Nature Communications,
Год журнала:
2022,
Номер
13(1)
Опубликована: Июнь 17, 2022
Clusteroluminogens
refer
to
some
non-conjugated
molecules
that
show
visible
light
and
unique
electronic
properties
with
through-space
interactions
due
the
formation
of
aggregates.
Although
mature
systematic
theories
molecular
photophysics
have
been
developed
study
conventional
conjugated
chromophores,
it
is
still
challenging
endow
clusteroluminogens
designed
photophysical
by
manipulating
interactions.
Herein,
three
donor-acceptor
structures
different
halide
substituents
are
synthesized.
These
compounds
multiple
emissions
even
single-molecule
white-light
emission
in
crystalline
state.
The
intensity
ratio
these
easily
manipulated
changing
atom
excitation
wavelength.
Experimental
theoretical
results
successfully
disclose
nature
emissions:
conjugation
for
short-wavelength
fluorescence,
charge
transfer
based
on
secondary
long-wavelength
room-temperature
phosphorescence.
introduction
not
only
enriches
their
varieties
but
also
inspires
establishment
novel
aggregate
clusteroluminescence.
Angewandte Chemie International Edition,
Год журнала:
2020,
Номер
59(25), С. 9868 - 9886
Опубликована: Март 4, 2020
Abstract
The
concept
of
aggregation‐induced
emission
(AIE)
has
opened
new
opportunities
in
many
research
fields.
Motivated
by
the
unique
feature
AIE
fluorogens
(AIEgens),
during
past
decade,
molecular
probes
and
nanoparticle
(NP)
have
been
developed
for
sensing,
imaging
theranostic
applications
with
excellent
performance
outperforming
conventional
fluorescent
probes.
This
Review
summarizes
latest
advancement
NP
their
emerging
biomedical
applications.
Special
focus
is
to
reveal
how
are
evolved
development
multifunctional
AIEgens,
strategies
overcome
limitations
traditional
more
translational
via
fluorescence
imaging,
photoacoustic
image‐guided
photodynamic/photothermal
therapy.
outlook
discusses
challenges
future
AIEgens
advance
field.
Chemical Society Reviews,
Год журнала:
2020,
Номер
49(22), С. 8179 - 8234
Опубликована: Янв. 1, 2020
Phototheranostics
represents
a
promising
direction
for
modern
precision
medicine,
which
has
recently
attracted
great
research
interest
from
multidisciplinary
areas.
Organic
optical
agents
including
small
molecular
fluorophores,
semiconducting/conjugated
polymers,
aggregation-induced
emission
luminogens,
etc.
with
tuneable
photophysical
properties,
high
biosafety
and
biocompatibility,
facile
processability
ease
of
functionalization
have
delivered
encouraging
performance
in
disease
phototheranostics.
This
review
summarizes
the
recent
progress
organic
phototheranostic
an
emphasis
on
main
strategies
to
manipulate
three
excitation
energy
dissipation
pathways,
namely,
radiative
decay,
thermal
deactivation,
intersystem
crossing,
assistance
Jablonski
diagram,
particularly
showcases
how
diagram
been
guiding
design
molecule
aggregate
levels
promote
outcomes.
Molecular
nanoengineering
modulate
processes
convert
absorbed
photons
into
fluorescent/phosphorescent/photoacoustic
signals
and/or
photodynamic/photothermal
curing
effects
improved
phototheranostics
are
elaborated.
Noteworthily,
adaptive
activatable
transformable
functions
demand,
regulation
such
as
chemiexcitation
efficacies
also
included.
A
brief
summary
discussion
current
challenges
future
perspectives
this
field
is
further
presented.
Aggregate,
Год журнала:
2020,
Номер
1(1), С. 80 - 106
Опубликована: Дек. 1, 2020
Abstract
Theranostics
referring
to
the
ingenious
integration
of
diagnostics
and
therapeutics
has
garnered
tremendous
attention
in
these
years
as
it
provides
a
promising
opportunity
for
modern
personalized
precision
medicine.
By
virtue
good
biocompatibility,
outstanding
fluorescence
property,
easy
processability
functionalization,
promoted
photosensitizing
efficiency,
well
facile
construction
multi‐modality
theranostics,
fluorophores
with
aggregation‐induced
emission
(AIE)
characteristics
exhibit
inexhaustible
vigorous
vitality
field
theranostics.
Numerous
significant
breakthroughs
state‐of‐the‐art
progression
have
been
witnessed
past
few
years.
This
review
highlights
aggregation‐enhanced
superiorities
AIE
luminogens
(AIEgens)
disease
theranostics
mainly
involving
diagnostic
imaging
(fluorescence
room
temperature
phosphorescence),
therapeutic
intervention
(photodynamic
therapy),
feasibility
based
on
experimental
measurements
theoretical
simulations.
Additionally,
latest
advanced
developments
AIEgens
aspect
corresponding
strategies
design
highly
effective
AIE‐active
through
triggering
aggregation
formation
are
comprehensively
summarized.
Moreover,
brief
conclusion
discussion
current
challenges
future
perspectives
this
area
is
further
presented.
Advanced Materials,
Год журнала:
2020,
Номер
32(36)
Опубликована: Июль 30, 2020
Abstract
Molecular
science
entails
the
study
of
structures
and
properties
materials
at
level
single
molecules
or
small
interacting
complexes
molecules.
Moving
beyond
well‐defined
complexes,
aggregates
(i.e.,
irregular
clusters
many
molecules)
serve
as
a
particularly
useful
form
that
often
display
modified
wholly
new
compared
to
their
molecular
components.
Some
unique
phenomena
such
polymorphic
aggregates,
aggregation‐induced
symmetry
breaking,
cluster
excitons
are
only
identified
in
few
examples
exotic
features.
Here,
by
virtue
flourishing
research
on
emission,
concept
“aggregate
science”
is
put
forward
fill
gaps
between
aggregates.
Structures
aggregate
scale
also
systematically
summarized.
The
structure–property
relationships
established
for
expected
contribute
technological
development.
Ultimately,
may
become
an
interdisciplinary
field
serves
general
platform
academic
research.
Aggregate,
Год журнала:
2020,
Номер
1(1), С. 6 - 18
Опубликована: Дек. 1, 2020
Abstract
The
research
of
organic
luminescent
materials
in
aggregate
has
drawn
more
and
attention
for
their
wide
applications.
To
adjust
the
properties
aggregates,
a
deep
understanding
corresponding
internal
mechanism
is
needed.
In
this
short
review,
brief
introduction
aggregation‐induced
emission
(AIE)
some
other
solid
state
luminescence
behaviors
derived
from
or
parallel
to
AIE
presented.
Particularly,
relationship
between
property
intermolecular/intramolecular
interactions
summarized,
with
aim
guide
further
development
optoelectronic
aggregate.
Advanced Materials,
Год журнала:
2021,
Номер
33(32)
Опубликована: Июнь 17, 2021
Abstract
The
unique
advantages
and
the
exciting
application
prospects
of
AIEgens
have
triggered
booming
developments
in
this
area
recent
years.
Among
them,
stimuli‐responsive
received
particular
attention
impressive
progress,
they
been
demonstrated
to
show
tremendous
potential
many
fields
from
physical
chemistry
materials
science
biology
medicine.
Here,
achievements
terms
seven
most
representative
types
stimuli
including
force,
light,
polarity,
temperature,
electricity,
ion,
pH,
are
summarized.
Based
on
typical
examples,
it
is
illustrated
how
each
type
systems
realize
desired
performance
for
various
applications.
key
work
principles
behind
them
ultimately
deciphered
figured
out
offer
new
insights
guidelines
design
engineering
next‐generation
luminescent
more
broad
Chemical Society Reviews,
Год журнала:
2022,
Номер
51(6), С. 1983 - 2030
Опубликована: Янв. 1, 2022
This
review
summarized
the
progression
of
AIEgen-based
photo-driven
theranostics
emphasizing
on
design
strategies
for
efficient
photosensitization,
photothermal
conversion
and
multimodal
functionalities
by
adjusting
excited
energy
dissipation.
Angewandte Chemie International Edition,
Год журнала:
2021,
Номер
60(27), С. 14945 - 14953
Опубликована: Апрель 22, 2021
Maximization
of
phototoxic
damage
on
tumor
with
minimized
side
effect
normal
tissue
is
essential
for
effective
anticancer
photodynamic
therapy
(PDT).
This
requires
highly
cancer-cell-specific
or
even
cancer-cell-organelle-specific
synthesis
delivery
efficient
photosensitizers
(PSs)
in
vitro
and
vivo,
which
difficult
to
achieve.
Herein,
we
report
a
strategy
cancer-cell-activated
PS
synthesis,
by
an
mitochondria-targeting
photosensitizer
aggregation-induced-emission
(AIE)
feature
can
be
selectively
synthesized
as
image-guided
PDT
agent
inside
cancer
cells.
MOF-199,
CuII
-based
metal-organic
framework,
was
selected
inert
carrier
load
the
precursors
served
CuI
catalyst
source
situ
click
reaction
form
PSs
exclusively
The
showed
capability,
allowing
potent
ablation
under
light
irradiation.
high
specificity
produced
cells
also
makes
it
safer
post-treatment.
JACS Au,
Год журнала:
2021,
Номер
1(11), С. 1805 - 1814
Опубликована: Сен. 30, 2021
Conventional
π-conjugated
luminophores
suffer
from
problems
such
as
emission
quenching,
biotoxicity,
environmental
pollution,
etc.
The
emerging
nonconjugated
and
nonaromatic
clusteroluminogens
(CLgens)
are
expected
to
overcome
these
stubborn
drawbacks,
so
research
of
CLgens
shows
great
significance
not
only
for
practical
application
but
also
the
construction
fundamental
photophysical
theories.
This
perspective
summarizes
unusual
features
in
comparison
traditional
chromophores,
molecular
structures,
unmatched
absorption
excitation,
excitation-dependent
luminescence,
multiple
peaks,
room-temperature
phosphorescence.
Different
theory
through-bond
conjugation
luminophores,
through-space
interactions,
including
n···n
interaction
n···π
interaction,
regarded
emitting
sources
CLgens.
In
addition,
formation
network
clusters
is
proposed
an
efficient
strategy
improve
performance
CLgens,
their
potential
applications
anticounterfeiting,
photoelectronic
devices,
bioimaging
prospected.
Journal of the American Chemical Society,
Год журнала:
2022,
Номер
144(13), С. 6107 - 6117
Опубликована: Март 22, 2022
Long-lived
organic
room-temperature
phosphorescence
(RTP)
has
sparked
intense
explorations,
owing
to
the
outstanding
optical
performance
and
exceptional
applications.
Because
triplet
excitons
in
RTP
experience
multifarious
relaxation
processes
resulting
from
their
high
sensitivity,
spin
multiplicity,
inevitable
nonradiative
decay,
external
quenchers,
boosting
by
modulated
triplet-exciton
behavior
is
challenging.
Herein,
we
report
that
cross-linked
polyphosphazene
nanospheres
can
effectively
promote
long-lived
RTP.
Through
molecular
engineering,
multiple
carbonyl
groups
(C═O),
heteroatoms
(N
P),
heavy
atoms
(Cl)
are
introduced
into
nanospheres,
largely
strengthening
spin-orbit
coupling
constant
recalibrating
electronic
configurations
between
singlet
(Sn)
(Tn)
excitons.
In
order
further
suppress
decay
avoid
quenching
under
ambient
conditions,
encapsulated
with
poly(vinyl
alcohol)
matrix,
thus
synchronously
prompting
lifetime
(173
ms
longer),
efficiency
(∼12-fold
higher),
afterglow
duration
time
(more
than
20
s),
absolute
luminance
(∼19-fold
higher)
as
compared
2,3,6,7,10,11-hexahydroxytriphenylene
precursor.
By
measuring
emission
intensity
of
phosphorescence,
an
effective
probe
based
on
developed
for
visible,
quantitative,
expeditious
detection
volatile
compounds.
More
significantly,
obtained
films
show
selectivity
robustness
anisole
(7.1
×
10-4
mol
L-1).
This
work
not
only
demonstrates
a
way
toward
materials
but
also
provides
new
avenue
apply
feasible
