Antimicrobial Phenolic Materials: From Assembly to Function

Angewandte Chemie International Edition, Год журнала: 2025, Номер unknown

Опубликована: Фев. 5, 2025

Abstract Infectious diseases pose considerable challenges to public health, particularly with the rise of multidrug‐resistant pathogens that globally cause high mortality rates. These can persist on surfaces and spread in healthcare settings. Advances have been made developing antimicrobial materials reduce transmission pathogens, including composed naturally sourced polyphenols their derivatives, which exhibit potency, broad‐spectrum activity, a lower likelihood promoting resistance. This review provides an overview recent advances fabrication phenolic biomaterials, where natural compounds act as active agents or encapsulate other (e.g., metal ions, peptides, biopolymers). Various forms biomaterials synthesized through these two strategies, particles, capsules, hydrogels, coatings, are summarized, focus application wound healing, bone repair regeneration, oral coatings for medical devices. The potential advanced promising therapeutic approach combating antimicrobial‐resistant infections reducing microbial transmission.

Язык: Английский

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Enhancing Titanium Dioxide Nanotube Array Stability on Dental Implants through Laser Lithography–Assisted Microline Patterning

Acta Biomaterialia, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Antimicrobial Phenolic Materials: From Assembly to Function

Angewandte Chemie, Год журнала: 2025, Номер unknown

Опубликована: Фев. 5, 2025

Abstract Infectious diseases pose considerable challenges to public health, particularly with the rise of multidrug‐resistant pathogens that globally cause high mortality rates. These can persist on surfaces and spread in healthcare settings. Advances have been made developing antimicrobial materials reduce transmission pathogens, including composed naturally sourced polyphenols their derivatives, which exhibit potency, broad‐spectrum activity, a lower likelihood promoting resistance. This review provides an overview recent advances fabrication phenolic biomaterials, where natural compounds act as active agents or encapsulate other (e.g., metal ions, peptides, biopolymers). Various forms biomaterials synthesized through these two strategies, particles, capsules, hydrogels, coatings, are summarized, focus application wound healing, bone repair regeneration, oral coatings for medical devices. The potential advanced promising therapeutic approach combating antimicrobial‐resistant infections reducing microbial transmission.

Язык: Английский

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Multifunctional Hydroxyapatite/Tea Polyphenol Composite Coatings on Magnesium Alloy Surfaces for Enhancing Corrosion Resistance and Antibacterial Properties

Опубликована: Янв. 1, 2025

Язык: Английский

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Nanomaterials‐Based Drug Delivery Systems for Therapeutic Applications in Osteoporosis

Advanced Biology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 8, 2025

Abstract The etiology of osteoporosis is rooted in the disruption intricate equilibrium between bone formation and resorption processes. Nevertheless, conventional anti‐osteoporotic medications hormonal therapeutic regimens currently employed clinical practice are associated with a multitude adverse effects, thereby constraining their overall efficacy potential. Recently, nanomaterials have emerged as promising alternative due to minimal side efficient drug delivery, ability enhance formation, aiding restoring balance. This review delves into fundamental principles remodeling microenvironment, well current treatment approaches for osteoporosis. It subsequently explores research status nanomaterial‐based delivery systems treatment, encompassing inorganic nanomaterials, organic cell‐mimicking carriers exosomes mimics emerging therapies targeting microenvironment. Finally, discusses potential nanomedicine treating outlines future trajectory this burgeoning field. aim provide comprehensive reference application strategies therapy, fostering further advancements innovations critical area medical

Язык: Английский

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Hollow-whisker modified calcium phosphate loaded with deferoxamine to promote osteoporotic bone regeneration by acting HIF-1α signaling pathway

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 162444 - 162444

Опубликована: Апрель 1, 2025

Язык: Английский

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Metal-Phenolic Network Biointerface-mediated Cell Regulation for Bone Tissue Regeneration

Materials Today Bio, Год журнала: 2024, Номер 30, С. 101400 - 101400

Опубликована: Дек. 12, 2024

Язык: Английский

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Phloridzin functionalized gelatin-based scaffold for bone tissue engineering

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 279, С. 135224 - 135224

Опубликована: Авг. 30, 2024

Язык: Английский

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A Cross-Linked Coating Loaded with Antimicrobial Peptides for Corrosion Control, Early Antibacterial, and Sequential Osteogenic Promotion on a Magnesium Alloy as Orthopedic Implants

Acta Biomaterialia, Год журнала: 2024, Номер unknown

Опубликована: Дек. 1, 2024

Язык: Английский

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