Advances in Research of Hydrogel Microneedle-Based Delivery Systems for Disease Treatment DOI Creative Commons
Juan Cao, Bo Wu, Ping Yuan

и другие.

Pharmaceutics, Год журнала: 2024, Номер 16(12), С. 1571 - 1571

Опубликована: Дек. 9, 2024

Microneedles (MNs), composed of multiple micron-scale needle-like structures attached to a base, offer minimally invasive approach for transdermal drug delivery by penetrating the stratum corneum and delivering therapeutic agents directly epidermis or dermis. Hydrogel microneedles (HMNs) stand out among various MN types due their excellent biocompatibility, high drug-loading capacity, tunable drug-release properties. This review systematically examines matrix materials fabrication methods HMN systems, highlighting advancements in natural synthetic polymers, explores applications treating conditions such as wound healing, hair loss, cardiovascular diseases, cancer. Furthermore, potential HMNs disease diagnostics is discussed. The identifies key challenges, including limited mechanical strength, efficiency, lack standardization, while proposing strategies overcome these issues. With integration intelligent design enhanced control over dosage safety, are poised revolutionize expand personalized medicine.

Язык: Английский

Recent progress in the 3D printing of microneedle patches for biomedical applications DOI
Huan Liu,

Aminov Nail,

Decheng Meng

и другие.

International Journal of Pharmaceutics, Год журнала: 2024, Номер unknown, С. 124995 - 124995

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

6

Wearable, battery-free, and wireless microneedle-based bioelectronics for robustly-integrated chronic wound management and therapeutic diagnosis DOI
Ying Liu, Xiaomin Luo, Liuying Li

и другие.

Nano Energy, Год журнала: 2025, Номер unknown, С. 110909 - 110909

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Microneedle-aided nanotherapeutics delivery and nanosensor intervention in advanced tissue regeneration DOI Creative Commons

Churong Xu,

Fei Wu,

Zhouyi Duan

и другие.

Journal of Nanobiotechnology, Год журнала: 2025, Номер 23(1)

Опубликована: Май 3, 2025

Язык: Английский

Процитировано

0

Buccal application of microneedles coated with an optimized hydrogel containing naproxen and dexamethasone DOI

Joo‐Young Kim,

Y. J. Um,

Young‐Guk Na

и другие.

Drug Delivery and Translational Research, Год журнала: 2025, Номер unknown

Опубликована: Май 5, 2025

Язык: Английский

Процитировано

0

Nanoscale coordination polymer-coated microneedle patches against bacterial biofilm infection via hypoxia-enhanced copper ion interference therapy DOI

Xinwei Fu,

D. C. Shan,

Jie Liang

и другие.

Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 158789 - 158789

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

1

Advances in Research of Hydrogel Microneedle-Based Delivery Systems for Disease Treatment DOI Creative Commons
Juan Cao, Bo Wu, Ping Yuan

и другие.

Pharmaceutics, Год журнала: 2024, Номер 16(12), С. 1571 - 1571

Опубликована: Дек. 9, 2024

Microneedles (MNs), composed of multiple micron-scale needle-like structures attached to a base, offer minimally invasive approach for transdermal drug delivery by penetrating the stratum corneum and delivering therapeutic agents directly epidermis or dermis. Hydrogel microneedles (HMNs) stand out among various MN types due their excellent biocompatibility, high drug-loading capacity, tunable drug-release properties. This review systematically examines matrix materials fabrication methods HMN systems, highlighting advancements in natural synthetic polymers, explores applications treating conditions such as wound healing, hair loss, cardiovascular diseases, cancer. Furthermore, potential HMNs disease diagnostics is discussed. The identifies key challenges, including limited mechanical strength, efficiency, lack standardization, while proposing strategies overcome these issues. With integration intelligent design enhanced control over dosage safety, are poised revolutionize expand personalized medicine.

Язык: Английский

Процитировано

0