Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 123 - 173
Опубликована: Янв. 1, 2024
Язык: Английский
Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 123 - 173
Опубликована: Янв. 1, 2024
Язык: Английский
Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(9), С. 2665 - 2692
Опубликована: Янв. 1, 2024
The synthesis of small molecules and complex scaffolds is one the most important topics in organic synthesis.
Язык: Английский
Процитировано
20ChemistrySelect, Год журнала: 2025, Номер 10(1)
Опубликована: Янв. 1, 2025
Abstract 1,4‐Naphthoquinones (1,4‐NQs) are an important class of molecules with diverse pharmaceutical applications. Lawsone, a naturally occurring molecule range bioactivities, falls in the 1,4‐NQs. It possesses 1,3‐dicarbonyl functionality, which has been utilized synthesis bis‐lawsones reaction aldehydes. In this review we have discussed notable developments bis‐lawsone from 2009 to 2023. Also, highlights limitations and future perspectives area.
Язык: Английский
Процитировано
2Tetrahedron, Год журнала: 2024, Номер 166, С. 134210 - 134210
Опубликована: Авг. 27, 2024
Язык: Английский
Процитировано
4The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Март 11, 2025
A new approach to multifunctionalized pyrroles has been explored by the tandem cyclization of α-oxoketene-N,S-acetals with β-ketodinitriles using Cu(MeCN)4BF4 and Ag2CO3 in toluene under reflux conditions. The reaction involves C–C/C–N bond creation, is assumed proceed via enamine formation, intramolecular cyclization, rearrangement. potential methodology also demonstrated for a gram-scale as well some useful organic transformations. offers practical pathway achieve polysubstituted broad substrate scope good functional group tolerance.
Язык: Английский
Процитировано
0International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142283 - 142283
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(10), С. 6974 - 6986
Опубликована: Май 4, 2024
A LiBr-promoted formal C(sp3)–H bond insertion reaction between β-carbonyl esters and sulfoxonium ylides is established. This practical has a wide range of substrate scope for both to give variety 1,4-dicarbonyl compounds with 43–94% yields. The features transition-metal-free conditions exclusive C-alkylation chemselectivity. use bench-stable overcomes previous methods that require transition metal as catalysts unstable diazo or toxic haloketones alkylation reagents.
Язык: Английский
Процитировано
2Advanced Synthesis & Catalysis, Год журнала: 2024, Номер 366(21), С. 4399 - 4403
Опубликована: Июль 16, 2024
Abstract A multicomponent cascade cyclization reaction using aryl methyl ketones, amines, and enaminamide reagents to construct 3‐hydroxy‐1 H ‐pyrrolo[3,4‐ b ]quinolin‐1‐one skeleton with good substrate compatibility (50 examples) has been reported. The one‐pot, metal‐free process formed two C−C bonds, C−N a tetrasubstituted carbon stereocenter containing hydroxyl group. enabled modified transformation of drug molecules derivatization products.
Язык: Английский
Процитировано
0The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(21), С. 16049 - 16054
Опубликована: Окт. 21, 2024
The synthesis of polyfunctionalized pyrroles via the cascade reactions 1,3-dicarbonyl compounds and two molecules ethyl secondary amines has been realized simple iodine catalysis in presence Dess-Martin periodinane (DMP). formation target pyrrole products involves one new C-C C-N bonds major functionalization six C(sp
Язык: Английский
Процитировано
0ChemistrySelect, Год журнала: 2024, Номер 9(40)
Опубликована: Окт. 1, 2024
Abstract An effective DABCO‐promoted (4+1) annulation reaction for the synthesis of ethyl (2‐amino‐1H‐pyrrol‐1‐yl)acetate derivatives from 2‐aroyl‐3‐arylcyclopropane‐1,1‐dicarbonitriles and glycinate was developed. This strategy is characterized by readily accessible starting materials, mild conditions, simplicity operation.
Язык: Английский
Процитировано
0Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 123 - 173
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0