Organic Nitrating Reagents
Synthesis,
Год журнала:
2022,
Номер
54(15), С. 3432 - 3472
Опубликована: Апрель 13, 2022
Abstract
Nitro
compounds
are
vital
raw
chemicals
that
widely
used
in
academic
laboratories
and
industries
for
the
preparation
of
various
drugs,
agrochemicals,
materials.
Thus,
nitrating
reactions
great
importance
chemists
even
taught
schools
as
one
fundamental
transformations
organic
synthesis.
Since
discovery
first
19th
century,
progress
this
field
has
been
constant.
Yet,
many
years
classical
electrophilic
nitration
approach
using
a
mixture
strong
mineral
acids
dominated
field.
However,
recent
decades,
attention
researchers
focused
on
new
reactivity
reagents
can
provide
access
to
nitro
practical
straightforward
way
under
mild
reaction
conditions.
Organic
have
played
special
role
since
they
enhanced
reactivity.
They
also
allow
be
carried
out
an
ecofriendly
sustainable
manner.
This
review
examines
development
application
reagents.
1
Introduction
2
Nitrating
Reagents
2.1
Alkyl
Nitrites
2.2
Nitroalkanes
2.3
Nitrates
2.4
N-Nitroamides
2.5
N-Nitropyrazole
2.6
N-Nitropyridinium
Salts
3
Generated
In
Situ
3.1
Acyl
3.2
Trimethylsilyl
Nitrate
3.3
Onium
4
Nitronium
5
5.1
Ammonium
5.2
Heteroarylium
5.3
Other
5.4
6
Conclusion
Outlook
Язык: Английский
Visible-Light-Initiated Difunctionalization of Quinoxalin-2(1H)-ones with Acyloxy Nitroso Compounds
Organic Letters,
Год журнала:
2022,
Номер
24(39), С. 7118 - 7122
Опубликована: Сен. 25, 2022
Herein,
a
photoinitiated
radical
relay
reaction
of
quinoxalin-2(1H)-ones,
with
acyloxy
nitroso
compounds
as
source
radicals,
is
described.
Although
the
C-H
functionalization
quinoxalin-2(1H)-ones
has
been
investigated,
its
difunctionalization,
simultaneous
construction
C-C
and
N-N
bonds
directly
via
reaction,
rarely
reported.
Moreover,
obtained
products
underwent
sequential
reactions
to
access
C7-NO2
under
mild
conditions.
Язык: Английский
Electrochemical Nitration with Nitrite
Stephan P. Blum,
Christean Nickel,
Lukas Schäffer
и другие.
ChemSusChem,
Год журнала:
2021,
Номер
14(22), С. 4936 - 4940
Опубликована: Сен. 28, 2021
Aromatic
nitration
has
tremendous
importance
in
organic
chemistry
as
nitroaromatic
compounds
serve
versatile
building
blocks.
This
study
represents
the
electrochemical
aromatic
with
NBu
Язык: Английский
Ag/Se‐Catalyzed Selective Epoxidation of β‐Ionone with Molecular Oxygen
ChemistrySelect,
Год журнала:
2022,
Номер
7(37)
Опубликована: Окт. 5, 2022
Abstract
Ag/Se
could
be
easily
fabricated
by
calcining
selenium
and
silver
powders.
It
was
found
to
an
efficient
catalyst
for
the
selective
epoxidation
of
endocyclic
C=C
bond
β
‐ionone
produce
epoxide,
important
organic
intermediate
in
pharmaceutical
industry.
is
notable
that
reaction
can
employ
molecular
oxygen
as
cheap,
clean
relatively
safe
oxidant,
no
additives
such
NHPI
are
required.
The
green
process
makes
method
practical
large‐scale
application.
Язык: Английский
Electrophilic Aromatic Substitution
Organic Reaction Mechanisms/Organic reaction mechanisms,
Год журнала:
2023,
Номер
unknown, С. 213 - 255
Опубликована: Янв. 20, 2023
The
significance
of
aromatic
and
heterocyclic
compounds
in
both
industry
academia
ensures
that
investigations
into
new
methods
electrophilic
substitution
(EAS)
the
underlying
mechanisms
such
transformations
continue
to
receive
considerable
attention.
Halogenation
continues
be
an
important
area
investigation
EAS,
where
more
than
one
halogens
can
introduced
have
been
described.
Studies
on
bromination
their
much
Hydrogen
peroxide
has
used
combination
with
potassium
bromide
brominate
porphyrins
a
biphasic
system.
New
mechanistic
insights
iodination
presented.
use
anthraquinone
presence
TFA
as
photocatalyst
allows
visible-light-promoted
electron-rich
arenas.
Recent
research
classic
ever
nitration
reaction
includes
computational
studies
greener,
environmentally
friendly
methods.
Язык: Английский
Recent Advances in Functionalization of Aromatic C(sp2)—H Bonds Based on N-Nitroso Direction
Chinese Journal of Organic Chemistry,
Год журнала:
2023,
Номер
43(12), С. 4157 - 4157
Опубликована: Янв. 1, 2023
Язык: Английский
Photocatalytic aerobic oxidative deoximation reaction with degradable rhodamine B
Reaction Chemistry & Engineering,
Год журнала:
2022,
Номер
8(4), С. 849 - 854
Опубликована: Дек. 22, 2022
Photocatalytic
aerobic
oxidative
deoximation
with
rhodamine
B
affords
a
new
method
for
organic
synthesis.
Compared
reported
works,
the
photosensitizer
was
cheap
and
degradable,
while
substrate
scope
of
reaction
wide.
Язык: Английский
Nucleophilic Aromatic Substitution
Organic Reaction Mechanisms/Organic reaction mechanisms,
Год журнала:
2023,
Номер
unknown, С. 179 - 211
Опубликована: Янв. 20, 2023
A
chlorogermabenzene
has
been
generated
by
reaction
of
an
aluminacyclohexadiene
with
germanium
chloride.
The
cyanodemethoxylation
arenes
accomplished
using
a
highly
oxidizing
acridinium
photoredox
catalyst
acetone
cyanohydrin
as
the
source
cyanide.
Arenediazonium
triflates
have
synthesized
diazotization
anilines
t
-butylnitrite
in
presence
trifluoromethanesulfonic
acid.
detection
2,4,6-trinitrotoluene
remains
active
area
research,
most
methods
relying
on
its
interaction
amino
groups.
Likely
modes
include
Meisenheimer
complex
formation
and
anion
transfer
methyl
proton.
It
shown
that
1,2-azaborine,
boron–nitrogen
equivalent
ortho
-benzyne,
super-electrophilic
boron
centre
will
form
adducts
xenon
carbon
monoxides
under
matrix
isolation
conditions.
Nucleophilic
attack
chlorine
ions
benzyne
gives
anions
may
be
trapped
dioxide
to
ortho-chlorobenzoate
ion.
Язык: Английский
Oxidation and Reduction
Organic Reaction Mechanisms/Organic reaction mechanisms,
Год журнала:
2023,
Номер
unknown, С. 65 - 140
Опубликована: Янв. 20, 2023
A
total
of
24
reviews
including
6
mini
and
4
accounts
are
published
in
2019.
The
first
the
describes
processing
polysaccharides,
particularly
recalcitrant
insoluble
such
as
cellulose
lignocellulosic
biomass,
by
lytic
polysaccharide
monooxygenases
(LPMOs),
a
monocopper
enzyme.
LPMO
reactions
driven
both
molecular
oxygen
hydrogen
peroxide.
application
an
azo-phenolate
ligand-coordinated
nickel
catalyst
N-alkylation
variety
anilines
alcohols
is
reported.
redox-active
azo
ligand
stores
generated
during
alcohol
oxidation
redelivers
it
to
situ
imine
leading
amine.
simple
efficient
protocol
for
regioselective
indoles
2-oxindoles
using
sulfuric
acid
adsorbed
on
silica
gel
reagent
reaction
has
broad
substrate
scope
functional
group
tolerance.
Язык: Английский
Nitration of N -acetyl anilides using silver(I) nitrate/persulfate combination
Synthetic Communications,
Год журнала:
2022,
Номер
52(9-10), С. 1279 - 1289
Опубликована: Май 19, 2022
Nitration
of
N-acetyl
anilides
using
a
simple
combination
AgNO3
and
K2S2O8
as
stable
nitro
source
an
oxidant,
respectively,
was
explored.
The
reaction
practical
to
operate
proceeded
under
considerably
mild
conditions
(reflux
in
acetonitrile)
within
acceptable
time
(6
h).
para-substituted
gave
only
ortho-nitrated
products
moderate
good
yields
(30–63%
yields).
ortho-,
meta-,
or
non-substituted
mixture
nitrated
(30–72%
combined
yields)
with
preferentially
at
the
para-
over
ortho-position
(ortho:para;
1.0:1.1–1.0:2.8).
Язык: Английский