-corrected
visual
acuity
decrease
reported.
could
effectively
shorten
inhibit
myopia
patients
is
sustained
over
treatment.
These
observed
appeared
be
associated
increases
RT.
Seminars in Ophthalmology,
Год журнала:
2025,
Номер
unknown, С. 1 - 6
Опубликована: Янв. 18, 2025
This
meta-analysis
aims
to
systematically
analyze
the
efficacy
of
low-level
red
light
(LRL)
therapy
for
myopia
control
and
prevention
in
children.
All
data
were
searched
from
PubMed,
EMBASE,
Cochrane
Library.
The
Handbook
was
used
evaluate
quality
included
studies.
Additionally,
this
performed
by
using
Revman
5.4
software.
Inclusion
criteria
randomized
controlled
trials
(RCTs),
patient
populations
younger
than
18
years.
Eight
RCTs
study.
Compared
with
group,
LRL
treatment
could
reduce
progression
spherical
equivalent
refractive
(SER)
children
(MD,
0.49;
95%
CI,
0.27
0.71;
p
<
.00001).
Also,
less
change
axial
length
(AL)
increase
subfoveal
choroid
thickness
(SFCT)
shown
group
both
premyopia
-0.24,
28.16;
-0.32
-0.17,
18.78
37.55;
.00001,
respectively).
Our
shows
that
delay
refraction
It
also
SFCT
thinning
premoypia
European Journal of Ophthalmology,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 21, 2025
Introduction
Myopia
is
a
refractive
error
where
distant
objects
are
not
clearly
seen
and
appear
blurred.
Goal
of
this
study
was
to
evaluate
long-term
effectiveness
Repeated
Low-Level
Red
Light
(RLRL)
therapy
for
children
with
myopia,
which
primarily
focused
on
Axial
length
(AL)
Spherical
Equivalent
Refraction
(SER)
as
primary
endpoints.
Methods
The
research
compared
outcomes
between
RLRL
treatment
Single
Vision
Spectacles
(SVS)
childhood
myopia
management.
We
performed
systematic
literature
search
in
the
PubMed,
Embase
Cochrane
databases
using
“Myopia”
“
“.
Mean
differences
(MD)
were
estimated
effects
therapies
measured.
Publication
bias
heterogeneity
analysis
carried
out
by
Inverted
Precision
Effect
Test-Precision
Estimate
Standard
Error
(PET-PEESE)
(and
subsequent
Search
Sequential
Analysis)
Tau
test.
Bayesian
meta-analysis
Jaffrey
Amazing
Statistical
Package
(JASP).
Results
This
comprised
1,714
participants:
824
890
SVS
group.
Pooled
effect
size
AL
reduction
0.953
±
0.294,
(95%
credible
interval
(CI)
0.775
0.980).
SER
1.521
0.662
CI
0.102
2.736).
PET-PEESE
revealed
no
significant
publication
(
p-value
0.407).
Random
models
employed
presence
(3.9
5.7
AL;
SER),
alongside
degree
variation
(0.828
&
1.665)
(τ),
estimates
between-study
variance.
Conclusion
Long-term
observations
indicate
that
significantly
influences
management,
leading
considerable
reductions
both
SER.
Additional
essential
investigate
potential
rebound
effects.