Science and Technology of Engineering Chemistry and Environmental Protection,
Год журнала:
2024,
Номер
1(10)
Опубликована: Дек. 31, 2024
mwymwAbstract:In
recent
years,
flexible
wearable
sensors
have
received
widespread
attention
for
their
potential
application
value
in
motion
monitoring,
healthcare
and
human-computer
interaction.
Graphene,
as
a
two-dimensional
zero-bandgap
semi-metallic
material,
is
an
ideal
material
the
preparation
of
due
to
its
high
carrier
mobility,
mechanical
flexibility,
biocompatibility.
Based
on
target
species
performance
requirements,
researchers
utilize
graphene
redox
products
form
carbon
nanocomposites
by
combining
them
with
polymers,
metals
other
substrates
through
specific
methods.
This
helps
increase
number
active
sites
functional
groups
modified
graphene,
achieving
dispersion
functionalization
graphene.
Such
materials
can
effectively
solve
current
problems
low
sensitivity
poor
sustainability
faced
pure
field
promote
maturity
next-generation
electronic
diversified
directions.
review
starts
from
types
classic
methods
composites.
Then
it
elaborates
principles
applications
existing
pressure/strain,
biological,
humidity
composites
based
sensors.
Finally,
paper
comprehensively
summaries
challenges
at
present
stage
proposes
future
development
trends.
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 10, 2025
Abstract
Biological
Field
Effect
Transistors
(Bio‐FETs)
are
redefining
the
standard
of
biosensing
by
enabling
label‐free,
real‐time,
and
extremely
sensitive
detection
biomolecules.
At
center
this
innovation
is
fundamental
empowering
role
advanced
materials,
such
as
graphene,
molybdenum
disulfide,
carbon
nanotubes,
silicon.
These
when
harnessed
with
downstream
biomolecular
probes
like
aptamers,
antibodies,
enzymes,
allow
Bio‐FETs
to
offer
unrivaled
sensitivity
precision.
This
review
an
exposition
how
advancements
in
materials
science
have
permitted
detect
biomarkers
low
concentrations,
from
femtomolar
attomolar
levels,
ensuring
device
stability
reliability.
Specifically,
examines
incorporation
cutting‐edge
architectures,
flexible
/
stretchable
multiplexed
designs,
expanding
frontiers
contributing
development
more
adaptable
user‐friendly
Bio‐FET
platforms.
A
key
focus
placed
on
synergy
artificial
intelligence
(AI),
Internet
Things
(IoT),
sustainable
approaches
fast‐tracking
toward
transition
research
into
practical
healthcare
applications.
The
also
explores
current
challenges
material
reproducibility,
operational
durability,
cost‐effectiveness.
It
outlines
targeted
strategies
address
these
hurdles
facilitate
scalable
manufacturing.
By
emphasizing
transformative
played
their
cementing
position
Bio‐FETs,
positions
a
cornerstone
technology
for
future
solution
precision
would
lead
era
where
herald
massive
strides
biomedical
diagnostics
subsume.
Biosensors,
Год журнала:
2025,
Номер
15(5), С. 269 - 269
Опубликована: Апрель 24, 2025
Colloidal
quantum
dots
(QDs)
and
graphene
hybrids
have
emerged
as
promising
platforms
for
optoelectronic
biosensing
applications
due
to
their
unique
photophysical
electronic
properties.
This
study
investigates
the
fundamental
mechanism
underlying
photoluminescence
(PL)
quenching
recovery
in
graphene–QD
hybrid
systems
using
single-layer
field-effect
transistors
(SLG-FETs)
time-resolved
(TRPL)
spectroscopy.
We
demonstrate
that
PL
its
are
primarily
driven
by
charge
transfer,
evidenced
an
unchanged
fluorescence
lifetime
upon
quenching.
Density
functional
theory
calculations
reveal
a
significant
redistribution
at
interface,
corroborating
experimental
observations.
also
provide
simple
analytical
mechanical
model
differentiate
transfer-induced
from
resonance
energy
transfer.
Furthermore,
we
leverage
transfer
ultrasensitive
detect
biomarkers
such
immunoglobulin
G
(IgG)
femtomolar
concentrations.
The
sensor’s
electrical
response,
characterized
systematic
shifts
Dirac
point
of
SLG-FETs,
confirms
role
analyte-induced
modulation
recovery.
Our
findings
framework
designing
next-generation
graphene-based
biosensors
with
exceptional
sensitivity
specificity.
Nano-Micro Letters,
Год журнала:
2025,
Номер
17(1)
Опубликована: Апрель 30, 2025
Abstract
Amplification-free,
highly
sensitive,
and
specific
nucleic
acid
detection
is
crucial
for
health
monitoring
diagnosis.
The
type
III
CRISPR-Cas10
system,
which
provides
viral
immunity
through
CRISPR-associated
protein
effectors,
enables
a
new
amplification-free
diagnostic
tool.
In
this
study,
we
develop
CRISPR-graphene
field-effect
transistors
(GFETs)
biosensor
by
combining
the
system
with
GFETs
direct
detection.
This
exploits
target
RNA-activated
continuous
ssDNA
cleavage
activity
of
dCsm3
effector
high
charge
density
hairpin
DNA
reporter
on
GFET
channel
to
achieve
label-free,
amplification-free,
RNA
CRISPR-GFET
exhibits
excellent
performance
in
detecting
medium-length
RNAs
miRNAs,
limits
at
aM
level
broad
linear
range
10
−15
−11
M
−9
miRNAs.
It
shows
sensitivity
throat
swabs
serum
samples,
distinguishing
between
healthy
individuals
(N
=
5)
breast
cancer
patients
6)
without
need
extraction,
purification,
or
amplification.
platform
mitigates
risks
associated
amplification
cross-contamination,
making
it
versatile
scalable
tool
molecular
diagnostics
human
health.
Nano-Micro Letters,
Год журнала:
2025,
Номер
17(1)
Опубликована: Май 3, 2025
Abstract
Over
recent
decades,
carbon-based
chemical
sensor
technologies
have
advanced
significantly.
Nevertheless,
significant
opportunities
persist
for
enhancing
analyte
recognition
capabilities,
particularly
in
complex
environments.
Conventional
monovariable
sensors
exhibit
inherent
limitations,
such
as
susceptibility
to
interference
from
coexisting
analytes,
which
results
response
overlap.
Although
arrays,
through
modification
of
multiple
sensing
materials,
offer
a
potential
solution
recognition,
their
practical
applications
are
constrained
by
intricate
material
processes.
In
this
context,
multivariable
emerged
promising
alternative,
enabling
the
generation
outputs
construct
comprehensive
space
while
utilizing
single
material.
Among
various
carbon
nanotubes
(CNTs)
and
graphene
ideal
candidates
constructing
high-performance
sensors,
owing
well-established
batch
fabrication
processes,
superior
electrical
properties,
outstanding
capabilities.
This
review
examines
progress
focusing
on
CNTs/graphene
materials
field-effect
transistors
transducers
recognition.
The
discussion
encompasses
fundamental
aspects
these
including
architectures,
performance
metrics,
pattern
algorithms,
mechanism.
Furthermore,
highlights
innovative
extraction
schemes
when
integrated
with
algorithms.
This
paper
provides
a
comprehensive
review
of
the
latest
research
advancements
in
overcoming
Debye
screening
effect
field-effect
transistor
(FET)
sensors.
Sensors & Diagnostics,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
The
diagnostic
flow
of
the
GFET
sensor
for
viruses.
modified
aptamers
bind
to
target,
resulting
in
rearrangement
surface
charges
and
changes
graphene
carrier
mobility.
This
interaction
causes
a
shift
Dirac
point.
Science and Technology of Engineering Chemistry and Environmental Protection,
Год журнала:
2024,
Номер
1(10)
Опубликована: Дек. 31, 2024
mwymwAbstract:In
recent
years,
flexible
wearable
sensors
have
received
widespread
attention
for
their
potential
application
value
in
motion
monitoring,
healthcare
and
human-computer
interaction.
Graphene,
as
a
two-dimensional
zero-bandgap
semi-metallic
material,
is
an
ideal
material
the
preparation
of
due
to
its
high
carrier
mobility,
mechanical
flexibility,
biocompatibility.
Based
on
target
species
performance
requirements,
researchers
utilize
graphene
redox
products
form
carbon
nanocomposites
by
combining
them
with
polymers,
metals
other
substrates
through
specific
methods.
This
helps
increase
number
active
sites
functional
groups
modified
graphene,
achieving
dispersion
functionalization
graphene.
Such
materials
can
effectively
solve
current
problems
low
sensitivity
poor
sustainability
faced
pure
field
promote
maturity
next-generation
electronic
diversified
directions.
review
starts
from
types
classic
methods
composites.
Then
it
elaborates
principles
applications
existing
pressure/strain,
biological,
humidity
composites
based
sensors.
Finally,
paper
comprehensively
summaries
challenges
at
present
stage
proposes
future
development
trends.
