Advanced Materials Technologies,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 18, 2024
Abstract
Hydrogels
with
programmable
shape
memory
hold
great
promise
for
applications
in
soft
robots,
smart
medical
devices,
etc.,
but
the
preparation
of
tough
and
fast‐responding
hydrogels
remains
challenging.
In
this
work,
Poly
(acrylic
acid
‐N‐isopropyl
acrylamide)
(3:1)‐Fe
3+
(P(AA‐NIPAM)(3:1)‐Fe
)
are
obtained
by
monomer
copolymerization
ionic
coordination,
which
exhibited
mechanical
properties
a
maximum
tensile
strength
2.48
±
0.08
MPa
elongation
338.5
19.6%.
The
hydrogel
also
demonstrated
good
effect,
curled
into
spiral
recovering
to
71.1%
5.9%
30
s
under
swelling
effect
water,
convoluted
structure
95%
4
s.
prepared
based
on
method
will
provide
an
important
reference
value
development
higher
performance
hydrogels.
This
review
summarizes
the
fundamental
concepts,
recent
advancements,
and
emerging
trends
in
field
of
stimuli-responsive
hydrogels.
While
numerous
reviews
exist
on
this
topic,
continues
to
evolve
dynamically,
certain
research
directions
are
often
overlooked.
To
address
this,
we
classify
hydrogels
based
their
response
mechanisms
provide
an
in-depth
discussion
key
properties
mechanisms,
including
swelling
kinetics,
mechanical
properties,
biocompatibility/biodegradability.
We
then
explore
hydrogel
design,
synthesis,
structural
engineering,
followed
by
overview
applications
that
relatively
well
established
from
a
scientific
perspective,
biomedical
uses
(biosensing,
drug
delivery,
wound
healing,
tissue
engineering),
environmental
(heavy
metal
phosphate
removal
environment
polluted
water),
soft
robotics
actuation.
Additionally,
highlight
unconventional
such
as
local
micro-thermometers
cell
mechanotransduction.
concludes
with
current
challenges
future
prospects
field,
aiming
inspire
further
innovations
advancements
bring
them
closer
societal
needs.
Stimuli-responsive
hydrogels
hold
immense
promise
for
biomedical
applications,
but
conventional
gelation
processes
often
struggle
to
achieve
the
precision
and
complexity
required
advanced
functionalities
such
as
soft
robotics,
targeted
drug
delivery,
tissue
engineering.
This
study
introduces
a
class
of
3D-printable
magnetic
with
tunable
stiffness,
adhesion,
responsiveness,
prepared
through
simple
efficient
“one-pot”
method.
approach
enables
precise
control
over
hydrogel’s
mechanical
properties,
an
elastic
modulus
ranging
from
43
kPa
277
kPa,
tensile
strength
93
421
toughness
243
kJ/m3
1400
kJ/m3,
achieved
by
modulating
concentrations
acrylamide
(AM)
Fe3O4
nanoparticles.
These
exhibit
rapid
heating
under
alternating
field,
reaching
44.4
°C
within
600
s
at
15
wt%,
demonstrating
potential
use
in
mild
hyperthermia.
Furthermore,
integration
nanoparticles
nanoclay
into
AM
precursor
optimizes
rheological
properties
ensures
high
printability,
enabling
fabrication
complex,
high-fidelity
structures
extrusion-based
3D
printing.
Compared
existing
hydrogels,
our
platform
uniquely
combines
adjustable
strong
multifunctionality,
offering
enhanced
capabilities
actuation
hyperthermia
applications.
advancement
marks
significant
step
toward
scalable
production
next-generation
intelligent
medicine
bioengineering.
Biomimetics,
Год журнала:
2025,
Номер
10(4), С. 206 - 206
Опубликована: Март 26, 2025
The
application
background
of
mussel-inspired
materials
is
based
on
the
unique
underwater
adhesive
ability
marine
mussels,
which
has
inspired
researchers
to
develop
bionic
with
strong
adhesion,
self-healing
ability,
biocompatibility,
and
environmental
friendliness.
Specifically,
3,
4-dihydroxyphenylalanine
(DOPA)
in
mussel
byssus
able
form
non-covalent
forces
a
variety
surfaces,
are
critical
for
mussel's
adhesion
enable
material
dissipate
energy
repair
itself
under
external
forces.
Mussel-inspired
hydrogels
ideal
medical
due
their
physical
chemical
properties,
such
as
excellent
tissue
hemostasis
bacteriostasis,
biosafety,
plasticity.
This
paper
reviewed
chitosan,
cellulose,
hyaluronic
acid,
gelatin,
alginate,
other
biomedical
discussed
advanced
functions
wound
dressings,
including
antibacterial,
anti-inflammatory,
antioxidant
hemostasis,
transport,
self-healing,
stimulating
response,
so
on.
At
same
time,
technical
challenges
limitations
biomimetic
hydrogel
applications
were
further
discussed,
its
potential
solutions
future
research
developments
field
biomedicine
highlighted.
ACS Applied Materials & Interfaces,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 27, 2025
The
aging
population
necessitates
a
critical
need
for
medical
devices,
where
polymers-based
surface
lubrication
coating
is
essential
optimal
functionality.
In
fact,
and
mechanical
requirements
vary
depending
on
the
service
environment
of
different
devices.
Until
now,
key
mean
still
blank
general
preparation
hydrophilic
coatings
with
on-demand
mechanics
lubricity.
This
study
introduces
novel
tunable
properties
lubricity,
derived
from
eco-friendly
polymerizable
deep
eutectic
solvents
(PDESs)
containing
betaine,
hydroxyethyl
acrylate,
glycerol,
tannic
acid.
Unlike
traditional
high
molecular
weight
polymers,
this
approach
leverages
small-molecule,
high-biobased
PDESs,
thereby
simplifying
synthesis
process.
resulting
demonstrates
exceptional
adhesion
to
range
device
materials─including
glass,
stainless
steel,
polyvinyl
chloride,
polyurethane─thanks
content
hydroxyl
groups
pyrogallol
motifs
It
also
enables
precise
tuning
strength,
modulus,
adhesion,
hydrophilicity,
by
varying
amounts
glycerol
Furthermore,
undergoes
hydration-induced
transition
high-strength,
high-friction
low-strength,
low-friction
states,
maintaining
repeatable
performance.
Additionally,
synergistic
effects
betaine
acid
in
PDES
contribute
its
notable
antimicrobial
properties.
summary,
these
PDESs
demonstrate
significant
potential
enhancing
biomedical
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 28, 2025
Abstract
Inducibly
degradable
polymers
present
new
opportunities
to
integrate
tough
hydrogels
into
a
wide
range
of
biomaterials.
Rapid
and
inducible
degradation
enables
fast
transition
in
material
properties
without
sacrificing
integrity
prior
removal.
In
pursuit
bioorthogonal
chemical
modalities
that
will
enable
polymer
biologically
relevant
environments,
enamine
N
‐oxide
crosslinkers
are
developed
for
double
network
acrylamide‐based
polymer/alginate
hydrogels.
Bioorthogonal
dissociation
initiated
by
the
application
aqueous
diboron
solution
through
several
delivery
mechanisms
effectively
lead
degradation.
Their
B
2
(OH)
4
results
fracture
energy
half‐life
<10
min.
The
biocompatibility
reagent
is
assessed,
removability
strongly
adhered
on
mice
skin
evaluated.
Thermoresponsive
PNiPAAm/Alg
fabricated
as
chemically
intraoral
wound
dressing
demonstrated.
It
demonstrated
vivo
maximum
tolerated
dose
studies
administered
oral
gavage
well
tolerated.
Successful
integration
‐oxides
within
motifs
demonstrates
applicability
realm
chemistry
highlights
importance
induced
reactions
materials
science.
