Cerium dioxide nanozyme doped hybrid hydrogel with antioxidant and antibacterial abilities for promoting diabetic wound healing

Chemical Engineering Journal, Год журнала: 2024, Номер 497, С. 154517 - 154517

Опубликована: Авг. 3, 2024

Язык: Английский

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Protocatechuic acid grafted chitosan/oxidized glucomannan hydrogel with antimicrobial and anti-inflammatory effects for enhancing wound repair

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 136514 - 136514

Опубликована: Окт. 14, 2024

Язык: Английский

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Light-triggered release of nitric oxide from chitosan-based cationic hydrogels for promoting infected wounds healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 304, С. 140998 - 140998

Опубликована: Фев. 12, 2025

Язык: Английский

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Polysaccharide-based aerogel dressing integrated with MOF-loaded quercetin with multifunctional effects for promoting infected wound healing

APL Materials, Год журнала: 2025, Номер 13(4)

Опубликована: Апрель 1, 2025

Infectious wounds disrupt the progression through stages of wound healing, resulting in development chronic wounds. However, current therapeutic approach is limited and requires repeated administrations. A major challenge infectious to achieve sustained drug release. Herein, quercetin with anti-inflammatory antibacterial properties was encapsulated within amino-functionalized UIO-66 metal-organic framework (MOF) form MOF@Que NPs. NPs were then loaded into an aerogel constructed agarose, aldehyde hyaluronic acid, carboxymethyl chitosan obtain ACA-MOF@Que for targeting different phases healing. The polysaccharide-based formed by entanglement polymer chains Schiff base reaction, which exhibited uniform pore structures low-swelling properties. Furthermore, also antioxidant, anti-inflammatory, In vivo vitro experiments confirmed that could promote hemostasis initial stage reduce cellular inflammatory infiltration, inhibit response regulating macrophage polarization during Finally, angiogenesis increase collagen deposition later Compared untreated group, rats treated had almost completely healed on 14th day. Therefore, plays multiple roles at various providing a promising clinical application

Язык: Английский

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Gelatin-based adaptive injectable nanocomposite hydrogel for closure of irregular wounds and immunoregulation in diabetic wound healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 144313 - 144313

Опубликована: Май 1, 2025

Язык: Английский

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Hyaluronic acid-based ε-polylysine/polyurethane asymmetric sponge for enhanced wound healing

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 136395 - 136395

Опубликована: Окт. 9, 2024

Язык: Английский

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Catalytic Biomaterials‐Activated In Situ Chemical Reactions: Strategic Modulation and Enhanced Disease Treatment

Advanced Materials, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 5, 2024

Abstract Chemical reactions underpin biological processes, and imbalances in critical biochemical pathways within organisms can lead to the onset of severe diseases. Within this context, emerging field “Nanocatalytic Medicine” leverages nanomaterials as catalysts modulate fundamental chemical specific microenvironments This approach is designed facilitate targeted synthesis localized accumulation therapeutic agents, thus enhancing treatment efficacy precision while simultaneously reducing systemic side effects. The effectiveness these nanocatalytic strategies critically hinges on a profound understanding kinetics intricate interplay particular pathological ensure effective catalytic actions. review methodically explores situ their associated biomaterials, emphasizing regulatory that control responses. Furthermore, discussion encapsulates crucial elements‐reactants, catalysts, reaction conditions/environments‐necessary for optimizing thermodynamics reactions, rigorously addressing both biophysical dimensions disease enhance outcomes. It seeks clarify mechanisms underpinning biomaterials evaluate potential revolutionize across various conditions.

Язык: Английский

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An antimicrobial and adhesive conductive chitosan quaternary ammonium salt hydrogel dressing for combined electrical stimulation and photothermal treatment to promote wound healing

Carbohydrate Polymers, Год журнала: 2024, Номер 351, С. 123136 - 123136

Опубликована: Дек. 11, 2024

Язык: Английский

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A sustained H2S-releasing nanocellulose-based hydrogel with anti-inflammatory and antibacterial properties for promoting infected wound healing

Carbohydrate Polymers, Год журнала: 2025, Номер 355, С. 123424 - 123424

Опубликована: Фев. 20, 2025

Язык: Английский

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Progress in Polysaccharide-Based Hydrogels for Preventing Postoperative Adhesions: A Review

Gels, Год журнала: 2025, Номер 11(3), С. 188 - 188

Опубликована: Март 8, 2025

Postoperative adhesions are common complications following surgery, often accompanied by pain and inflammation that significantly diminish patients’ quality of life. Moreover, managing postoperative incurs substantial cost, imposing a considerable financial burden on both patients healthcare systems. Traditional anti-adhesion materials confronted with limitations, such as inadequate tissue adherence in moist environment poor degradability, underscoring the urgent need for more effective solutions. Recently, polysaccharide-based hydrogels have received attention their potential preventing adhesions. The not only facilitate wound healing but also effectively reduce inflammation, providing promising approach to This review provides an extensive analysis progress made development therapy. It highlights principal benefits, outlines future research trajectories, addresses ongoing challenges be overcome.

Язык: Английский

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