Community Threat, Positive Parenting, and Accelerated Epigenetic Aging: Longitudinal Links from Childhood to Adolescence DOI Creative Commons

Georgette Metrailer,

Karina Tavares,

Mikayla Ver Pault

и другие.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Дек. 26, 2024

Early Life Adversity (ELA) has been linked to accelerated epigenetic aging. While positive parenting is hypothesized buffer the detrimental effects of ELA on child development, its role in mitigating age acceleration remains unclear. Data from 2,039 children (49.7% female) Future Families and Child Wellbeing Study (FFCWS) were included current study (46.7% Black, 26.5% Hispanic, 19% White non-Hispanic). Home community threat observed measured ages 3 9. Salivary was at 9 15. Positive reduces pace aging low, but not high, community-threat environments. Interventions across home environments may be necessary prevent ELA's biological embedding.

Язык: Английский

Profiling Changes in the Needs of Caregivers With Child Welfare Involvement: What Do They Tell Us About Risk for Maltreatment? DOI
Olivia D. Chang, Yujeong Chang, Susan Yoon

и другие.

Child Maltreatment, Год журнала: 2025, Номер unknown

Опубликована: Апрель 8, 2025

The present study examined profiles of service needs among caregivers with child welfare involvement. Participants were 589 children 12–36 months old at baseline from the second National Survey Child and Adolescent Well-Being. Latent class analysis was used to profile unique characteristics changes in caregivers’ across an 18-month period. Four classes caregiver identified differential risks for maltreatment. Compared “No Needs” (25%), “Chronic Multi-Type” (25%) “Parenting Only” (26%) both significantly more likely engage psychological aggression, physical abuse, neglect. Caregivers “Changing (24%) aggression Involvement services represents a critical opportunity offer support families, especially those multiple chronic needs, needing parenting skills, that are unstable over time.

Язык: Английский

Процитировано

0

Advancing Health Disparities Science Through Social Epigenomics Research DOI Creative Commons
Arielle S. Gillman, Eliseo J. Pérez‐Stable, Rina Das

и другие.

JAMA Network Open, Год журнала: 2024, Номер 7(7), С. e2428992 - e2428992

Опубликована: Июль 29, 2024

Importance Although scientific and technological discoveries have improved the health of US population overall, racial ethnic minority (American Indian Alaska Native, Asian, Black or African American, Hispanic Latino, Native Hawaiian Pacific Islander persons) socioeconomically disadvantaged populations continue to experience a disproportionate burden disease other adverse conditions. To better understand address drivers disparities inform development effective interventions, integrative mechanistic studies examining dynamic interplay multiple factors across life course even between generations are needed. The emerging field social epigenomics, which seeks link stressors protective status through examination epigenomic modifications various biological pathways, is one promising area research contributing this need. Observations This thematic issue JAMA Network Open highlights new findings from grantees National Institutes Health (NIH) Social Epigenomics Program. These findings, taken together, examine associations variety social, behavioral, structural throughout with changes among experiencing disparities. early-life exposures, inequities, behavioral interventions epigenetic changes, in some studies, later outcomes. While there still more work be done fully characterize pathways linking exposures outcomes, body presented special represents solid progress toward goal. Conclusions Relevance highlighted demonstrate important complex integration determinants outcomes improve understanding mechanisms underlying underserved populations. Continued remains integrating different disciplines transform research.

Язык: Английский

Процитировано

3

Childcare subsidy receipt and reduced emotional neglect: Examining parents' enhanced self-efficacy as a mediator DOI
Olivia D. Chang, Kathryn Maguire‐Jack, Katherine E. Marçal

и другие.

Child Abuse & Neglect, Год журнала: 2024, Номер 159, С. 107184 - 107184

Опубликована: Дек. 2, 2024

Язык: Английский

Процитировано

1

Childhood Adversity and Adolescent Epigenetic Age Acceleration: The Role of Adolescent Sleep Health DOI Creative Commons
Karissa DiMarzio, Darlynn M. Rojo‐Wissar, Evelyn M. Hernandez

и другие.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Сен. 3, 2024

We investigated how a dimension of early life adversity (ELA) capturing threat in the home relates to later epigenetic age acceleration adolescence through sleep (duration, efficiency, and timing), empirically test theoretical models suggesting importance as key mechanism linking ELA with poor health outcomes, expand limited literature on aging among youth.

Язык: Английский

Процитировано

0

Community Threat, Positive Parenting, and Accelerated Epigenetic Aging: Longitudinal Links from Childhood to Adolescence DOI Creative Commons

Georgette Metrailer,

Karina Tavares,

Mikayla Ver Pault

и другие.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Дек. 26, 2024

Early Life Adversity (ELA) has been linked to accelerated epigenetic aging. While positive parenting is hypothesized buffer the detrimental effects of ELA on child development, its role in mitigating age acceleration remains unclear. Data from 2,039 children (49.7% female) Future Families and Child Wellbeing Study (FFCWS) were included current study (46.7% Black, 26.5% Hispanic, 19% White non-Hispanic). Home community threat observed measured ages 3 9. Salivary was at 9 15. Positive reduces pace aging low, but not high, community-threat environments. Interventions across home environments may be necessary prevent ELA's biological embedding.

Язык: Английский

Процитировано

0