Seminars in Cancer Biology, Год журнала: 2023, Номер 90, С. 73 - 100
Опубликована: Фев. 10, 2023
Язык: Английский
Life Sciences, Год журнала: 2022, Номер 300, С. 120574 - 120574
Опубликована: Апрель 23, 2022
Язык: Английский
Процитировано
64
Frontiers in Bioengineering and Biotechnology, Год журнала: 2022, Номер 10
Опубликована: Авг. 16, 2022
Liposomes are the earliest and most widely used nanoparticles for targeted drug delivery. Exosomes nanosized membrane-bound particles important mediators of intercellular communication. Combining liposomes exosomes using various membrane fusion methods gives rise to a novel potential delivery system called fusion-based hybrid (MFHE). These MFHEs not only exhibit advantageous features, such as high loading rate cellular uptake via surface modification, but also endowed with biocompatibility low immunogenicity. Here, we provide an overview MFHEs’ preparation methods, characterization strategies, their applications disease treatment scientific research.
Язык: Английский
Процитировано
61
RSC Advances, Год журнала: 2022, Номер 12(29), С. 18475 - 18492
Опубликована: Янв. 1, 2022
In the past few decades, scientists have actively worked on developing effective drug delivery systems (DDSs) as means to control life-threatening diseases and challenging illnesses.
Язык: Английский
Процитировано
48
Pharmaceutics, Год журнала: 2022, Номер 14(2), С. 267 - 267
Опубликована: Янв. 23, 2022
The continuous technological advancement of nanomedicine has enabled the development novel vehicles for effective delivery therapeutic substances. Synthetic drug systems are nano-sized carriers made from various materials that can be designed to deliver cargoes cells or tissues. However, rapid clearance by immune system and poor targeting profile synthetic examples pressing obstacles faced in nanomedicine, which have directed field toward alternative strategies. Extracellular vesicles (EVs) nanoscale particles enclosed a protein-rich lipid bilayer; they released considered important mediators intercellular communication. Owing their natural composition, EVs been suggested exhibit good biocompatibility possess homing properties specific cell types. Combining with nanoparticles defined hybridization steps gives rise potential tool, i.e., EV-based hybrid systems. These advantageous features as compared such enhanced cellular uptake cargo delivery, immuno-evasive properties, capability crossing biological barriers, tissue profile. Here, we provide an overview strategies practiced produce elucidate those obtained upon EVs.
Язык: Английский
Процитировано
43
Seminars in Cancer Biology, Год журнала: 2023, Номер 90, С. 73 - 100
Опубликована: Фев. 10, 2023
Язык: Английский
Процитировано
42