Journal of Materials Chemistry B,
Год журнала:
2023,
Номер
11(27), С. 6201 - 6224
Опубликована: Янв. 1, 2023
This
review
article
provides
an
overview
of
types
wound
dressings,
wound-dressing
materials,
advanced
fabrication
techniques,
and
key
features
applications
transparent
dressings
for
the
healing
process,
as
well
how
they
can
improve
outcomes.
Asian Journal of Pharmaceutical Sciences,
Год журнала:
2022,
Номер
17(3), С. 353 - 384
Опубликована: Янв. 24, 2022
Bacterial
infection
and
the
ever-increasing
bacterial
resistance
have
imposed
severe
threat
to
human
health.
And
contamination
could
significantly
menace
wound
healing
process.
Considering
sophisticated
process,
novel
strategies
for
skin
tissue
engineering
are
focused
on
integration
of
bioactive
ingredients,
antibacterial
agents
included,
into
biomaterials
with
different
morphologies
improve
cell
behaviors
promote
healing.
However,
a
comprehensive
review
anti-bacterial
dressing
enhance
has
not
been
reported.
In
this
review,
various
as
dressings
will
be
discussed.
Different
kinds
agents,
including
antibiotics,
nanoparticles
(metal
metallic
oxides,
light-induced
agents),
cationic
organic
others,
their
recent
advances
summarized.
Biomaterial
selection
fabrication
structures
forms,
films,
hydrogel,
electrospun
nanofibers,
sponge,
foam
three-dimension
(3D)
printed
scaffold
regeneration,
elaborated
Current
challenges
future
perspectives
presented
in
multidisciplinary
field.
We
envision
that
provide
general
insight
elegant
design
further
refinement
dressing.
Bioactive Materials,
Год журнала:
2021,
Номер
9, С. 461 - 474
Опубликована: Июль 26, 2021
Bacterial
infection,
tissue
hypoxia
and
inflammatory
response
can
hinder
the
infected
wound
repair
process.
To
mitigate
above
issues,
tannic
acid-chelated
Fe-decorated
molybdenum
disulfide
nanosheets
(MoS2@TA/Fe
NSs)
with
dual
enzyme
activities
were
developed
anchored
to
a
multifunctional
hydrogel.
The
hydrogel
exhibited
excellent
antibacterial
ability
owing
combined
effects
of
photothermal
therapy
(PTT),
glutathione
(GSH)
loss,
peroxidase
(POD)-like
activity
(catalyse
H2O2
into
·OH
under
acid
condition)
MoS2@TA/Fe
NSs.
Benefitting
from
catalase
(CAT)-like
activity,
could
decompose
O2
at
neutral
pH
relieve
supply
adequate
O2.
POD-like
was
mainly
attributed
MoS2
NSs,
while
CAT-like
primarily
due
TA/Fe
complex.
Moreover,
NSs
endowed
outstanding
anti-oxidant
scavenge
redundant
reactive
oxygen
species
(ROS)
nitrogen
(RNS)
environment
maintain
balance
antioxidant
systems
prevent
inflammation.
In
addition,
inhibit
release
factors
for
anti-inflammatory
property
TA.
TA
retained
partial
phenolic
hydroxyl
groups,
which
cross-linked
network
structure
promoted
adhesion
hydrogels.
Due
dynamic
boron
ester
bonds
between
polyvinyl
alcohol
(PVA),
dextran
(Dex),
MoS2@TA/Fe,
borax,
demonstrated
fast
self-healing
rapid
shape
adaptability.
This
shape-adaptable
adhesive
fill
whole
closely
contact
wound,
ensuring
that
it
achieved
its
functions
maximum
efficiency.
nanozyme-anchored
showed
high
potential
bacteria-infected
healing.
Chemical Society Reviews,
Год журнала:
2022,
Номер
51(15), С. 6307 - 6416
Опубликована: Янв. 1, 2022
This
review
highlights
the
recent
advances
of
metalated
covalent
organic
frameworks,
including
synthetic
strategies
and
applications,
discusses
current
challenges
future
directions.
Advanced Healthcare Materials,
Год журнала:
2021,
Номер
10(13)
Опубликована: Май 29, 2021
Abstract
Chronic
wounds,
such
as
the
diabetic
ulcer
wounds
have
serious
effect
on
people's
lives,
and
can
even
lead
to
death.
Diabetic
are
different
from
normal
much
easier
be
infected
induce
oxidative
stress
due
special
surrounding
microenvironment,
which
makes
it
necessary
prepare
materials
with
antibacterial
property
antioxidant
activity
simultaneously.
The
molybdenum
disulfide‐ceria
(MoS
2
‐CeO
)
nanocomposite
possesses
both
photo‐thermal
therapy
(PTT)
capability
of
polyethylene
glycol
modified
disulfide
nanosheets
cerium
dioxide
nanoparticles
(CeO
NPs).
By
combining
inherent
CeO
NPs,
MoS
exhibits
excellent
PTT
against
gram‐positive
gram‐negative
bacteria
through
808
nm
laser
treatment,
thereby
reducing
risk
wound
infection.
Owing
abundant
oxygen
vacancies
in
Ce
3+
4+
transform
reversibly
endows
remarkable
ability
clear
away
excessive
reactive
species
around
promote
healing.
results
demonstrate
that
is
a
promising
class
for
clinical
treatment
chronic
especially
used
switch.
Chemical Reviews,
Год журнала:
2023,
Номер
123(22), С. 12371 - 12430
Опубликована: Авг. 24, 2023
Nowadays,
the
increasing
emergence
of
antibiotic-resistant
pathogenic
microorganisms
requires
search
for
alternative
methods
that
do
not
cause
drug
resistance.
Phototherapy
strategies
(PTs)
based
on
photoresponsive
materials
have
become
a
new
trend
in
inactivation
due
to
their
spatiotemporal
controllability
and
negligible
side
effects.
Among
those
phototherapy
strategies,
photocatalytic
antimicrobial
therapy
(PCAT)
has
emerged
as
an
effective
promising
strategy
recent
years.
In
process
treatment,
are
excited
by
different
wavelengths
lights
produce
reactive
oxygen
species
(ROS)
or
other
toxic
killing
various
microbes,
such
bacteria,
viruses,
fungi,
parasites,
algae.
Therefore,
this
review
timely
summarizes
latest
progress
PCAT
field,
with
emphasis
development
antimicrobials
(PCAMs),
underlying
mechanisms,
design
multiple
practical
applications
local
infections
therapy,
personal
protective
equipment,
water
purification,
coatings,
wound
dressings,
food
safety,
antibacterial
textiles,
air
purification.
Meanwhile,
we
also
present
challenges
perspectives
widespread
implementation
therapeutics.
We
hope
result
review,
will
flourish
weapon
against
antibiotic
Journal of the American Chemical Society,
Год журнала:
2021,
Номер
143(43), С. 17891 - 17909
Опубликована: Окт. 22, 2021
The
emergence
of
multi-drug-resistant
pathogens
threatens
the
healthcare
systems
world-wide.
Recent
advances
in
phototherapy
(PT)
approaches
mediated
by
photo-antimicrobials
(PAMs)
provide
new
opportunities
for
current
serious
antibiotic
resistance.
During
PT
treatment,
reactive
oxygen
species
or
heat
produced
PAMs
would
react
with
cell
membrane,
consequently
leaking
cytoplasm
components
and
effectively
eradicating
different
like
bacteria,
fungi,
viruses,
even
parasites.
This
Perspective
will
concentrate
on
development
organic
(OPAMs)
their
application
as
practical
therapeutic
agents
into
therapy
local
infections,
wound
dressings,
removal
biofilms
from
medical
devices.
We
also
discuss
how
to
design
highly
efficient
OPAMs
modifying
chemical
structure
conjugating
a
targeting
component.
Moreover,
this
provides
discussion
general
challenges
direction
what
further
needs
be
done.
It
is
hoped
that
through
overview,
can
prosper
more
widely
used
microbial
infections
future,
especially
at
time
when
global
COVID-19
epidemic
getting
serious.
Chemodynamic
therapy
(CDT),
which
induces
cell
death
by
decomposing
high
levels
of
H2
O2
in
tumor
cells
into
highly
toxic
·OH,
is
recognized
as
a
promising
antineoplastic
approach.
However,
current
CDT
approaches
are
often
restricted
the
controlled
and
upregulated
cellular
antioxidant
defense.
To
enhance
·OH-induced
damage
CDT,
covalent
organic
framework
(COF)-based,
ferrocene
(Fc)-
glutathione
peroxidase
4
(GPX4)
inhibitor-loaded
nanodrug,
RSL3@COF-Fc
(2b),
fabricated.
The
obtained
2b
not
only
promotes
situ
Fenton-like
reactions
to
trigger
·OH
production
cells,
but
also
attenuates
repair
mechanisms
under
oxidative
stress
via
irreversible
GPX4
inhibition.
As
result,
these
two
synergistically
result
massive
lipid
peroxide
accumulation,
subsequent
damage,
ultimately
ferroptosis,
while
being
limited
intracellular
glutathione.
It
believed
that
this
research
provides
paradigm
for
enhancing
reactive
oxygen
species-mediated
oncotherapy
through
redox
dyshomeostasis
may
provide
new
insights
developing
COF-based
nanomedicine.
Chemical Society Reviews,
Год журнала:
2021,
Номер
51(1), С. 43 - 56
Опубликована: Дек. 3, 2021
Porous
organic
polymers
(POPs)
are
prepared
by
crosslinked
polymerization
of
multidimensional
rigid
aromatic
building
blocks
followed
PSM
depending
on
the
application.
ACS Applied Materials & Interfaces,
Год журнала:
2021,
Номер
13(23), С. 26651 - 26672
Опубликована: Июнь 4, 2021
Visible-light
irradiation
of
porphyrin
and
metalloporphyrin
dyes
in
the
presence
molecular
oxygen
can
result
photocatalytic
generation
singlet
(1O2).
This
type
II
reactive
species
(ROS)
finds
many
applications
where
dye,
also
called
photosensitizer,
is
dissolved
(i.e.,
homogeneous
phase)
along
with
substrate
to
be
oxidized.
In
contrast,
metal-organic
frameworks
(MOFs)
are
insoluble
(or
will
disassemble)
when
placed
a
solvent.
When
stable
as
suspension,
MOFs
adsorb
large
amount
O2
photocatalytically
generate
1O2
heterogeneous
process
efficiently.
Considering
immense
surface
area
great
capacity
for
gas
adsorption
MOFs,
they
seem
ideal
candidates
this
application.
Very
recently,
covalent-organic
(COFs),
variants
reticulation
relies
on
covalent
rather
than
coordination
bonds,
have
emerged
efficient
photosensitizers.
comprehensive
mini
review
describes
recent
developments
use
porphyrin-based
or
porphyrin-containing
COFs,
including
nanosized
versions,
photosensitizers
toward
antimicrobial
applications.