Machine learning-assisted nanosensor arrays: An efficiently high-throughput food detection analysis

Trends in Food Science & Technology, Год журнала: 2024, Номер 149, С. 104564 - 104564

Опубликована: Май 27, 2024

Язык: Английский

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Polyphenol-modified 3D Nanoassemblies: A novel antibacterial immunoglobulins loading platform for rapid detection of Salmonella typhimurium

Food Chemistry, Год журнала: 2025, Номер 472, С. 142895 - 142895

Опубликована: Янв. 13, 2025

Язык: Английский

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Nanozymes meet hydrogels: Fabrication, progressive applications, and perspectives

Advances in Colloid and Interface Science, Год журнала: 2025, Номер 338, С. 103404 - 103404

Опубликована: Янв. 23, 2025

Язык: Английский

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Asymmetric Nanobowl Confinement-Engineered “Plasmonic Storms” for Machine Learning-Assisted Ultrasensitive Immunochromatographic Assay of Pathogens

Analytical Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Сен. 9, 2024

Efficient field enhancement effects through plasmonic chemistry for ultrasensitive biosensing still face a great challenge. Herein, nanoconfinement engineering accumulation and synergistic are used to develop "plasmonic storms" strategy with high effect, gold nanoparticles (AuNPs) as active sites proof of concept because their distinctive localized surface plasmon resonance neighborly coupled electromagnetic field. Briefly, large number AuNPs selectively accurately stacked in the confined nanocavity bowl-like nanostructure an situ-synthesized strategy, which provides space strong coupling fields between these adjacent AuNPs, forming enhanced that is 3 orders magnitude higher than free AuNPs. The proposed nanoconfinement-engineered demonstrated by surface-enhanced Raman scattering (SERS) photothermal experiments theoretically visualized finite element simulation. Finally, colorimetric/SERS/photothermal immunochromatographic assay detect

Язык: Английский

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Recent advances of aggregation-induced emission luminogens for point-of-care biosensing systems

Chemical Communications, Год журнала: 2024, Номер 60(65), С. 8484 - 8496

Опубликована: Янв. 1, 2024

Aggregation-induced emission (AIE)-based POC detection is important for diagnosis of diseases and assessment the effectiveness treatment programs. This review summarized advancement design application AIE-based biosensors.

Язык: Английский

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Bidirectional “Win–Win”: Asymmetrical Nanobowl-Coupled Aggregation-Induced Emissive Nanosilicon-Enhanced Immunochromatographic Strips for the Ultrasensitive Detection of Salmonella typhimurium

Analytical Chemistry, Год журнала: 2024, Номер 96(45), С. 18204 - 18213

Опубликована: Ноя. 1, 2024

The lack of nanoprobes with an efficient signal response and overlook cooperation between can be responsible for the unsatisfactory analytical performance immunochromatographic strips (ITSs). Herein, asymmetrical nanobowl-confined innumerable gold nanoparticles (AuNPs) (AuNPs@AFRNBs) to enhance light absorption are developed quenching fluorescence aggregation-induced emissive (AIE) nanosilicons, which is used construction a bidirectional complementary-enhanced ITS (BC-ITS) ultrasensitively detect

Язык: Английский

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The Outputs of Molecular Sensors Detectable by Human Senses

Chemical Communications, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Molecular sensors respond to the presence of biological analytes by producing signals that are either directly perceivable human sensory systems or converted into electric signals, which require electronic devices for communicating humans. Here, we review outputs molecular detectable senses. According literature, with visual dominate. Undeservedly unnoticed, release gases might be particularly useful since gas output can detected several senses in a quantifiable format. Relatively new tactile accessed visually impaired people. their bypassing may contribute development point-of-care testing technologies, as well providing direct communication nanorobots

Язык: Английский

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Aggregation Induced Emissive Liquid Crystals‐Polymer Composite Membrane for Dual‐Channel Analysis of Parathyroid Hormone

Aggregate, Год журнала: 2025, Номер unknown

Опубликована: Фев. 2, 2025

ABSTRACT Parathyroid hormone (PTH) is an important factor in maintaining blood calcium levels the human body. Therefore, monitoring PTH essential for assessing various diseases progression and managing overall health. In this study, a fluorescence optical sensor based on aggregation‐induced emissive liquid crystal photopolymer (AIE‐LC‐Poly) film was established qualitative quantitative detection of PTH. The specific interaction between anti‐PTH substrate surface utilized, variations orientation aggregation state fluorescent LCs were evaluated by both optic means. limit using image above 10 µg/mL, while achieved much lower 1 ng/mL. Additionally, further amplified signals strengthening AIE effect initiate state, enhancing disturbance ordered upon addition. Ultimately, limits reduced to 0.01 µg/mL 50 pg/mL detection. sensitive AIE‐LC‐Poly biosensing technology presented here sets stage develop LC‐based biomedical applications without labeling.

Язык: Английский

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Mapping human fingerprint beyond level-3 based on an amphiphilic aggregation-induced emission luminogen and the construction of intelligent platform for personal identification

Analytica Chimica Acta, Год журнала: 2025, Номер 1352, С. 343927 - 343927

Опубликована: Март 11, 2025

Язык: Английский

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BE-CATCH: Bioamplifier-Equipped CRISPR-Cas12a Transduction System Coupled with Commercial Pregnancy Test Strips to Harness Signal-on Point-of-Care Detection

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 15, 2025

Repurposing existing commercial diagnostic equipment to enable portable analysis of diverse targets is driving the development affordable point-of-care testing (POCT). Interestingly, we found that goat antimouse IgG could replace human chorionic gonadotropin (hCG) make T line pregnancy test strips (PTS) appear red color and accordingly synthesized a novel signal output probe, which eliminated intricate hCG covalent coupling steps, meet multiple needs expanded POCT. Given this, introduced separation-free universal POCT strategy termed bioamplifier-equipped CRISPR-Cas12a transduction system coupled with PTS harness signal-on detection (BE-CATCH). Specifically, target inputs were converted amplified by multiplied strand displacement amplification-based bioamplifier, thereby activating Cas12a's trans-cleavage activity. Then, activated Cas12a would cleave connector indiscriminately, ultimately kept probe in free state; thus, be translated into colorimetric on PTS. This not only provided boosted sensitivity specificity but also enhanced user-friendliness maintaining mode. We demonstrated versatility BE-CATCH through selectively detecting miR-155 flap endonuclease 1. its broad adaptability, provide an appealing option broaden application biomedical diagnostics.

Язык: Английский

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