Research Progress on the Exacerbation of Lipid Metabolism by Malassezia and Its Impact on the Skin Barrier Function

Cosmetics, Journal Year: 2025, Volume and Issue: 12(2), P. 67 - 67

Published: April 3, 2025

The study of the fungal communities skin constitutes a pivotal component microbiome research. Within these communities, genus Malassezia stands out as major constituent, representing 50% to 80% total colonization on healthy individuals. excessive growth or metabolic irregularities this are intimately connected with onset various disorders that intrinsically linked its lipid-dependent nature. Cutaneous lipid metabolism is indispensable for maintaining barrier function and health. possesses ability encode multiple lipase genes, secretion lipases plays role in survival strategies fungi. This review explores recent advances ecological niche microecological homeostasis, mechanism disrupting lipids through catabolic metabolites, relationship between disruption diseases. offers reference future research mechanisms by which affects provides theoretical foundation development innovative therapeutic approaches dermatological conditions.

Language: Английский

Mild Phototherapy Strategies for Preventing Pathogen Infection and Enhancing Cell Proliferation in Diabetic Wound

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 27, 2025

Abstract Excessive inflammation, bacterial infection, and impaired cell proliferation posed significant challenges to diabetic wound healing. There is an urgent need for effective method that can simultaneously provide antibacterial activity promote facilitate the healing of bacteria‐infected wounds. In this study, a novel nanoplatform, GDYO‐VPIM‐Au designed, by co‐decorating 1‐vinyl‐3‐pentylimidazolium bromide ([VPIM]Br) gold nanorods (Au NRs) on graphdiyne oxide (GDYO) nanosheets. exhibited excellent properties against drug‐resistant bacteria through reactive oxygen species (ROS) generation electrostatic interactions. Moreover, with synergistic effect mild phototherapy therapy (mPTT) produced Au NRs efficient significantly accelerate infected This work represented promising therapeutic strategy addressing infections enhancing

Language: Английский

Lactobacillus plantarum in high methoxylated pectin-based encapsulation systems supports gut epithelial wound healing in vitro

Food Hydrocolloids for Health, Journal Year: 2025, Volume and Issue: unknown, P. 100218 - 100218

Published: May 1, 2025

Language: Английский