Advanced Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 9, 2024
All-aqueous
embedded
3D
printing,
which
involves
extruding
inks
in
an
aqueous
bath,
has
emerged
as
a
transformative
platform
for
the
freeform
fabrication
of
constructs
with
precise
control.
The
use
supporting
bath
not
only
enables
printing
arbitrarily
designed
but
also
broadens
ink
selection
various
soft
matters,
advancing
wide
application
this
technology.
This
review
focuses
on
recent
progress
preparation
using
all-aqueous
printing.
It
begins
by
discussing
significance
ultralow
interfacial
tension
all-liquid
and
highlights
fundamental
concepts
properties
system.
then
introduces
advances
clarifies
key
factors
affecting
stability
shape
fidelity,
aiming
to
guide
expansion
assessment
emerging
systems
used
representative
applications.
Furthermore,
it
proposes
potential
scope
applications
technology,
including
vitro
models,
cytomimetic
microreactors,
ionic
electronics.
Finally,
discusses
challenges
facing
current
offers
future
perspectives
possible
improvements
developments.
Chemical Reviews,
Год журнала:
2024,
Номер
124(14), С. 8787 - 8822
Опубликована: Июль 5, 2024
Harnessing
light
for
cross-linking
of
photoresponsive
materials
has
revolutionized
the
field
3D
printing.
A
wide
variety
techniques
leveraging
broad-spectrum
shaping
have
been
introduced
as
a
way
to
achieve
fast
and
high-resolution
printing,
with
applications
ranging
from
simple
prototypes
biomimetic
engineered
tissues
regenerative
medicine.
Conventional
light-based
printing
use
material
in
layer-by-layer
fashion
produce
complex
parts.
Only
recently,
new
emerged
which
deploy
multidirection,
tomographic,
light-sheet
or
filamented
image
projections
deep
into
volume
resin-filled
vat
photoinitiation
cross-linking.
These
Deep
Vat
(DVP)
approaches
alleviate
need
layer-wise
enable
unprecedented
fabrication
speeds
(within
few
seconds)
high
resolution
(>10
μm).
Here,
we
elucidate
physics
chemistry
these
processes,
their
commonalities
differences,
well
emerging
biomedical
non-biomedical
fields.
Importantly,
highlight
limitations,
future
scope
research
that
will
improve
scalability
applicability
DVP
engineering
medicine
applications.
Materials Today Bio,
Год журнала:
2024,
Номер
28, С. 101185 - 101185
Опубликована: Авг. 5, 2024
3D
bioprinting
technologies
and
bioink
development
are
enabling
significant
advances
in
miniaturized
integrated
biosensors.
For
example,
bioreceptors
can
be
immobilized
within
a
porous
structure
to
significantly
amplify
the
signal,
while
biocompatible
mechanically
flexible
systems
uniquely
enable
wearable
chem-
bio-sensors.
This
advancement
is
accelerating
translation
by
production
of
high
performance,
reproducible,
analytical
devices.
The
formulation
plays
crucial
role
determining
bio-functionality
resulting
printed
structures,
e.g.,
porosity
that
allows
analyte
diffuse
through
structure,
affinity
avidity
receptors,
etc.
review
explores
next
generation
advanced
bioinks
for
biosensor
provides
insights
into
latest
cutting-edge
technologies.
methods
available
fabrication
including
inkjet,
extrusion,
laser-based
bioprinting,
discussed.
advantages
limitations
each
method
analysed,
recent
advancements
presented.
then
delves
properties
bioinks,
such
as
biocompatibility,
printability,
stability,
applicability.
Different
types
explored,
multicomponent,
stimuli-responsive,
conductive
bioinks.
Finally,
biosensors
considered,
identifying
possible
new
opportunities
challenges.
Overall,
this
literature
highlights
combined
importance
high-performance
Trends in biotechnology,
Год журнала:
2024,
Номер
42(10), С. 1241 - 1257
Опубликована: Апрель 23, 2024
Advances
in
tissue
engineering
for
both
system
modeling
and
organ
regeneration
depend
on
embracing
recapitulating
the
target
tissue's
functional
structural
complexity.
Microenvironmental
features
such
as
anisotropy,
heterogeneity,
other
biochemical
mechanical
spatiotemporal
cues
are
essential
regulating
development
function.
Novel
biofabrication
strategies
innovative
biomaterial
design
have
emerged
promising
tools
to
better
reproduce
features.
These
facilitate
a
transition
towards
high-fidelity
biomimetic
structures,
offering
opportunities
deeper
understanding
of
function
superior
therapies.
In
this
review,
we
explore
some
key
compositional
aspects
tissues,
lay
out
how
achieve
similar
outcomes
with
current
fabrication
strategies,
identify
main
challenges
avenues
future
research.
Additive
manufacturing
(AM)
of
ceramics
has
significantly
contributed
to
advancements
in
ceramic
fabrication,
solving
some
the
difficulties
conventional
processing
and
providing
additional
possibilities
for
structure
function
components.
However,
defects
induced
by
layer-by-layer
approach
on
which
traditional
AM
techniques
are
based
still
constitute
a
challenge
address.
This
study
presents
volumetric
SiOC
from
preceramic
polymer
using
xolography,
linear
process
that
allows
avoid
staircase
effect
typical
other
vat
photopolymerization
techniques.
Besides
optimizing
trade-off
between
content
transmittance,
pore
generator
is
introduced
create
transient
channels
gas
release
before
decomposition
organic
constituents
moieties,
resulting
crack-free
solid
structures
even
at
low
yield.
Formulation
optimization
alleviated
sinking
printed
parts
during
printing
prevented
shape
distortion.
Complex
porous
with
smooth
surface
sharp
features
fabricated
under
optimized
parameters.
work
provides
new
method
µm/mm
scale
high
quality
large
geometry
variety
an
efficient
way,
opening
possibility
applications
fields
such
as
micromechanical
systems
microelectronic
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 26, 2025
Abstract
Volumetric
Bioprinting
(VBP),
enables
to
rapidly
build
complex,
cell‐laden
hydrogel
constructs
for
tissue
engineering
and
regenerative
medicine.
Light‐based
tomographic
manufacturing
spatial‐selective
polymerization
of
a
bioresin,
resulting
in
higher
throughput
resolution
than
what
is
achieved
using
traditional
techniques.
However,
methods
multi‐material
printing
are
needed
broad
VBP
adoption
applicability.
Although
converging
with
extrusion
bioprinting
support
baths
offers
novel,
promising
solution,
further
knowledge
on
the
hydrogels
as
light‐responsive,
volumetrically
printable
needed.
Therefore,
this
study
investigates
tuning
gelatin
macromers,
particular
leveraging
effect
molecular
weight
degree
modification,
overcome
these
challenges,
creating
library
materials
Embedded
Printing
(EmVP).
Bioresins
tunable
printability
mechanical
properties
produced,
novel
subset
gelatins
GelMA
exhibiting
stable
shear‐yielding
behavior
new,
single‐component,
ready‐to‐use
suspension
medium
in‐bath
printing,
which
over
multiple
hours
without
needing
temperature
control.
As
proof‐of‐concept
biological
application,
bioprinted
gels
tested
insulin‐producing
pancreatic
cell
lines
21
days
culture.
Leveraging
multi‐color
printer,
complex
multi‐cellular
geometries
enhancing
accessibility
volumetric
advanced
models.