International Journal of Pharmaceutics, Год журнала: 2024, Номер 669, С. 125101 - 125101
Опубликована: Дек. 19, 2024
Язык: Английский
International Journal of Pharmaceutics, Год журнала: 2024, Номер 669, С. 125101 - 125101
Опубликована: Дек. 19, 2024
Язык: Английский
Advanced Biology, Год журнала: 2025, Номер unknown
Опубликована: Апрель 9, 2025
Abstract Ferroptosis, as novel type of regulated cell death that has garnered widespread attention over the past decade, witnessed continuous discovery an increasing number regulatory mechanisms. Trace metal elements play a multifaceted and crucial role in oncology. Interestingly, it been increasingly evident these elements, such copper, are involved regulation iron accumulation, lipid peroxidation antiferroptotic systems, suggesting existence “nonferrous” mechanisms ferroptosis. In this review, comprehensive overview composition mechanism ferroptosis is provided. The interaction between copper metabolism (including cuproptosis) cancer, well roles other trace (such zinc, manganese, cobalt, molybdenum) specifically focused. Furthermore, applications nanomaterials based on metals cancer therapy also reviewed potential strategies for co‐targeting cuproptosis explored. Nevertheless, light intricate ambiguous nature interactions, ongoing research essential to further elucidate ferroptosis, thereby facilitating development therapeutic targets approaches treatment.
Язык: Английский
Процитировано
0Biomedicine & Pharmacotherapy, Год журнала: 2024, Номер 182, С. 117769 - 117769
Опубликована: Дек. 16, 2024
Язык: Английский
Процитировано
2Antioxidants and Redox Signaling, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 26, 2024
Vascular smooth muscle cell (VSMC) ferroptosis is a pivotal event in the process of aortic dissection (AD), and number agents have protective role against AD by inhibiting VSMC ferroptosis. While glycolysis an ancient pathway related to almost all biological processes, its precise involvement remains unclear.
Язык: Английский
Процитировано
0International Journal of Pharmaceutics, Год журнала: 2024, Номер 669, С. 125101 - 125101
Опубликована: Дек. 19, 2024
Язык: Английский
Процитировано
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