Advances in Manganese-based nanomaterials for cancer therapy via regulating Non-Ferrous ferroptosis DOI

Dipa Kusi,

Yan Sun,

Chenguang Liu

et al.

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 669, P. 125101 - 125101

Published: Dec. 19, 2024

Language: Английский

The Regulation of Trace Metal Elements in Cancer Ferroptosis DOI Creative Commons

Xiaoyan Wang,

Yuanyuan Xue, Lei Chang

et al.

Advanced Biology, Journal Year: 2025, Volume and Issue: unknown

Published: April 9, 2025

Abstract Ferroptosis, as novel type of regulated cell death that has garnered widespread attention over the past decade, witnessed continuous discovery an increasing number regulatory mechanisms. Trace metal elements play a multifaceted and crucial role in oncology. Interestingly, it been increasingly evident these elements, such copper, are involved regulation iron accumulation, lipid peroxidation antiferroptotic systems, suggesting existence “nonferrous” mechanisms ferroptosis. In this review, comprehensive overview composition mechanism ferroptosis is provided. The interaction between copper metabolism (including cuproptosis) cancer, well roles other trace (such zinc, manganese, cobalt, molybdenum) specifically focused. Furthermore, applications nanomaterials based on metals cancer therapy also reviewed potential strategies for co‐targeting cuproptosis explored. Nevertheless, light intricate ambiguous nature interactions, ongoing research essential to further elucidate ferroptosis, thereby facilitating development therapeutic targets approaches treatment.

Language: Английский

Citations

0
Ferroptosis in hepatocellular carcinoma: Mechanisms and therapeutic implications DOI Open Access

Shanjie Tu,

Yisheng Zou,

Meiqi Yang

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2024, Volume and Issue: 182, P. 117769 - 117769

Published: Dec. 16, 2024

Language: Английский

Citations

2
Lactate Dehydrogenase A Is a Novel Positive Regulator of Vascular Smooth Muscle Cell Ferroptosis During Aortic Dissection DOI
Feng Xin, Xin Yi, Bo Huo

et al.

Antioxidants and Redox Signaling, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 26, 2024

Vascular smooth muscle cell (VSMC) ferroptosis is a pivotal event in the process of aortic dissection (AD), and number agents have protective role against AD by inhibiting VSMC ferroptosis. While glycolysis an ancient pathway related to almost all biological processes, its precise involvement remains unclear.

Language: Английский

Citations

0
Advances in Manganese-based nanomaterials for cancer therapy via regulating Non-Ferrous ferroptosis DOI

Dipa Kusi,

Yan Sun,

Chenguang Liu

et al.

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 669, P. 125101 - 125101

Published: Dec. 19, 2024

Language: Английский

Citations

0