An anticoagulant supercapacitor for implantable applications
Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Дек. 3, 2024
With
the
rapid
advancement
of
implantable
electronic
medical
devices,
supercapacitors
have
emerged
as
popular
energy
storage
devices.
However,
inevitably
come
into
direct
contact
with
blood
when
implanted,
potentially
causing
adverse
clinical
reactions
such
coagulation
and
thrombosis,
impairing
performance
implanted
posing
a
serious
threat
to
human
health.
Therefore,
this
work
aims
design
an
anticoagulant
supercapacitor
by
heparin
doped
poly(3,
4-ethylenedioxythiophene)
(PEDOT)
for
possible
applications
in
bioelectronics.
Heparin
(Hep),
as-known
macromolecule
acts
counterion
PEDOT
doping
enhance
its
conductivity,
bioelectrode
material
PEDOT:
Hep
activity
is
synthesized
via
chemical
oxidation
polymerization.
Concurrently,
constructed
through
in-situ
polymerization,
where
bacterial
cellulose
electrode
electrolyte
layer,
respectively.
Owing
incorporation
heparin,
exhibits
high
hemocompatibility
hemolysis
rate
<5
%,
good
time
63.4
s,
reasonable
cycle
stability
capacitance
retention
76.24
%
after
20,
000
cycles,
supplies
power
heart
sensors
female
mice.
This
provides
platform
electronics
achieve
vivo.
Implantable
are
promising
use
supply
devices
within
body,
but
their
utility
hindered
thrombosis.
Here,
authors
report
that
properties
cycling
stability.
Язык: Английский
Heparin Doped Polyaniline for Anticoagulation Supercapacitors
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 9, 2025
Abstract
With
the
rapid
development
of
implantable
electronic
medical
devices,
supercapacitors
have
gained
significant
attention
as
energy
storage
devices
due
to
their
inherent
advantages.
However,
these
inevitably
direct
contact
with
blood
and
trigger
coagulation
or
thrombus
formation
when
implanted
in
body.
In
severe
cases,
negative
effects
compromise
functionality
system
even
jeopardize
human
health.
Herein,
a
biocompatible
electrode
material
high
anticoagulant
activity
is
designed
by
doping
polyaniline
macromolecule
heparin
under
neutral
conditions,
which
macromolecules
dopants
conditions
not
only
avoids
toxicity
acids
biological
tissues
de‐doping
caused
small
molecules,
but
also
imparts
properties
material.
Based
on
situ
polymerization
approach,
an
all‐in‐one
anticoagulation
supercapacitor
employed
manufacture
exhibits
good
electrochemical
performance
(energy
density
18.89
µWh
cm
−2
power
197.8
µW
),
cycling
stability
(capacitance
retention
70.23%
after
2,
000
cycles),
(APTT
15.47
s,
PT
16.57
TT
49.47
FIB
1.12
g
L
−1
tissue
compatibility.
The
strategy
provides
valuable
reference
for
supply
bioelectronics.
Язык: Английский
Advanced implantable energy storage for powering medical devices
eScience,
Год журнала:
2025,
Номер
unknown, С. 100409 - 100409
Опубликована: Апрель 1, 2025
Язык: Английский
Vitamin C Secondary‐Doped Poly(3, 4‐ethylenedioxythiophene): Poly(Styrene Sulfonate) for Enhancing Conductivity and Biocompatibility for Implantation
Advanced Functional Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 2, 2025
Abstract
Poly(3,
4‐ethylenedioxythiophene):
poly(styrene
sulfonate)
(PEDOT:
PSS)
has
garnered
increasing
attention
due
to
its
adjustable
and
enhanced
electrical
conductivity
ease
of
processing.
However,
for
applications
in
bioelectronics
as
a
conductive
filler
the
preparation
hydrogels,
further
improvements
are
necessary.
In
this
study,
an
eco‐friendly
polar
additive,
vitamin
C
(VC),
is
introduced
simultaneously
enhance
biocompatibility
PEDOT:
PSS.
The
multiple
hydroxy
groups
VC
impart
polarity
facilitate
hydrogen
bonding
with
PSS,
thereby
removing
excess
non‐conductive
PSS
not
involved
polymerization
expanding
continuously
conducting
PEDOT‐rich
domains.
Importantly,
can
regulate
inflammatory
factors
by
reducing
reactive
oxygen
species
levels,
effectively
improving
biocompatibility.
Consequently,
secondary‐doped
shows
potential
diverse
properties,
solubility,
biocompatibility,
blood
compatibility.
A
hydrogel
prepared
incorporating
PSS‐VC
into
sodium
alginate
guar
gum
system.
Supercapacitors
anticoagulant
properties
assembled
address
thrombosis,
coagulation
risks,
responses
vivo.
This
doping
strategy
be
applied
develop
high‐performance,
biocompatible,
implantable
bioelectronics.
Язык: Английский
Ordered porous sulfonic acid MOFs doped poly(3, 4-ethylenedioxythiophene): Toward anticoagulant electrode materials and supercapacitors
Journal of Energy Storage,
Год журнала:
2024,
Номер
99, С. 113263 - 113263
Опубликована: Авг. 7, 2024
Язык: Английский
Poly(3, 4‐Ethylenedioxythiophene) as Promising Energy Storage Materials in Zinc‐Ion Batteries
Macromolecular Rapid Communications,
Год журнала:
2024,
Номер
45(23)
Опубликована: Окт. 29, 2024
Abstract
Benefiting
from
the
advantages
of
high
conductivity
and
good
electrochemical
stability,
conjugated
conducting
polymer
poly
(3,
4‐ethylenedioxythiophene)
is
a
promising
energy
storage
material
in
zinc‐ion
batteries.
Zinc‐ion
batteries
have
safety,
environmental
friendliness,
low
cost,
but
suffer
unstable
cathode
structure,
poor
electrical
conductivity,
uncontrollable
dendritic
growth
zinc
anodes.
PEDOT,
with
its
fast
response
wide
potential
window,
expected
to
make
up
for
shortcomings
enhance
capacity
cycle
life
Herein,
this
review
different
polymerization
methods
as
well
their
structure
properties
are
summarized;
progress
doping
strategies
related
increasing
dispersivity
materials
discussed;
specific
applications
4‐ethylenedioxythiophene)‐based
anode,
cathode,
electrolyte,
binder
explored;
representative
advancements
improving
performance
emphasized.
Finally,
current
challenges
an
insight
into
future
research
directions
pointed
out.
Язык: Английский