Expeditious synthesis of CF3-phenanthridones through a base mediated cross-conjugated vinylogous benzannulation (VBA) DOI

Madhu Desagoni,

Chavakula Nagababu,

Nagender Punna

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Herein, we report a mild, efficient, and rapid approach for the preparation of CF

Язык: Английский

Access to CF3-benzofulvenes via palladium-catalyzed cascade arylation/Trost–Oppolzer cyclization/double-bond isomerization DOI

Rami Sateesh,

Jaggaraju Prudhviraj,

Chiliveru Priyanka

и другие.

Chemical Communications, Год журнала: 2024, Номер 60(26), С. 3551 - 3554

Опубликована: Янв. 1, 2024

Highly stereoselective synthesis of CF 3 -benzofulvenes has been achieved through a Pd-catalyzed cascade reaction involving three consecutive transformations such as arylation, Trost–Oppolzer type Alder-ene reaction, and double bond isomerization.

Язык: Английский

Процитировано

3
CsCF3B(OMe)3: A Versatile Nucleophilic Source of the Trifluoromethyl Anion DOI

Aurélien Dupeux,

Andrew G. Durant,

Karolina Rabeda

и другие.

Synthesis, Год журнала: 2025, Номер unknown

Опубликована: Фев. 5, 2025

Abstract We have identified cesium trimethoxy(trifluoromethyl)borate [CsCF3B(OMe)3] as a nucleophilic source for the trifluoromethylation of carbonyl compounds. A differentiating characteristic CsCF3B(OMe)3 is its heightened reactivity in ethereal solvents compared to potassium analogue, which typically employed dimethylformamide. Also, contrast extensively studied Ruppert–Prakash reagent (TMSCF3), does not require addition an exogenous activator. Described herein, we detail synthesis and demonstrate efficacy across various scaffolds, including methyl ketones, isatin derivatives, 1,2-acyclic dicarbonyls.

Язык: Английский

Процитировано

0
Cross-conjugated vinylogous annulation of π-CF3-allyl Pd-complexes with 4-methyl-3-trifluoroacetyl-quinolones DOI

Chiliveru Priyanka,

Madhu Desagoni,

Palivela Siva Gangadhar

и другие.

Chemical Communications, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

A hitherto unknown cross-conjugated vinylogous anionic annulation of π-CF 3 -allyl Pd-complexes with 4-methyl-3-trifluoroacetyl quinolones has been disclosed to access the diversely functionalized phenanthridones.

Язык: Английский

Процитировано

1
Pd-catalyzed double Heck and Heck–Suzuki cascade reaction of N-(o-bromo aryl) CF3-acrylamides DOI
Ruchi Sharma, Naveen Sihag, Hemaang Bhartiya

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(6), С. 1736 - 1741

Опубликована: Янв. 1, 2024

A double Heck and Heck–Suzuki cascade approach using Pd catalyst yields trifluoromethyl-tethered 3,3-disubstituted oxindoles from N -( o -bromoaryl) trifluoromethyl acrylamide with alkenes/phenylboronic acids.

Язык: Английский

Процитировано

0
Expeditious synthesis of CF3-phenanthridones through a base mediated cross-conjugated vinylogous benzannulation (VBA) DOI

Madhu Desagoni,

Chavakula Nagababu,

Nagender Punna

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Herein, we report a mild, efficient, and rapid approach for the preparation of CF

Язык: Английский

Процитировано

0