Natural Regenerative Hydrogels for Wound Healing

Gels, Год журнала: 2024, Номер 10(9), С. 547 - 547

Опубликована: Авг. 23, 2024

Regenerative hydrogels from natural polymers have come forth as auspicious materials for use in regenerative medicine, with interest attributed to their intrinsic biodegradability, biocompatibility, and ability reassemble the extracellular matrix. This review covers latest advances used wound healing, focusing on chemical composition, cross-linking mechanisms, functional properties. Key carbohydrate polymers, including alginate, chitosan, hyaluronic acid, polysaccharide gums, agarose, carrageenan, xanthan gum, are discussed terms of sources, structures specific properties suitable applications. The further explores categorization based ionic charge, response physiological stimuli (i.e., pH, temperature) particularized roles tissue self-healing. Various methods enhance mechanical biological performance these also examined. By highlighting recent innovations ongoing challenges, this article intends give a detailed understanding potential revolutionize medicine improve patient healing outcomes.

Язык: Английский

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Ionic microsphere therapy for skin trauma

APL Materials, Год журнала: 2024, Номер 12(10)

Опубликована: Окт. 1, 2024

The skin is an important barrier for the body. Normal wound healing can be severely impeded by inadequate angiogenesis, excessive inflammation, and increased susceptibility to infection. Therefore, effective therapy should focus on accelerating process providing antimicrobial properties that are essential recovery. Alginate (ALG) a biocompatible polysaccharide substance capable of forming hydrogel dressings cross-linking with metal ions, especially Zn2+, Fe3+, Cu2+, Ca2+ ions. formed them gradually release during repair, which has role in promoting angiogenesis collagen deposition. Here, we prepared microspheres (MS) based different ions such as Zn-MS, Fe-MS, Cu-MS, Ca-MS investigated effect these healing. In vitro vivo experiments showed MS Zn2+ enhanced activity, Fe3+ Cu2+ formation fibers, promoted development capillaries. So, ALG four great significance research value field application.

Язык: Английский

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Preparation, characterization, multidimensional applications and prospects of protein bio-based hydrogels: A review

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 144199 - 144199

Опубликована: Май 1, 2025

Язык: Английский

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Self-Assembling Peptide Hydrogels: Design, Mechanisms, Characterization, and Biomedical Applications

Soft Matter, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Structural characteristics, molecular driving forces, and medical applications of multifunctional peptide-based biomaterial hydrogels.

Язык: Английский

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Multifaceted Role of Nanocomposite Hydrogels in Diabetic Wound Healing: Enhanced Biomedical Applications and Detailed Molecular Mechanisms

Biomaterials Science, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Nanocomposite hydrogels offer a promising approach to treating diabetic wounds. Key findings include enhanced mechanical properties, antibacterial effects, and the ability regulate wound microenvironment.

Язык: Английский

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