Research Square (Research Square),
Год журнала:
2023,
Номер
unknown
Опубликована: Фев. 23, 2023
Abstract
Photocatalytic
C
−
coupling
reaction
plays
an
important
role
in
the
synthesis
of
organics
that
are
widely
used
as
fine
chemicals,
medicine
and
pesticides.
However,
development
high-performance,
low-cost
photocatalysts
to
drive
under
mild
conditions
remains
a
severe
challenge.
Herein,
we
present
green
photocatalytic
method
for
selective
bibenzyl
over
ultrathin
TiO
2
(B)
nanosheet
photocatalyst
with
single-atom
Cu
anchored
rich
oxygen
vacancy
(V
O
),
which
were
generated
in-situ
system.
The
requires
no
tedious
pre-functionalization
steps,
allows
use
cheap
copper
compounds
starting
materials.
experimental
results
show
introduction
sites
on
can
improve
charge
transfer
separation
efficiency,
presence
surface
V
not
only
improves
light
absorption
capacity
but
also
favors
adsorption
activation
reactant
benzyl
bromide.
More
importantly,
synergy
endows
high
efficiency
bibenzyl.
This
work
provides
novel
insight
into
through
collaborative
strategy
species
photocatalysts.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(9), С. 6334 - 6344
Опубликована: Апрель 15, 2024
A
one-pot
strategy
for
deoxygenative
alkylation
of
alcohols
with
quinoxalin-2(1H)-ones
was
developed
by
using
xanthate
salts
as
alcohol-activating
groups
radical
generation
in
the
presence
tricyclohexylphosphine
under
visible-light-promoted
conditions.
The
remarkable
features
this
reaction
include
a
broad
substrate
scope,
excellent
functional
group
tolerance,
mild
conditions,
and
simple
operation.
Moreover,
synthetic
utility
validated
success
two-step
reactions,
scale-up
synthesis,
chemoselective
monodeoxygenation
diols.
Organic Letters,
Год журнала:
2024,
Номер
26(2), С. 450 - 455
Опубликована: Янв. 8, 2024
δ-Hydroxy
chloronitroso
compounds
generated
in
situ
from
1,2-oxazine
N-oxides
undergo
a
1,5-hydride
transfer
related
to
the
Meerwein–Ponndorf–Verley–Oppenauer
reaction.
Based
on
process
discovered,
three-step
access
fused
pyrrolidine
scaffolds
containing
up
four
contiguous
stereogenic
centers
starting
simple
nitrostyrenes
and
cycloalkenes
or
cyclodienes
has
been
developed.
The
suggested
reaction
mechanism
was
confirmed
by
UV–vis
ATR
FT-IR
monitoring
DFT
calculations.
Herein,
we
report
a
visible
light-mediated
sequential
reaction
involving
in
situ
generation
of
benzotriazole
from
benzene-1,2-diamine
and
tert-butyl
nitrite
via
nitrogen
insertion
concomitant
cross-coupling
with
quinoxaline-2(1H)-ones
C-N
bond
formation
one
pot.
This
protocol
uses
metal-free
mild
conditions
demonstrated
36
examples
≤80%
yield
wide
functional
group
tolerance.
Organic & Biomolecular Chemistry,
Год журнала:
2023,
Номер
21(10), С. 2232 - 2235
Опубликована: Янв. 1, 2023
A
direct,
aerobic
and
visible
light
photocatalytic
approach
to
synthesize
4-thiocyanated
5-hydroxy-1H-pyrazoles
via
cross-coupling
of
pyrazolin-5-ones
with
ammonium
thiocyanate
is
described.
Under
redox-neutral
metal-free
conditions,
a
series
could
be
easily
efficiently
obtained
in
good
high
yields
by
using
low-toxicity
inexpensive
as
the
source.
