ABSTRACT
The
food
application
of
natural
blue
colorants
such
as
acylated
anthocyanin
is
becoming
increasingly
popular
due
to
their
safety,
nutritional
value,
organoleptic
attributes,
and
more
pH/thermo‐stable
properties
compared
nonacylated
anthocyanins.
However,
it
a
great
challenge
obtain
enough
anthocyanins
meet
market
demand,
rather
than
readily
available
in
nature
from
edible
fruits
vegetables.
In
this
review,
the
crops,
efficient
eco‐friendly
extraction
food‐grade
anthocyanins,
potential
intelligent
packaging
are
extensively
summarized.
Subsequently,
plant
acyltransferases
(AATs)
also
comprehensively
strategy
functional
optimization
AATs
through
computational
or
artificial
intelligence–based
protein‐directed
evolution
described
suggested.
Additionally,
advantages
disadvantages
generated
microbes
suspension
cells
compared,
chassis
selection
engineering
discussed.
Finally,
approaches
strategies
metabolic
enhance
yield
Taken
together,
review
provides
roadmap
for
production
increasing
demand
future
industry.
Advanced Healthcare Materials,
Год журнала:
2023,
Номер
12(25)
Опубликована: Авг. 3, 2023
Anthocyanin,
a
unique
natural
polyphenol,
is
abundant
in
plants
and
widely
utilized
biomedicine,
cosmetics,
the
food
industry
due
to
its
excellent
antioxidant,
anticancer,
antiaging,
antimicrobial,
anti-inflammatory
properties.
However,
degradation
of
anthocyanin
an
extreme
environment,
such
as
alkali
pH,
high
temperatures,
metal
ions,
limits
physiochemical
stabilities
bioavailabilities.
Encapsulation
combining
with
biomaterials
could
efficiently
stabilize
for
protection.
Promisingly,
or
artificially
designed
proteins
peptides
favorable
stabilities,
biocapacity,
wide
sources
are
potential
candidates
anthocyanin.
This
review
focuses
on
recent
progress,
strategies,
perspectives
protein
peptide
functionalization
delivery,
i.e.,
formulation
technologies,
physicochemical
stability
enhancement,
cellular
uptake,
bioavailabilities,
biological
activities
development.
Interestingly,
simplicity
diversity
structure,
interaction
mechanisms
between
be
illustrated.
work
sheds
light
mechanism
protein/peptide-anthocyanin
nanoparticle
construction
expands
applications
nutrition
biomedicine.
Molecules,
Год журнала:
2024,
Номер
29(12), С. 2815 - 2815
Опубликована: Июнь 13, 2024
Anthocyanins,
as
the
most
critical
water-soluble
pigments
in
nature,
are
widely
present
roots,
stems,
leaves,
flowers,
fruits,
and
fruit
peels.
Many
studies
have
indicated
that
anthocyanins
exhibit
various
biological
activities
including
antioxidant,
anti-inflammatory,
anti-tumor,
hypoglycemic,
vision
protection,
anti-aging.
Hence,
used
food,
medicine,
cosmetics.
The
green
efficient
extraction
purification
of
an
important
prerequisite
for
their
further
development
utilization.
However,
poor
stability
low
bioavailability
limit
application.
Protein,
one
three
essential
nutrients
human
body,
has
good
biocompatibility
biodegradability.
Proteins
commonly
food
processing,
but
functional
properties
need
to
be
improved.
Notably,
can
interact
with
proteins
through
covalent
non-covalent
means
during
which
effectively
improve
enhance
bioavailability.
Moreover,
interactions
between
also
characteristics
nutritional
quality
proteins.
this
article
systematically
reviews
methods
anthocyanins.
review
summarizes
effect
on
impact
protein
properties.
Furthermore,
we
introduce
application
interaction
findings
provide
a
theoretical
reference
deep
processing.
Frontiers in Immunology,
Год журнала:
2024,
Номер
15
Опубликована: Авг. 23, 2024
Inflammation
is
a
normal
immune
response
in
organisms,
but
it
often
triggers
chronic
diseases
such
as
colitis
and
arthritis.
Currently,
the
most
widely
used
anti-inflammatory
drugs
are
non-steroidal
drugs,
albeit
they
accompanied
by
various
adverse
effects
hypertension
renal
dysfunction.
Bioactive
peptides
(BAPs)
provide
therapeutic
benefits
for
inflammation
mitigate
side
effects.
Herein,
this
review
focuses
on
of
BAPs
different
body
parts.
Emphasis
placed
immunomodulatory
mechanisms
treating
inflammation,
regulating
release
inflammatory
mediators,
modulating
MAPK
NF-κB
signaling
pathways,
reducing
oxidative
stress
reactions
immunomodulation.
This
aims
to
reference
function,
application,
anti-inflammation
BAPs.
Food Chemistry X,
Год журнала:
2024,
Номер
23, С. 101645 - 101645
Опубликована: Июль 14, 2024
The
instability
of
anthocyanins
significantly
reduces
their
bioavailability
as
food
nutrients.
This
proof-of-concept
study
aimed
to
develop
efficient
carriers
for
overcome
this
challenge.
Characterization
the
hydrogels
via
SEM
(scanning
electron
microscope)
and
rheological
analysis
revealed
formation
typical
gel
structures.
MTT
(methyl
thiazolyl
tetrazolium)
hemolysis
assays
confirmed
that
high
biocompatibility.
Encapsulation
efficiency
fluorescence
microscopy
images
demonstrated
successful
encapsulation
by
pH-responsive
hydrogels.
Stability
studies
further
validated
effect
peptide
in
helping
anthocyanin
molecules
withstand
factors
such
gastric
acid,
temperatures,
heavy
metals.
Subsequently,
responsive
simulated
(intestinal)
fluid
could
protect
from
acid
while
achieving
rapid
complete
release
intestinal
environments.
These
results
indicate
these
stabilize
facilitate
controlled
release,
potentially
leading
personalized
delivery
systems.
Foods,
Год журнала:
2024,
Номер
13(16), С. 2596 - 2596
Опубликована: Авг. 19, 2024
Bioactive
compounds
(BACs)
have
attracted
much
attention
due
to
their
potential
health
benefits.
However,
such
substances
problems
as
difficulty
dissolving
in
water,
poor
stability,
and
low
intestinal
absorption,
leading
serious
limitations
practical
applications.
Nowadays,
food
colloidal
delivery
carriers
become
a
highly
promising
solution
safety,
controllability,
efficiency.
The
use
of
natural
macromolecules
construct
can
not
only
regulate
the
solubility,
absorption
BACs
but
also
effectively
enhance
nutritional
added
value
functional
foods,
improve
sensory
properties,
extend
shelf
life.
Moreover,
smart-responsive
control
release
characteristics
BACs,
thus
improving
rate
human
body.
This
review
describes
several
typical
colloid
carriers,
focuses
on
physical
properties
from
static
structure
dynamic
release,
summarizes
applications
systems,
provides
an
outlook
future
development
carriers.
different
compositions
structures
colloids
tend
affect
stability
behaviors,
surface
rheological
predestine
application
scenarios.
vivo
effect
media
should
be
emphasized
exploration
safer
more
controllable
carrier
systems.
Sustainability,
Год журнала:
2023,
Номер
15(22), С. 16053 - 16053
Опубликована: Ноя. 17, 2023
Silk
secreted
by
Bombyx
mori
L.
silkworm
has
become
one
of
the
most
important
biomaterials,
due
to
its
excellent
biocompatibility,
controllable
biodegradability,
superior
processability,
and
unique
mechanical
properties.
fibroin
sericin,
as
two
components
silk,
contain
abundant
polar
functional
groups,
thus
can
bind
metal
ions
through
electrostatic
interaction
chelation.
Based
on
this
binding,
silk
proteins
not
only
be
used
fabricate
ecofriendly
efficient
adsorbents
remove
heavy
metals
from
waterbodies,
but
also
synthesize
nanostructures
(nanoparticles
or
nanoclusters)
form
silk/metal
composites
with
amazing
optical
electrochemical
characteristics.
This
binding
manipulated
optimize
silk’s
performance.
review
focuses
discussing
summarizing
advances
in
use
sericin
for
ion-contaminated
water
remediation,
biosensing
materials,
materials
perspective
between
ions.
The
performance
enhancement
using
is
analyzed.
Moreover,
proteins’
interactions
related
structural
features
that
contribute
above
sustainable
applications
are
illustrated
lay
a
theoretical
foundation.
will
favor
expansion
both
traditional
textile
field
new
biomaterials.
