Advanced Functional Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 12, 2024
Abstract
Freeze
casting
is
a
solidification
technique
utilized
in
the
fabrication
of
porous
materials.
However,
freeze
process
quite
complex,
and
significant
challenges
remain
precisely
controlling
pore
size
shape
structures.
This
study
aims
to
investigate
customization
multifunctional
electromagnetic
wave
(EMW)
absorbers
with
3D
structures
via
casting.
review
initially
presents
fundamental
principles
underlying
examines
correlation
between
internal
external
factors
during
preparation
porosity.
The
emerging
trends
constructing
novel
intricate
macroscopic
through
are
subsequently
outlined.
Furthermore,
this
focuses
on
composites
various
microstructures
low‐dimensional
building
blocks,
their
EMW
response
properties.
By
regulating
influencing
mechanisms
casting,
absorption
materials
exhibit
outstanding
advantages
such
as
property
manipulation,
controllable
structure,
high
porosity,
specific
surface
area,
lightweight,
flexibility.
These
features
broaden
applications
shielding,
mechanical
property,
radar
stealth,
thermal
insulation
fire
prevention,
flexible
sensors,
antifreeze
ability,
etc.
In
addition,
we
discuss
prospects
high‐performance
using
techniques.
Advanced Materials,
Год журнала:
2021,
Номер
34(12)
Опубликована: Дек. 22, 2021
Due
to
the
poor
mechanical
properties
of
many
hydrogel
bioinks,
conventional
3D
extrusion
bioprinting
is
usually
conducted
based
on
X-Y
plane,
where
deposited
layers
are
stacked
in
Z-direction
with
or
without
support
prior
layers.
Herein,
a
technique
reported,
taking
advantage
cryoprotective
bioink
enable
direct
vertical
direction
presence
cells,
using
freezing
plate
precise
temperature
control.
Of
interest,
cryo-bioprinting
concurrently
allows
user
create
freestanding
filamentous
constructs
containing
interconnected,
anisotropic
microchannels
featuring
gradient
sizes
aligned
direction,
also
associated
enhanced
performances.
Skeletal
myoblasts
within
3D-cryo-bioprinted
show
cell
viability,
spreading,
and
alignment,
compared
same
cells
standard
constructs.
This
method
further
extended
multimaterial
format,
finding
potential
applications
interface
tissue
engineering,
such
as
creation
muscle-tendon
unit
muscle-microvascular
unit.
The
unique
presented
here
suggests
improvements
robustness
versatility
engineer
certain
types
especially
those
nature,
may
extend
broad
utilities
regenerative
medicine,
drug
discovery,
personalized
therapeutics.
Gels,
Год журнала:
2022,
Номер
8(10), С. 606 - 606
Опубликована: Сен. 21, 2022
Hydrogels
have
been
extensively
used
as
scaffolds
in
tissue
engineering
for
cell
adhesion,
proliferation,
migration,
and
differentiation
because
of
their
high-water
content
biocompatibility
similarity
to
the
extracellular
matrix.
However,
submicron
or
nanosized
pore
networks
within
hydrogels
severely
limit
survival
regeneration.
In
recent
years,
application
macroporous
has
received
considerable
attention.
The
structure
not
only
facilitates
nutrient
transportation
metabolite
discharge
but
also
provides
more
space
behavior
formation.
Several
strategies
creating
functionalizing
reported.
This
review
began
with
an
overview
advantages
challenges
regulation
cellular
behavior.
addition,
advanced
methods
preparation
modulate
were
discussed.
Finally,
future
research
related
fields
was
Accounts of Materials Research,
Год журнала:
2022,
Номер
4(2), С. 101 - 114
Опубликована: Ноя. 30, 2022
ConspectusHydrogels
are
high-water-content
soft
materials
with
widely
tunable
physicochemical
properties,
resembling
tissues.
Tremendous
progress
in
engineering
hydrogels
good
biocompatibility,
suitable
bioactivities,
and
controlled
geometries
has
made
them
promising
candidates
for
broad
applications.
Nevertheless,
conventional
usually
suffer
from
weak
mechanical
limiting
their
use
biomedical
settings
involving
load-bearing
persistent
deformations.
Inspired
by
the
extreme
properties
multiscale
hierarchical
structures
of
biological
tissues,
mechanically
robust
tough
have
been
developed.
Combining
other
desired
performance
characteristics
functional
expands
opportunities
fields.
This
Account
seeks
to
guide
readership
regarding
recent
a
focus
on
molecular/structural
design
novel
fabrications,
particularly
surrounding
works
reported
our
groups.
Meanwhile,
multiple
applications
discussed,
highlighting
underlying
mechanisms
governing
relevant
We
begin
introducing
definition,
measurements,
principles
hydrogel
adhesives
terms
mechanics.
Various
molecular
structural
approaches
building
dissipation
into
stretchable
realize
stress
homogenization
or
energy
exploited
fabricate
hydrogels.
Molecular
engineering-based
network
architecture
homogeneous
heterogeneous
elaborated.
The
energy-dissipation-based
reinforced
sacrificial
bonds
components,
leading
substantial
toughness
reduction
subsequent
loading
cycles.
To
this
end,
new
designs,
including
highly
entangled
sliding-ring
hydrogels,
developed
resolve
toughness–hysteresis
conflict.
In
addition,
processing
techniques,
salting
out,
freeze
casting,
three-dimensional
(bio)printing,
manipulate
fabrication.
As
some
most
actively
studied
years,
finding
as
bioadhesives/coatings,
tissue-engineering
scaffolds,
robot/actuators,
bioelectronics
interfaces.
development
bioadhesives/coatings
lies
constructing
strong
interfacial
linkages
between
substrates,
having
wound
closure
drug
delivery.
Tough
also
tissue
regenerative
medicine,
although
conflict
robustness–cellular
function
restricts
practical
flexible
compliant
stimuli-responsive
shape
shifting
pressure-triggered
actuation
make
actuators
robots
devices
dealing
Conductive
utility
bioelectronics.
we
highlight
major
challenges
emphasize
trends
developing
next-generation
medical
Proceedings of the National Academy of Sciences,
Год журнала:
2022,
Номер
119(44)
Опубликована: Окт. 24, 2022
Organoid
technology
has
provided
unique
insights
into
human
organ
development,
function,
and
diseases.
Patient-derived
organoids
are
increasingly
used
for
drug
screening,
modeling
rare
disorders,
designing
regenerative
therapies,
understanding
disease
pathogenesis.
However,
the
use
of
Matrigel
to
grow
represents
a
major
challenge
in
clinical
translation
organoid
technology.
is
poorly
defined
mixture
extracellular
matrix
proteins
growth
factors
extracted
from
Engelbreth–Holm–Swarm
mouse
tumor.
The
driver
multiple
cellular
processes
differs
significantly
between
tissues
as
well
healthy
states
same
tissue.
Therefore,
we
envisioned
that
derived
native
tissue
would
be
able
support
akin
organogenesis
vivo.
Here,
have
developed
hydrogels
decellularized
bovine
endometrium.
These
supported
endometrial
organoids,
which
was
comparable
Matrigel.
Organoids
grown
were
proteomically
more
similar
than
those
cultured
Proteomic
Raman
microspectroscopy
analyses
showed
method
decellularization
affects
biochemical
composition
and,
subsequently,
their
ability
growth.
amount
laminin
correlated
with
number
shape
organoids.
We
also
demonstrated
utility
developing
solid
scaffolds
supporting
high-throughput,
cell
culture–based
applications.
In
summary,
overcome
limitation
greatly
expand
applicability
understand
biology
associated
pathologies.
