Frontiers in Bioengineering and Biotechnology,
Год журнала:
2024,
Номер
12
Опубликована: Сен. 13, 2024
Piezoelectric
materials,
as
a
class
of
materials
capable
generating
electrical
charges
under
mechanical
vibration,
have
special
piezoelectric
effects
and
been
widely
applied
in
various
disease
treatment
fields.
People
generate
vibrations
the
oral
cavity
during
daily
activities
such
brushing
teeth,
using
electric
toothbrushes,
chewing,
speaking.
These
natural
(or
external
ultrasound)
provide
ideal
conditions
for
activating
leading
to
their
high
potential
applications
protecting
health
treating
diseases.
Based
on
this,
this
review
reports
research
progress
trends
protection
diseases
past
5
years,
discusses
its
mechanism,
challenges
shortcomings,
aiming
theoretical
basis
new
ideas
future
application
field
cavity.
Finally,
brief
outlook
is
provided,
suggesting
that
may
enable
them
quickly
move
towards
real
clinical
applications.
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 2, 2025
Medical
catheters
are
susceptible
to
biological
contamination
and
pathogen
invasion,
leading
infection
inflammatory
complications.
The
development
of
antimicrobial
coatings
for
medical
devices
has
emerged
as
a
promising
strategy.
However,
limited
functionality
the
incompatibility
between
bactericidal
properties
biosafety
remain
great
challenges.
Herein,
multifunctional
polymer
coating
(CPB-Ac)
is
created,
incorporating
an
ultrasonic-responsive
carbon
monoxide
release
unit
(CORM-Ac)
antifouling
treat
catheter-related
As-synthesized
CPB-Ac
can
be
stably
anchored
various
with
arbitrary
shapes
compositions
via
facile
UV
treatment.
Both
in
vivo
vitro
experiments
demonstrated
that
this
multi-functional
exhibits
anti-fouling,
anti-inflammatory,
broad-spectrum
antibacterial
activities
well
good
biosafety.
During
initial
implantation
phase,
units
effectively
inhibit
attachment
contaminants,
significantly
reducing
risk
thrombosis
bacterial
infection.
Once
occurs,
ultrasonic
irradiation
activate
CO
much
higher
amount
55.3
µm
than
non-ultrasound
controls,
therefore
rapidly
eliminating
bacteria
alleviating
response.
It
believed
work
may
provide
effective
method
next-generation
intelligent
against
Nano-Micro Letters,
Год журнала:
2024,
Номер
17(1)
Опубликована: Окт. 17, 2024
The
incidence
of
large
bone
defects
caused
by
traumatic
injury
is
increasing
worldwide,
and
the
tissue
regeneration
process
requires
a
long
recovery
time
due
to
limited
self-healing
capability.
Endogenous
bioelectrical
phenomena
have
been
well
recognized
as
critical
biophysical
factors
in
remodeling
regeneration.
Inspired
bioelectricity,
electrical
stimulation
has
widely
considered
an
external
intervention
induce
osteogenic
lineage
cells
enhance
synthesis
extracellular
matrix,
thereby
accelerating
With
ongoing
advances
biomaterials
energy-harvesting
techniques,
electroactive
self-powered
systems
biomimetic
approaches
ensure
functional
recapitulating
natural
electrophysiological
microenvironment
healthy
tissue.
In
this
review,
we
first
introduce
role
bioelectricity
endogenous
electric
field
summarize
different
techniques
electrically
stimulate
Next,
highlight
latest
progress
exploring
hybrid
such
triboelectric
piezoelectric-based
nanogenerators
photovoltaic
cell-based
devices
their
implementation
engineering.
Finally,
emphasize
significance
simulating
target
tissue's
propose
opportunities
challenges
faced
bioelectronics
for
repair
strategies.
Abstract
Repairing
infected
bone
defects
is
hindered
by
the
presence
of
stubborn
bacterial
infections
and
inadequate
osteogenic
activity.
The
incorporation
harmful
antibiotics
not
only
fosters
emergence
multidrug‐resistant
bacteria,
but
also
diminishes
properties
scaffold
materials.
In
addition,
it
essential
to
continuously
monitor
degradation
kinetics
materials
at
defect
sites,
yet
majority
repair
lack
imaging
capability.
To
address
these
issues,
this
study
reports
for
first
time
development
a
single
nanomaterial
with
triple
functionality:
efficient
sonodynamic
antibacterial
activity,
accelerated
capability,
NIR
ability
visualized
therapy
defects.
Through
rationally
regulating
surface
functional
groups,
obtained
multifunctional
carbon
dots
(NIR‐CD)
exhibit
p–n
junction‐enhanced
narrow
bandgap‐facilitated
negative
charge‐augmented
validation
NIR‐CDs
activities
in
vivo
conducted
constructing
3D
injectable
hydrogels
encapsulated
(NIR‐CD/GelMA).
implantation
NIR‐CD/GelMA
hydrogel
scaffolds
model
MRSA‐infected
craniotomy
results
almost
complete
restoration
after
60
days.
These
findings
will
provide
traceable,
renewable,
repairable
candidate
biomaterials
tissue
engineering.
Advanced Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 31, 2025
Abstract
Bacterial
infection
has
become
the
most
dangerous
factor
in
tissue
repair,
which
strongly
affects
regeneration
efficiency
and
wellness
of
patients.
Piezoelectric
materials
exhibit
outstanding
advantage
producing
electrons
without
external
power
supply.
The
ability
electron
enrichment
reactive
oxygen
species
generation
through
noninvasive
stimulations
enables
piezoelectric
potential
applications
antibacterial.
Many
studies
have
proved
feasibility
as
a
functional
addition
antibacterial
biomaterial.
In
fact,
numerous
with
ingenious
designs
are
reported
to
be
effective
processes.
This
review
summarizes
mechanisms
piezoelectric,
illuminating
their
combating
bacteria.
Recent
advancement
design
construction
biomaterial
including
defect
engineering,
heterojunction,
synergy
metal
composite
scaffold
configuration
thoroughly
reviewed.
Moreover,
therapeutic
effects
common
tissues
requirements
introduced,
such
orthopedics,
dental,
wound
healing.
Finally,
development
prospects
points
deserving
further
exploration
listed.
is
expected
provide
valuable
insight
into
relationship
between
processes
materials,
inspiring
constructive
this
emerging
scientific
discipline.
RSC Advances,
Год журнала:
2025,
Номер
15(14), С. 10902 - 10957
Опубликована: Янв. 1, 2025
Strontium-based
nanoparticles
(SrNPs)
aid
bone
regeneration
and
combat
antimicrobial
resistance
by
enhancing
osteogenesis,
accelerating
healing,
targeting
resistant
pathogens.
