Lab-on-Skin: A Review of Flexible and Stretchable Electronics for Wearable Health Monitoring

ACS Nano, Год журнала: 2017, Номер 11(10), С. 9614 - 9635

Опубликована: Сен. 13, 2017

Skin is the largest organ of human body, and it offers a diagnostic interface rich with vital biological signals from inner organs, blood vessels, muscles, dermis/epidermis. Soft, flexible, stretchable electronic devices provide novel platform to soft tissues for robotic feedback control, regenerative medicine, continuous health monitoring. Here, we introduce term "lab-on-skin" describe set that have physical properties, such as thickness, thermal mass, elastic modulus, water-vapor permeability, which resemble those skin. These can conformally laminate on epidermis mitigate motion artifacts mismatches in mechanical properties created by conventional, rigid electronics while simultaneously providing accurate, non-invasive, long-term, Recent progress design fabrication sensors more advanced capabilities enhanced reliability suggest an impending translation these research lab clinical environments. Regarding advances, first part this manuscript reviews materials, strategies, powering systems used electronics. Next, paper provides overview applications cardiology, dermatology, electrophysiology, sweat diagnostics, emphasis how may replace conventional tools. The review concludes outlook current challenges opportunities future directions wearable

Язык: Английский

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Electronic Skin: Recent Progress and Future Prospects for Skin‐Attachable Devices for Health Monitoring, Robotics, and Prosthetics

Advanced Materials, Год журнала: 2019, Номер 31(48)

Опубликована: Сен. 19, 2019

Abstract Recent progress in electronic skin or e‐skin research is broadly reviewed, focusing on technologies needed three main applications: skin‐attachable electronics, robotics, and prosthetics. First, since will be exposed to prolonged stresses of various kinds needs conformally adhered irregularly shaped surfaces, materials with intrinsic stretchability self‐healing properties are great importance. Second, tactile sensing capability such as the detection pressure, strain, slip, force vector, temperature important for health monitoring attachable devices, enable object manipulation surrounding environment robotics For chemical electrophysiological wireless signal communication high significance fully gauge state users ensure user comfort. prosthetics, large‐area integration 3D surfaces a facile scalable manner critical. Furthermore, new processing strategies using neuromorphic devices efficiently process information parallel low power manner. neural interfacing electrodes These topics discussed, progress, current challenges, future prospects.

Язык: Английский

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Advanced Carbon for Flexible and Wearable Electronics

Advanced Materials, Год журнала: 2018, Номер 31(9)

Опубликована: Окт. 9, 2018

Abstract Flexible and wearable electronics are attracting wide attention due to their potential applications in human health monitoring care systems. Carbon materials have combined superiorities such as good electrical conductivity, intrinsic structural flexibility, light weight, high chemical thermal stability, ease of functionalization, well mass production, enabling them be promising candidate for flexible electronics. Consequently, great efforts devoted the controlled fabrication carbon with rationally designed structures next‐generation Herein, latest advances rational design toward reviewed. Various (carbon nanotubes, graphene, natural‐biomaterial‐derived carbon, etc.) micro/nanostructures macroscopic morphologies high‐performance introduced. The strategies, working mechanism, performance, carbon‐based devices reviewed discussed, including strain/pressure sensors, temperature/humidity electrochemical conductive electrodes/wires, power devices. Furthermore, integration multiple multifunctional systems is briefly Finally, existing challenges future opportunities this field summarized.

Язык: Английский

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Wearable and flexible electronics for continuous molecular monitoring

Chemical Society Reviews, Год журнала: 2018, Номер 48(6), С. 1465 - 1491

Опубликована: Апрель 3, 2018

Wearable/flexible chemical sensors enable continuous molecular monitoring and provide an individual's dynamic health information at the level.

Язык: Английский

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A New Frontier of Printed Electronics: Flexible Hybrid Electronics

Advanced Materials, Год журнала: 2019, Номер 32(15)

Опубликована: Ноя. 19, 2019

Abstract The performance and integration density of silicon integrated circuits (ICs) have progressed at an unprecedented pace in the past 60 years. While ICs thrive low‐power high‐performance computing, creating flexible large‐area electronics using remains a challenge. On other hand, printed use intrinsically materials printing techniques to manufacture compliant electronics. Nonetheless, are not as efficient for computation signal communication. Flexible hybrid (FHE) leverages strengths these two dissimilar technologies. It uses where flexibility scalability required, i.e., sensing actuating, communication purposes. Combining yields very powerful versatile technology with vast range applications. Here, fundamental building blocks FHE system, sensors circuits, thinned ICs, antennas, energy harvesting storage modules, displays, discussed. Emerging application areas wearable health, structural industrial, environmental, agricultural reviewed. Overall, recent progress, fabrication, application, challenges, outlook, related presented.

Язык: Английский

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Wearable Chemical Sensors: Present Challenges and Future Prospects

ACS Sensors, Год журнала: 2016, Номер 1(5), С. 464 - 482

Опубликована: Май 6, 2016

Wearable sensors have received considerable interest over the past decade owing to their tremendous promise for monitoring wearers' health, fitness, and surroundings. However, only limited attention has been directed at developing wearable chemical that offer more comprehensive information about a wearer's well-being. The development of faces multiple challenges on various fronts. This perspective reviews key technological gaps impeding successful realization effective sensor systems, related materials, power, analytical procedure, communication, data acquisition, processing, security. Size, rigidity, operational requirements present are incompatible with technology. Sensor stability on-body surface regeneration constitute challenges. Similarly, power sources incapable meeting electronics low energy densities slow recharging. Several energy-harvesting methodologies inherent issues, including inconsistent supply stability. There also major pertaining handling securing big generated by sensors. These include achieving high transfer rates efficient mining. Efforts must be made toward next generation cryptologic algorithms ensuring security user privacy. facing field sensors, in general, can thus addressed multidisciplinary approach where researchers from diverse fields work unison. article discusses these potential solutions along future prospects.

Язык: Английский

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Recent advances in wearable tactile sensors: Materials, sensing mechanisms, and device performance

Materials Science and Engineering R Reports, Год журнала: 2017, Номер 115, С. 1 - 37

Опубликована: Март 6, 2017

Язык: Английский

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Enzyme‐Based Glucose Sensor: From Invasive to Wearable Device

Advanced Healthcare Materials, Год журнала: 2018, Номер 7(8)

Опубликована: Янв. 15, 2018

Abstract Blood glucose concentration is a key indicator of patients' health, particularly for symptoms associated with diabetes mellitus. Because the large number diabetic patients, many approaches measurement have been studied to enable continuous and accurate level monitoring. Among them, electrochemical analysis prominent because it simple quantitative. This technology has incorporated into commercialized research‐level devices from test strips wearable implantable systems. Although directly monitoring blood assures information, invasive needle‐pinching step collect often results in patients (particularly young patients) being reluctant adopt process. An sensor may avoid burden repeated collections, but quite requires periodic replacement owing biofouling its short lifetime. Therefore, noninvasive methods estimate levels tears, saliva, interstitial fluid (ISF), sweat are currently studied. review discusses evolution enzyme‐based sensors, including materials, device structures, fabrication processes, system engineering. Furthermore, using various biofluids or described, highlighting recent progress development sensors their integrated

Язык: Английский

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A Mussel‐Inspired Conductive, Self‐Adhesive, and Self‐Healable Tough Hydrogel as Cell Stimulators and Implantable Bioelectronics

Small, Год журнала: 2016, Номер 13(2)

Опубликована: Окт. 25, 2016

A graphene oxide conductive hydrogel is reported that simultaneously possesses high toughness, self-healability, and self-adhesiveness. Inspired by the adhesion behaviors of mussels, our shows self-adhesiveness on various surfaces soft tissues. The can be used as self-adhesive bioelectronics, such electrical stimulators to regulate cell activity implantable electrodes for recording in vivo signals. As a service authors readers, this journal provides supporting information supplied authors. Such materials are peer reviewed may re-organized online delivery, but not copy-edited or typeset. Technical support issues arising from (other than missing files) should addressed Please note: publisher responsible content functionality any Any queries content) directed corresponding author article.

Язык: Английский

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An Overview of the Development of Flexible Sensors

Advanced Materials, Год журнала: 2017, Номер 29(33)

Опубликована: Июль 3, 2017

Flexible sensors that efficiently detect various stimuli relevant to specific environmental or biological species have been extensively studied due their great potential for the Internet of Things and wearable electronics applications. The application flexible stretchable device-engineering technologies has enabled fabrication slender, lightweight, stretchable, foldable sensors. Here, recent studies on analytes, ions, light, pH are outlined. In addition, contemporary device structure, materials, methods discussed, a market overview is provided. conclusion presents challenges perspectives in this field.

Язык: Английский

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