Research Progress on the Exacerbation of Lipid Metabolism by Malassezia and Its Impact on the Skin Barrier Function
Cosmetics,
Год журнала:
2025,
Номер
12(2), С. 67 - 67
Опубликована: Апрель 3, 2025
The
study
of
the
fungal
communities
skin
constitutes
a
pivotal
component
microbiome
research.
Within
these
communities,
genus
Malassezia
stands
out
as
major
constituent,
representing
50%
to
80%
total
colonization
on
healthy
individuals.
excessive
growth
or
metabolic
irregularities
this
are
intimately
connected
with
onset
various
disorders
that
intrinsically
linked
its
lipid-dependent
nature.
Cutaneous
lipid
metabolism
is
indispensable
for
maintaining
barrier
function
and
health.
possesses
ability
encode
multiple
lipase
genes,
secretion
lipases
plays
role
in
survival
strategies
fungi.
This
review
explores
recent
advances
ecological
niche
microecological
homeostasis,
mechanism
disrupting
lipids
through
catabolic
metabolites,
relationship
between
disruption
diseases.
offers
reference
future
research
mechanisms
by
which
affects
provides
theoretical
foundation
development
innovative
therapeutic
approaches
dermatological
conditions.
Язык: Английский
Mild Phototherapy Strategies for Preventing Pathogen Infection and Enhancing Cell Proliferation in Diabetic Wound
Mingji Jiang,
Renhao Nie,
Jing Kang
и другие.
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 27, 2025
Abstract
Excessive
inflammation,
bacterial
infection,
and
impaired
cell
proliferation
posed
significant
challenges
to
diabetic
wound
healing.
There
is
an
urgent
need
for
effective
method
that
can
simultaneously
provide
antibacterial
activity
promote
facilitate
the
healing
of
bacteria‐infected
wounds.
In
this
study,
a
novel
nanoplatform,
GDYO‐VPIM‐Au
designed,
by
co‐decorating
1‐vinyl‐3‐pentylimidazolium
bromide
([VPIM]Br)
gold
nanorods
(Au
NRs)
on
graphdiyne
oxide
(GDYO)
nanosheets.
exhibited
excellent
properties
against
drug‐resistant
bacteria
through
reactive
oxygen
species
(ROS)
generation
electrostatic
interactions.
Moreover,
with
synergistic
effect
mild
phototherapy
therapy
(mPTT)
produced
Au
NRs
efficient
significantly
accelerate
infected
This
work
represented
promising
therapeutic
strategy
addressing
infections
enhancing
Язык: Английский
Lactobacillus plantarum in high methoxylated pectin-based encapsulation systems supports gut epithelial wound healing in vitro
Food Hydrocolloids for Health,
Год журнала:
2025,
Номер
unknown, С. 100218 - 100218
Опубликована: Май 1, 2025
Язык: Английский
Upcoming generation nanoengineered antimicrobial delivery system for targeting multidrug-resistant microbes
Critical Reviews in Biotechnology,
Год журнала:
2025,
Номер
unknown, С. 1 - 20
Опубликована: Июнь 2, 2025
The
rise
of
chronic
and
acute
infections
has
increased
reliance
on
antimicrobial
agents.
However,
conventional
antimicrobials
often
fail
to
deliver
optimal
therapeutic
outcomes
due
limitations
such
as
low
bioavailability,
poor
biocompatibility,
nonspecific
targeting,
drug-induced
toxicity,
the
growing
issue
resistance.
Therefore,
concept
a
resistance-proof
agent
(RPAA)
its
smart
delivery
was
introduced
overcome
existing
problem
targeted
specific
properties,
as:
high
biodegradability,
binding
capacity
with
pathogen,
multiple
targeting
delivery,
etc.
This
system
generates
positive
impact
could
quash
multidrug
resistance
problem.
In
this
review,
we
discuss:
rationale
for
developing
nanoengineering-based
smart-delivery
RPAA,
advantageous
properties
system,
possible
mechanism
challenges
in
development
nano-drug
therapeutics
tool
RPAA
solution
combat
global
drug
We
emphasize
urgent
need
next-generation
discuss
opportunities/hurdles
well
questions
that
remain
be
addressed.
article
is
important
because
it
sheds
light
nanoengineered
initiate
new
ways
thinking
about
future-generation
systems.
shares
promising
idea
would
an
essential
foundation
opening
window
field
discovery
RPAA.
Язык: Английский