Опубликована: Май 27, 2025
Язык: Английский
Опубликована: Май 27, 2025
Язык: Английский
Journal of Colloid and Interface Science, Год журнала: 2025, Номер 689, С. 137258 - 137258
Опубликована: Март 7, 2025
Язык: Английский
Процитировано
0ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown
Опубликована: Май 12, 2025
Three-dimensional (3D) printing technology has revolutionized the design and fabrication of bone scaffolds, offering precise customizable solutions for tissue engineering. In this study, we developed polycaprolactone (PCL) scaffolds that incorporated gold plasmonic blackbodies (AuPBs) to harness photothermal properties temperature-controlled regeneration. The AuPB-PCL demonstrated enhanced mechanical strength, a tunable thermal response under near-infrared (NIR) laser irradiation, improved osteogenic potential. Photothermal stimulation effectively modulated cellular responses, promoting osteoblast proliferation, alkaline phosphatase (ALP) activity, mineralization. Notably, mild hyperthermia (39-41 °C) induced by irradiation optimized osteogenesis, while excessive temperatures (≥42.5 impaired function due mitochondrial stress oxidative damage. These findings highlight potential controlled regeneration, promising strategy precise, completely noninvasive repair.
Язык: Английский
Процитировано
0Опубликована: Май 27, 2025
Язык: Английский
Процитировано
0