Organic Chemistry Frontiers,
Год журнала:
2020,
Номер
7(14), С. 1802 - 1808
Опубликована: Янв. 1, 2020
A
highly
efficient
iridium(iii)-catalyzed
arylation
coupling
of
sulfoxonium
ylides
with
arylboronic
acids
to
generate
α-aryl
ketones
has
been
established
for
the
first
time.
Organic Letters,
Год журнала:
2021,
Номер
23(3), С. 995 - 999
Опубликована: Янв. 27, 2021
In
this
work,
ruthenium(II)-catalyzed
C–C/C–N
annulation
of
2-arylquinazolinones
with
vinylene
carbonate
is
reported
to
synthesize
fused
quinazolinones.
This
catalytic
system
tolerates
a
wide
range
substrates
excellent
functional-group
compatibility.
transformation,
the
acts
as
an
ethynol
surrogate
without
any
external
oxidant
involved.
Furthermore,
preliminary
mechanistic
studies
were
conducted,
and
plausible
cycle
was
also
proposed.
Organic Chemistry Frontiers,
Год журнала:
2022,
Номер
9(16), С. 4388 - 4393
Опубликована: Янв. 1, 2022
The
synthesis
of
3-trifluoromethylisoquinolinones
by
a
ruthenium(
ii
)-catalyzed
C–H
activation/annulation
reaction
benzoic
acids
and
CF
3
-imidoyl
sulfoxonium
ylides
has
been
achieved.
Asian Journal of Organic Chemistry,
Год журнала:
2022,
Номер
11(4)
Опубликована: Март 23, 2022
Abstract
In
recent
years,
the
transition‐metal‐catalyzed
functionalization
reactions
of
sulfoxonium
ylides
have
been
explored
extensively
because
their
usefulness
as
carbene‐transfer
agents,
since
they
can
produce
metal
carbenes
through
catalysis.
Moreover,
are
safer
and
advantages
simple
handling
good
stability
over
other
counterparts
like
diazo‐compounds.
This
review
article
attempts
to
highlight
advances
in
metal‐catalyzed
C−H
ylides.
Organic Letters,
Год журнала:
2020,
Номер
22(12), С. 4806 - 4811
Опубликована: Июнь 1, 2020
Site-selective
direct
functionalization
of
an
indole
benzenoid
core
has
been
a
great
challenge
due
to
its
inherently
poor
reactivity.
We
herein
demonstrate
iridium-catalyzed
C4-selective
acylmethylation
indoles
using
α-carbonyl
sulfoxonium
ylides
as
carbene
precursors.
This
method
exhibits
high
efficiency
and
broad
functional
group
compatibility.
The
directing
was
easily
removed
or
converted
other
functionalities
after
the
catalysis.
potential
synthetic
utility
coupling
products
highlighted
by
constructing
medium-sized
polycyclic
indoles.
Organic Letters,
Год журнала:
2020,
Номер
22(4), С. 1375 - 1379
Опубликована: Фев. 3, 2020
The
synthesis
of
indanone
derivatives
by
the
Rh(III)-catalyzed
reaction
α-carbonyl
sulfoxonium
ylides
with
activated
alkenes
is
reported.
shows
a
high
tolerance
for
functional
groups
and
furnishes
variety
substituted
via
formal
[4
+
1]
cycloaddition.
Highly
stable
were
used
as
substrates
in
this
C-H
functionalization,
their
bifunctional
character
could
be
effectively
exploited
using
Rh(III)
catalysis
sequential
double
C-C
bond
formation.
Based
on
mechanistic
studies
including
deuterium-labeling
experiments,
proposed
to
proceed
follows:
oxidative
alkenylation
β-hydride
elimination,
readdition
H-Rh
species,
1,2-carbon
shift
elimination
DMSO,
protonation.
Organic & Biomolecular Chemistry,
Год журнала:
2022,
Номер
20(5), С. 1112 - 1116
Опубликована: Янв. 1, 2022
The
direct
synthesis
of
isocoumarin
skeletons
has
been
realized
through
the
Rh(
iii
)-catalyzed
[3
+
3]
annulation
sulfoxonium
ylides
and
iodonium
under
mild
conditions.
Chemical Society Reviews,
Год журнала:
2024,
Номер
53(11), С. 5904 - 5955
Опубликована: Янв. 1, 2024
Thermally
activated
delayed
fluorescence
(TADF)
emitters
have
become
increasingly
prominent
due
to
their
promising
applications
across
various
fields,
prompting
a
continuous
demand
for
developing
reliable
synthetic
methods
access
them.
This
review
aims
highlight
the
progress
made
in
last
decade
synthesizing
organic
TADF
compounds
through
C-H
bond
activation
and
functionalization.
The
begins
with
brief
introduction
basic
features
design
principles
of
emitters.
It
then
provides
an
overview
advantages
concise
development
transformations
constructing
Subsequently,
it
summarizes
both
transition-metal-catalyzed
non-transition-metal-promoted
used
synthesis
Finally,
gives
outlook
on
further
challenges
potential
directions
this
field.
Advanced Synthesis & Catalysis,
Год журнала:
2021,
Номер
363(5), С. 1436 - 1442
Опубликована: Янв. 21, 2021
Abstract
A
highly
efficient
cascade
Rh(III)‐catalyzed
C−H
activation/intramolecular
chemodivergent
cyclization
reaction
of
N‐carbamoylindoles
and
sulfoxonium
ylides
has
been
successfully
achieved
for
the
first
time.
This
synergistic
process
provides
rapid
access
to
functionalized
dihydropyrimidoindolone
tricyclic
[1,3]oxazino[3,4‐
a
]indol‐1‐ones
skeletons
under
redox
neutral
conditions
with
broad
substrate
scope
remarkable
functional‐group
compatibility.
Further
late‐stage
modification
structurally
complex
drug
molecules
mechanistic
studies
were
also
accomplished.
magnified
image
Organic Letters,
Год журнала:
2022,
Номер
24(18), С. 3395 - 3400
Опубликована: Май 5, 2022
The
transition-metal-catalyzed
C-H
functionalization
of
sulfoxonium
ylides
with
alkynes
formally
participates
in
[4
+
2]
annulations
to
deliver
the
naphthol
scaffolds.
In
contrast,
herein
we
disclose
first
Rh(III)-catalyzed
activation,
followed
by
redox-neutral
[3
annulation
1,3-diynes,
which
delivers
alkynated
indenone
derivatives.
This
protocol
features
a
good
functional
group
tolerance,
broad
substrate
scope,
moderate
excellent
yields,
and
mild
reaction
conditions.
mechanism
was
supported
through
ESI-HRMS
characterizing
key
intermediates
catalytic
cycle.
