Cited by Multifaceted Role of Nanocomposite Hydrogels in Diabetic Wound Healing: Enhanced Biomedical Applications and Detailed Molecular Mechanisms

Natural Regenerative Hydrogels for Wound Healing DOI

Mariana Chelu,

José María Calderón Moreno,

Adina Magdalena Musuc

et al.

Gels, Journal Year: 2024, Volume and Issue: 10(9), P. 547 - 547

Published: Aug. 23, 2024

Regenerative hydrogels from natural polymers have come forth as auspicious materials for use in regenerative medicine, with interest attributed to their intrinsic biodegradability, biocompatibility, and ability reassemble the extracellular matrix. This review covers latest advances used wound healing, focusing on chemical composition, cross-linking mechanisms, functional properties. Key carbohydrate polymers, including alginate, chitosan, hyaluronic acid, polysaccharide gums, agarose, carrageenan, xanthan gum, are discussed terms of sources, structures specific properties suitable applications. The further explores categorization based ionic charge, response physiological stimuli (i.e., pH, temperature) particularized roles tissue self-healing. Various methods enhance mechanical biological performance these also examined. By highlighting recent innovations ongoing challenges, this article intends give a detailed understanding potential revolutionize medicine improve patient healing outcomes.

Language: Английский

Citations

Ionic microsphere therapy for skin trauma DOI

Jiayin Feng, Fangyan Wang,

Xiaoyi Pan

et al.

APL Materials, Journal Year: 2024, Volume and Issue: 12(10)

Published: Oct. 1, 2024

The skin is an important barrier for the body. Normal wound healing can be severely impeded by inadequate angiogenesis, excessive inflammation, and increased susceptibility to infection. Therefore, effective therapy should focus on accelerating process providing antimicrobial properties that are essential recovery. Alginate (ALG) a biocompatible polysaccharide substance capable of forming hydrogel dressings cross-linking with metal ions, especially Zn2+, Fe3+, Cu2+, Ca2+ ions. formed them gradually release during repair, which has role in promoting angiogenesis collagen deposition. Here, we prepared microspheres (MS) based different ions such as Zn-MS, Fe-MS, Cu-MS, Ca-MS investigated effect these healing. In vitro vivo experiments showed MS Zn2+ enhanced activity, Fe3+ Cu2+ formation fibers, promoted development capillaries. So, ALG four great significance research value field application.

Language: Английский

Citations

Preparation, characterization, multidimensional applications and prospects of protein bio-based hydrogels: A review DOI

Tianhao Zhang, Ruihan Zhang, Chunshun Zhao

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 144199 - 144199

Published: May 1, 2025

Language: Английский

Citations

Self-Assembling Peptide Hydrogels: Design, Mechanisms, Characterization, and Biomedical Applications DOI

Zhenhong Zhang, Jinhong Gao, Libo Yuan

et al.

Soft Matter, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Structural characteristics, molecular driving forces, and medical applications of multifunctional peptide-based biomaterial hydrogels.

Language: Английский

Citations

Multifaceted Role of Nanocomposite Hydrogels in Diabetic Wound Healing: Enhanced Biomedical Applications and Detailed Molecular Mechanisms DOI

Gege Xiong,

Qiwei Chen, Qiuyu Wang

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Nanocomposite hydrogels offer a promising approach to treating diabetic wounds. Key findings include enhanced mechanical properties, antibacterial effects, and the ability regulate wound microenvironment.

Language: Английский

Citations