International Journal of Hydrogen Energy, Год журнала: 2024, Номер 98, С. 1464 - 1477
Опубликована: Дек. 18, 2024
Язык: Английский
International Journal of Hydrogen Energy, Год журнала: 2024, Номер 98, С. 1464 - 1477
Опубликована: Дек. 18, 2024
Язык: Английский
Angewandte Chemie International Edition, Год журнала: 2024, Номер 63(44)
Опубликована: Авг. 7, 2024
Abstract Self‐protective carbonized polymer dots (CPDs) with advantageous crosslinked nano‐structures have attracted considerable attention in metal‐free room temperature phosphorescence (RTP) materials, whereas their RTP emissions are still limited to short wavelength. Expanding Near‐Infrared (NIR) range is attractive but suffers from the difficulties constructing narrow energy levels and inhibiting intense non‐radiative decay. Herein, a crosslink‐enhanced emission (CEE)‐dominated construction strategy was proposed, achieving desired NIR (710 nm) self‐protective CPDs for first time. Structural factors, i.e., crosslinking (covalent‐bond CEE), conjugation (conjugated amine bridging N−H C=C group), steric hindrance (confined‐domain were confirmed indispensable triggering CPDs. Contrast experiments theoretical calculations further revealed rationality of design originating CEE terms promoting level triplet excitons quenching. This work not only firstly achieves also helps understand origin guide synthesis diverse efficient long‐wavelength emission.
Язык: Английский
Процитировано
11Diamond and Related Materials, Год журнала: 2024, Номер 146, С. 111259 - 111259
Опубликована: Июнь 1, 2024
Язык: Английский
Процитировано
3Small, Год журнала: 2025, Номер 21(9)
Опубликована: Янв. 19, 2025
Abstract Rare genetic diseases (RGDs) affect a small percentage of the global population but collectively have substantial impact due to their diverse manifestations. Although precise reasons behind these remain unclear, roughly 80% cases are genetically linked. Recent efforts focus on understanding pathology and developing new diagnostic therapeutic approaches for RGDs. However, there persists gap between fundamental research clinical approaches, where advancements in nanotechnology offer promising improvements. In this context, nanosized light‐emitting quantum dots (QDs), ranging from 2–10 nm, materials applications. Their size‐tunable light emission, high yield, photostability allow tracking cargo. Additionally, QDs can be functionalized with agents, antibodies, or peptides target specific cellular pathways, enhancing treatment efficacy while minimizing side effects. By combining capabilities single platform, thus versatile powerful approach tackle rare disorders. Despite several reviews various applications QDs, utilization domain RGDs is not well documented. This review highlight QDs’ potential diagnosing treating certain addresses challenges limiting application.
Язык: Английский
Процитировано
0Bioactive Materials, Год журнала: 2025, Номер 49, С. 291 - 339
Опубликована: Март 13, 2025
Язык: Английский
Процитировано
0Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113392 - 113392
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0Research Square (Research Square), Год журнала: 2025, Номер unknown
Опубликована: Апрель 7, 2025
Язык: Английский
Процитировано
0Chemical Engineering Journal, Год журнала: 2025, Номер 512, С. 162712 - 162712
Опубликована: Апрель 16, 2025
Язык: Английский
Процитировано
0FlatChem, Год журнала: 2024, Номер 47, С. 100735 - 100735
Опубликована: Сен. 1, 2024
Язык: Английский
Процитировано
2Microchemical Journal, Год журнала: 2024, Номер unknown, С. 112046 - 112046
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
2Advanced Functional Materials, Год журнала: 2024, Номер unknown
Опубликована: Дек. 4, 2024
Abstract Phototoxicity poses a substantial challenge in photodynamic therapy, resulting intolerable skin damage, visual impairment, and reduced quality of life. Current coping strategies, primarily focus on avoiding inappropriate photoactivation developing targeted photosensitizers, have not effectively addressed this problem. Hence, study aims to develop “sunlight‐friendly” therapy strategy. Here, 1‐methoxyphenazine methosulfate (MPMS) is innovatively identified as key substance achieving modified oxygen metabolism. MPMS demonstrates efficient catalytic shuttling under abnormal intracellular H 2 O levels, introducing novel protective approach for metabolism numerous life processes. By controlling administration, the switch photosensitizer states between “ON” (killing tumor cells) “OFF” (safeguarding normal can be achieved. This mitigated phototoxicity holds potential widespread clinical application.
Язык: Английский
Процитировано
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