Published: May 27, 2025
Language: Английский
Published: May 27, 2025
Language: Английский
Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 689, P. 137258 - 137258
Published: March 7, 2025
Language: Английский
Citations
0ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown
Published: May 12, 2025
Three-dimensional (3D) printing technology has revolutionized the design and fabrication of bone scaffolds, offering precise customizable solutions for tissue engineering. In this study, we developed polycaprolactone (PCL) scaffolds that incorporated gold plasmonic blackbodies (AuPBs) to harness photothermal properties temperature-controlled regeneration. The AuPB-PCL demonstrated enhanced mechanical strength, a tunable thermal response under near-infrared (NIR) laser irradiation, improved osteogenic potential. Photothermal stimulation effectively modulated cellular responses, promoting osteoblast proliferation, alkaline phosphatase (ALP) activity, mineralization. Notably, mild hyperthermia (39-41 °C) induced by irradiation optimized osteogenesis, while excessive temperatures (≥42.5 impaired function due mitochondrial stress oxidative damage. These findings highlight potential controlled regeneration, promising strategy precise, completely noninvasive repair.
Language: Английский
Citations
0Published: May 27, 2025
Language: Английский
Citations
0